Question 1

Match each of the following terms with its correct definition.
-genomics

Accepted Answer

A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome 
A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome

Question 2

During a sequencing reaction, the researcher adds all the required components to the reaction, but accidentally adds only one of the four dideoxynucleotides, the ddC. What kinds of products will be observed after this reaction is complete?

Accepted Answer

A) All fragments will end in A. 
B) All fragments will end in C. 
C) All fragments will end in G. 
D) All fragments will end in T. 
A) All fragments will end in A. 
B) All fragments will end in C. 
C) All fragments will end in G. 
D) All fragments will end in T.

Question 3

Which of the following is NOT added to a single-stranded DNA in order to perform a successful sequencing reaction?

Accepted Answer

A) a mixture of the four dideoxyribonucleotides, not labelled with a different fluorescent label 
B) a DNA primer 
C) a mixture of the four deoxyribonucleotides 
D) a DNA polymerase 
A) a mixture of the four dideoxyribonucleotides, not labelled with a different fluorescent label 
B) a DNA primer 
C) a mixture of the four deoxyribonucleotides 
D) a DNA polymerase

Question 4

Match the following techniques with the descriptions listed below.
-used to replace a normal gene with a defective one to see the effect

Accepted Answer

A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown 
A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown

Question 5

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below.
-genomics

Accepted Answer

A) DNA 
B) mRNA/cDNA 
C) protein 
A) DNA 
B) mRNA/cDNA 
C) protein

Question 6

Comparative genomics is done to learn how genes and genomes have evolved. What are three different concepts that we have learned from comparative genomics?

Accepted Answer

By comparing genomes from different orga

Question 7

Which of the following is NOT a way to determine the function of annotated genes?

Accepted Answer

A) looking for similar gene sequences of known function 
B) examining the putative protein structure 
C) using gene knockout experiments 
D) finding a pseudogene for that gene 
A) looking for similar gene sequences of known function 
B) examining the putative protein structure 
C) using gene knockout experiments 
D) finding a pseudogene for that gene

Question 8

Which of the following best summarizes what proteomics involves?

Accepted Answer

A) determining protein structure and function 
B) determining protein structure and interactions 
C) determining protein structure, function, location, and interaction 
D) determining protein sequence and interactions 
A) determining protein structure and function 
B) determining protein structure and interactions 
C) determining protein structure, function, location, and interaction 
D) determining protein sequence and interactions

Question 9

How do gene duplication and exon shuffling lead to new genes?

Accepted Answer

Gene duplication results in a second cop

Question 10

Match each of the following terms with its correct definition.
-transcriptome

Accepted Answer

A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome 
A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome

Question 11

What is an open reading frame?

Accepted Answer

A) the nucleotides between and including a start codon and an end codon in all chromosomes 
B) the nucleotides between and including a start codon and an end codon, minus the introns 
C) the nucleotides between and including a start codon and an end codon, minus the exons 
D) the nucleotides between a start codon and end codon only in prokaryotes 
A) the nucleotides between and including a start codon and an end codon in all chromosomes 
B) the nucleotides between and including a start codon and an end codon, minus the introns 
C) the nucleotides between and including a start codon and an end codon, minus the exons 
D) the nucleotides between a start codon and end codon only in prokaryotes

Question 12

Which of the following is NOT an example of a current use of bioinformatics?

Accepted Answer

A) locating individual genes in a genomic sequence 
B) aligning sequences in databases to determine similarities between organisms 
C) predicting the structure and function of gene products 
D) determining the final protein structure of novel proteins based on just the nucleotide sequence 
A) locating individual genes in a genomic sequence 
B) aligning sequences in databases to determine similarities between organisms 
C) predicting the structure and function of gene products 
D) determining the final protein structure of novel proteins based on just the nucleotide sequence

Question 13

There are three types of sequencing described in the text: Sanger (dideoxy) sequencing, whole-genome shotgun sequencing, and Illumin/Solexa sequencing. Which one(s) would be best to use for sequencing a single gene versus an entire genome and why?

Accepted Answer

Single genes can be sequenced using the

Question 14

Match each of the following terms with its correct definition.
-proteomics

Accepted Answer

A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome 
A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome

Question 15

Match the following techniques with the descriptions listed below.
-used to determine DNA sequence in an automated way

Accepted Answer

A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown 
A) whole-genome shotgun sequencing 
B) Illumina/Solexa sequencing 
C) Sanger sequencing 
D) DNA microarray analysis 
E) gene knockout
F)gene knockdown

Question 16

What is the main difference among the studies of genomics, transcriptomics, and proteomics?

Accepted Answer

Genomics is the study of whole genomes a

Question 17

Explain how proteomics is considered by some to be even more important than genome sequencing.

