Exam 11: Genes, Chromosomes, and Human Genetics

-In the figure, what type of change in the chromosomes is depicted?

Suppose your cousin finds out that she is a carrier for phenylketonuria. Also suppose that her husband's biological mother has phenylketonuria. She asks you to explain what this could mean if she and her husband have children, and she asks you what, if anything, could be done to best protect any child that they have. What would you tell her?

Prader-Willi syndrome and Angelman syndrome are both caused by the same genetic deletion on human chromosome 15, but they have very different phenotypes. Whether one or the other syndrome occurs depends upon which parent provided the chromosome with the deletion. What is this pattern of inheritance an example of?

What are the two major types of chromosomes in many eukaryotic organisms?

Match each of the following genetic conditions with its mode of inheritance. A mode of inheritance may be used once, more than once, or not at all. -hemophilia A

Suppose that you examine a vial of 100 flies that are all offspring from a single genetic cross. Also suppose that the only females you see present are red-eyed, but the males you see present are both red-eyed and white-eyed. The allele for red eye colour (X^w+) is dominant over the allele for white eye colour (X^w). Which of the following describes the genotypes of the parents?

A woman with which of the following human conditions would exhibit normal physical features?

Match each of the following genetic conditions with its mode of inheritance. A mode of inheritance may be used once, more than once, or not at all. -red-green colour blindness

Which of the following traits determines recombination frequency between two linked genes?

A mutation in the human gene for a fibroblast growth factor receptor (FGFR) is related to cartilage formation. Which disorder does this mutation appear to be responsible for?

Match each of the following genetic conditions with its mode of inheritance. A mode of inheritance may be used once, more than once, or not at all. -cystic fibrosis

Why do carriers for sickle cell anemia have a genetic advantage in some situations over those who are not carriers?

Which genes are subject to cytoplasmic inheritance?

About 10 to 15% of African Americans are carriers of an autosomal recessive genetic disorder in which a defective version of hemoglobin is produced. What is the name of this disorder?

About 4% of people of northern European descent are carriers for an autosomal recessive genetic disorder in which a defective membrane transport protein leads to abnormal chloride levels in extracellular fluids. What is the name of this disorder?

Which scientist was responsible for the characterization of linked genes?

Which term refers to an expression of only one allele of a gene and the silencing of the other allele, all based on which parent contributed each allele?

Match each of the following genetic conditions with its mode of inheritance. A mode of inheritance may be used once, more than once, or not at all. -Huntington disease

Suppose that you are a genetic counsellor, and a man and woman come to you with concerns that if they have a child together, it could have sickle cell anemia. Also suppose that genetic tests reveal that the man and woman are both carriers for sickle cell anemia. Which of the following is the best advice you could give them?