Question 1

Which of the following hormones binds to a receptor tyrosine kinase?

Accepted Answer

A) thyroxine 
B) epinephrine 
C) epidermal growth factor 
D) glucagon 
E) cortisol 
A) thyroxine 
B) epinephrine 
C) epidermal growth factor 
D) glucagon 
E) cortisol

Question 2

Amphetamine and mescaline are agonists of ____________, the neurotransmitter often considered a "pleasure agent."

Accepted Answer

A) serotonin 
B) $\gamma$-aminobutyric acid 
C) N-methyl-D-aspartate 
D) glutamate 
E) dopamine 
A) serotonin 
B) $\gamma$-aminobutyric acid 
C) N-methyl-D-aspartate 
D) glutamate 
E) dopamine

Question 3

A G protein is inactive when the _____ subunit is bound to __________.

Accepted Answer

A) $\alpha$; GMP 
B) $\alpha$; GDP 
C) $\beta$; GMP 
D) $\beta$; GDP 
E) $\beta$/$\gamma$; GMP 
A) $\alpha$; GMP 
B) $\alpha$; GDP 
C) $\beta$; GMP 
D) $\beta$; GDP 
E) $\beta$/$\gamma$; GMP

Question 4

Which of the following pathways correctly shows how glycogen synthase is activated in response to the activation of IRS-1 by insulin binding?

Accepted Answer

A) IRS-1 causes activation of protein kinase B which phosphorylates glycogen synthase kinase thus preventing phosphorylation of glycogen synthase 
B) IRS-1 activates a cascade that ultimately phosphorylates ERK which then binds to glycogen synthase 
C) IRS-1 activates phosphoinositide 3-kinase and the resulting PIP3 is an allosteric activator of glycogen synthase 
D) IRS-1 activates guanylate cyclase and the resulting cGMP binds to glycogen synthase kinase thus preventing phosphorylation of glycogen synthase 
E) none of the above 
A) IRS-1 causes activation of protein kinase B which phosphorylates glycogen synthase kinase thus preventing phosphorylation of glycogen synthase 
B) IRS-1 activates a cascade that ultimately phosphorylates ERK which then binds to glycogen synthase 
C) IRS-1 activates phosphoinositide 3-kinase and the resulting PIP3 is an allosteric activator of glycogen synthase 
D) IRS-1 activates guanylate cyclase and the resulting cGMP binds to glycogen synthase kinase thus preventing phosphorylation of glycogen synthase 
E) none of the above

Which of the following hormones binds to a receptor tyrosine kinase?

Amphetamine and mescaline are agonists of ____________, the neurotransmitter often considered a "pleasure agent."

A G protein is inactive when the _ subunit is bound to ______.

Which of the following pathways correctly shows how glycogen synthase is activated in response to the activation of IRS-1 by insulin binding?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Nucleic Acids

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

Exam 23: Mechanisms of Signal Transduction

Which of the following hormones binds to a receptor tyrosine kinase?

Amphetamine and mescaline are agonists of ____________, the neurotransmitter often considered a "pleasure agent."

A G protein is inactive when the _____ subunit is bound to __________.

Which of the following pathways correctly shows how glycogen synthase is activated in response to the activation of IRS-1 by insulin binding?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Nucleic Acids

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

A G protein is inactive when the _ subunit is bound to ______.