Accepted Answer

There are limits to what genome sequenci

Question 18

During a microarray analysis, cDNAs made from normal cells are stained with a green fluorescent label and cDNAs from abnormal cells are stained with a red fluorescent label. Which of the following statements best summarizes the results of this experiment?

Accepted Answer

A) Red spots indicate genes that are underexpressed in abnormal cells. 
B) Red spots indicate genes that are not expressed in abnormal cells. 
C) Red spots indicate genes that are overexpressed in abnormal cells. 
D) Red spots indicate genes that are overexpressed in normal cells. 
A) Red spots indicate genes that are underexpressed in abnormal cells. 
B) Red spots indicate genes that are not expressed in abnormal cells. 
C) Red spots indicate genes that are overexpressed in abnormal cells. 
D) Red spots indicate genes that are overexpressed in normal cells.

Question 19

What are the relationships among the following types of organisms with respect to genome size: viruses, bacteria, archaea, and eukaryotes?

Accepted Answer

Viruses have the smallest genomes of the

Question 20

Match each of the following terms with its correct definition.
-bioinformatics

Accepted Answer

A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome 
A) all proteins that can be produced by a cell 
B) all transcripts that are produced by a cell 
C) the study of all of the proteins produced from an organism's genome 
D) the study of genome sequences for several organisms 
E) the study of the whole genome of an organism
F)the use of computer programs to extract biological information from sequence data
G)the study of all transcripts produced from an organism's genome

Exam 16: Genomes and Proteomes

Match each of the following terms with its correct definition. -genomics

During a sequencing reaction, the researcher adds all the required components to the reaction, but accidentally adds only one of the four dideoxynucleotides, the ddC. What kinds of products will be observed after this reaction is complete?

Which of the following is NOT added to a single-stranded DNA in order to perform a successful sequencing reaction?

Match the following techniques with the descriptions listed below. -used to replace a normal gene with a defective one to see the effect

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below. -genomics

Comparative genomics is done to learn how genes and genomes have evolved. What are three different concepts that we have learned from comparative genomics?

Which of the following is NOT a way to determine the function of annotated genes?

Which of the following best summarizes what proteomics involves?

How do gene duplication and exon shuffling lead to new genes?

Match each of the following terms with its correct definition. -transcriptome

What is an open reading frame?

Which of the following is NOT an example of a current use of bioinformatics?

There are three types of sequencing described in the text: Sanger (dideoxy) sequencing, whole-genome shotgun sequencing, and Illumin/Solexa sequencing. Which one(s) would be best to use for sequencing a single gene versus an entire genome and why?

Match each of the following terms with its correct definition. -proteomics

Match the following techniques with the descriptions listed below. -used to determine DNA sequence in an automated way

What is the main difference among the studies of genomics, transcriptomics, and proteomics?

Explain how proteomics is considered by some to be even more important than genome sequencing.

During a microarray analysis, cDNAs made from normal cells are stained with a green fluorescent label and cDNAs from abnormal cells are stained with a red fluorescent label. Which of the following statements best summarizes the results of this experiment?

What are the relationships among the following types of organisms with respect to genome size: viruses, bacteria, archaea, and eukaryotes?

Match each of the following terms with its correct definition. -bioinformatics

Light and Life

The Cell: an Overview

Defining Life and Its Origins

Energy and Enzymes

Cell Membranes and Signalling

Cellular Respiration

Photosynthesis

Cell Cycles

Genetic Recombination

Mendel, Genes, and Inheritance

Genes, Chromosomes, and Human Genetics

Dna Structure, Replication, and Organization

Gene Structure and Expression

Control of Gene Expression

Dna Technologies

Evolution: the Development of the Theory

Microevolution: Changes Within Populations

Species and Macroevolution

Understanding the History of Life on Earth

Humans and Evolution

Bacteria and Archaea

Viruses, Viroids, and Prions: Infectious Biological Particles

Protists

Fungi

Plants

Diversity of Animals 1: Sponges, Radiata, Platyhelminthes, and Protostomes

Diversity of Animals 2: Deuterostomes: Vertebrates and Their Closest Relatives

Population Ecology

Population Interactions and Community Ecology

Ecosystems

Conservation of Biodiversity

Putting Selection to Work

Organization of the Plant Body

Transport in Plants

Reproduction and Development in Flowering Plants

Plant Nutrition

Plant Signals and Responses to the Environment

Introduction to Animal Organization and Physiology

Transport in Animals: the Circulatory System

Reproduction in Animals

Animal Development

Control of Animal Processes: Neural Control

Control of Animal Processes: Neural Control

Control of Animal Processes: Neural Integration

Muscles, Skeletons, and Body Movements

Animal Behaviour

Animal Nutrition

Gas Exchange: the Respiratory System

Regulating the Internal Environment

Defences Against Disease

Conservation and Evolutionary Physiology

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