Question 1

During apoptosis, proteolysis is catalyzed by ______________ enzymes.

Accepted Answer

A) ubiquitin 
B) autophagic lysosomal protease 
C) phagocytic protease 
D) HSP protease 
E) caspase 
A) ubiquitin 
B) autophagic lysosomal protease 
C) phagocytic protease 
D) HSP protease 
E) caspase

Question 2

In a eukaryotic cell, what protein factor is responsible for delivering each aminoacyl-tRNA to the ribosome?

Accepted Answer

A) EF-Tu 
B) EF-Ts 
C) eEF1$\alpha$ 
D) eEF1$\beta$$\gamma$ 
E) eEF2 
A) EF-Tu 
B) EF-Ts 
C) eEF1$\alpha$ 
D) eEF1$\beta$$\gamma$ 
E) eEF2

Question 3

What is the energy requirement for the formation of the 70S initiation complex?

Accepted Answer

A) 1 GTP 
B) 1 ATP 
C) 1 GTP and 1 ATP 
D) 2 GTP (from hydrolysis of 1 GTP to GMP) 
E) 2 ATP (from hydrolysis of 1 ATP to AMP) 
A) 1 GTP 
B) 1 ATP 
C) 1 GTP and 1 ATP 
D) 2 GTP (from hydrolysis of 1 GTP to GMP) 
E) 2 ATP (from hydrolysis of 1 ATP to AMP)

Question 4

What role do the Hsp70 proteins play in delivering proteins to their site of action such as the mitochondria?

Accepted Answer

A) aids in proper folding to allow protein to properly traverse membranes 
B) prevents proteolysis of the unfolded protein 
C) keeps the protein in an unfolded state to allow transfer across membranes 
D) aids in formation of an intermediate folded protein that is present only during membrane transport 
E) none of the above 
A) aids in proper folding to allow protein to properly traverse membranes 
B) prevents proteolysis of the unfolded protein 
C) keeps the protein in an unfolded state to allow transfer across membranes 
D) aids in formation of an intermediate folded protein that is present only during membrane transport 
E) none of the above

Question 5

What site is occupied by the tRNAfMet during intitiation?

Accepted Answer

A) A site 
B) P site 
C) E site 
D) binds first to A site then moves to P site 
E) binds first to P site then moves to E site 
A) A site 
B) P site 
C) E site 
D) binds first to A site then moves to P site 
E) binds first to P site then moves to E site

Question 6

Which of the following is a difference between prokaryotic and eukaryotic translation?

Accepted Answer

A) the genetic code is different 
B) prokaryotic ribosomes are free in the cytosol; eukaryotic chromosomes are always membrane bound 
C) eukaryotic translation requires more protein factors 
D) the ribosomes in prokaryotes are larger 
E) none of the above 
A) the genetic code is different 
B) prokaryotic ribosomes are free in the cytosol; eukaryotic chromosomes are always membrane bound 
C) eukaryotic translation requires more protein factors 
D) the ribosomes in prokaryotes are larger 
E) none of the above

Question 7

Which of the bases present on the ribosome participates in the peptidyltransferase reaction?

Accepted Answer

A) A 
B) C 
C) G 
D) T 
E) U 
A) A 
B) C 
C) G 
D) T 
E) U

Question 8

Proteins destined for extracellular transport produce an N-terminal signal sequence. What binds to this sequence for endoplasmic reticulum association?

Accepted Answer

A) signal recognition particle 
B) ribosome receptor protein 
C) Sec61 docking protein 
D) SNARE protein 
E) none of the above 
A) signal recognition particle 
B) ribosome receptor protein 
C) Sec61 docking protein 
D) SNARE protein 
E) none of the above

During apoptosis, proteolysis is catalyzed by ______________ enzymes.

In a eukaryotic cell, what protein factor is responsible for delivering each aminoacyl-tRNA to the ribosome?

What is the energy requirement for the formation of the 70S initiation complex?

What role do the Hsp70 proteins play in delivering proteins to their site of action such as the mitochondria?

What site is occupied by the tRNA^fMet during intitiation?

Which of the following is a difference between prokaryotic and eukaryotic translation?

Which of the bases present on the ribosome participates in the peptidyltransferase reaction?

Proteins destined for extracellular transport produce an N-terminal signal sequence. What binds to this sequence for endoplasmic reticulum association?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Nucleic Acids

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Regulation of Gene Expression

Filters

Exam 28: Information Decoding: Translation and Post-Translational Protein Processing

During apoptosis, proteolysis is catalyzed by ______________ enzymes.

In a eukaryotic cell, what protein factor is responsible for delivering each aminoacyl-tRNA to the ribosome?

What is the energy requirement for the formation of the 70S initiation complex?

What role do the Hsp70 proteins play in delivering proteins to their site of action such as the mitochondria?

What site is occupied by the tRNAfMet during intitiation?

Which of the following is a difference between prokaryotic and eukaryotic translation?

Which of the bases present on the ribosome participates in the peptidyltransferase reaction?

Proteins destined for extracellular transport produce an N-terminal signal sequence. What binds to this sequence for endoplasmic reticulum association?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Nucleic Acids

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Regulation of Gene Expression

Filters

What site is occupied by the tRNA^fMet during intitiation?