Exam 10: Molecular Biology of the Gene

Dilated cardiomyopathy (DCM) is a common cause of sudden death and heart failure. Many mutations can cause DCM, but several of them are linked to the protein troponin, which is an essential protein that helps regulate muscle contraction in the heart. -The A159E mutation causes an A amino acid to be replaced with an E amino acid (their structures are shown here). What effects do you think the A159E mutation will have on the troponin protein?

-Examine the following two DNA sequences. Sequence 1: ATGCGATGCTAGCAT Sequence 2: ATGCGATGATAGCAT If both of these sequences code for proteins, how might the function of protein 2 differ from the function of protein 1? Use the genetic code shown for assistance.

Which of the following statements about eukaryotic RNA is true?

Bloom syndrome is a rare disease characterized by growth deficiencies, genomic instability, and the early development of cancers. The BLM gene encodes the BLM protein, which when mutated may result in Bloom syndrome. -The BLM protein plays a role in separating DNA molecules during S phase. What molecular process does the BLM protein act on?

Which of the following enzymes catalyzes the production of a strand of RNA from DNA?

HIV does the greatest damage to

Experiments have demonstrated that the "words" of the genetic code (the units that specify amino acids) are

Any change in the nucleotide sequence of DNA is called a

Which of the following statements is false?

Consider the following sentence: "The dog did not eat." Which of the following variations of this sentence is most like a base substitution mutation?

DNA replication

The monomers of DNA and RNA are

Conjugation

Which of the following options best depicts the flow of information when a gene directs the synthesis of a cellular component?

Considering only the steps that take place during translation, which of the following is not needed in order for translation to occur?

In the genetic code

What is the transcription product of the sequence GCTAGCGATGAC?

When a T2 bacteriophage infects an Escherichia coli cell, which part of the phage enters the bacterial cytoplasm?

A friend accidentally sends an email to you that contains a computer virus from his computer. Without knowing it, you infect your computer with the virus when you open the email. This process of spreading the computer virus via email is most like which of the following processes?

Why does a DNA strand grow only in the 5ʹ to 3ʹ direction?