Question 1

C/EBPβ is critical to the second wave of protein synthesis.

Accepted Answer

A) True 
 B)False

Question 2

Alberini's laboratory found that inhibiting protein synthesis (with anisomycin) a few minutes after training did not interfere with retention two days after training but did prevent retention seven and nine days later.

Accepted Answer

A) True 
 B)False

Question 3

Which (statement)s about memory is/are false? (Select all that apply.)

Accepted Answer

A)  CREB deletion impairs LTM. 
B)  Blocking CREB translation impairs STM. 
C)  CREB overexpression can improve LTM under certain conditions. 
D)  Neurons that overexpress CREB do not compete successfully for selection in the neuronal ensemble that supports a fear memory. 
E)  None of the above 
A)  CREB deletion impairs LTM. 
B)  Blocking CREB translation impairs STM. 
C)  CREB overexpression can improve LTM under certain conditions. 
D)  Neurons that overexpress CREB do not compete successfully for selection in the neuronal ensemble that supports a fear memory. 
E)  None of the above

Question 4

If mTOR is inhibited by rapamycin five minutes after avoidance conditioning, memory retention would _______. (Select all that apply.)

Accepted Answer

A)  be impaired at all retention intervals longer than one hour 
B)  be impaired at all retention intervals longer than one day 
C)  not be impaired at any retention interval 
D)  not be impaired if the retention interval is one hour or less. 
E)  None of the above 
A)  be impaired at all retention intervals longer than one hour 
B)  be impaired at all retention intervals longer than one day 
C)  not be impaired at any retention interval 
D)  not be impaired if the retention interval is one hour or less. 
E)  None of the above

Question 5

C/EBPβ's primary role in the autoregulatory loop is to target _______ for transcription

Accepted Answer

The answer of C/EBPβ's primary role in the autoregulatory loop...

Question 6

The second wave of protein synthesis depends on genomic signaling initiated by the BDNF-TrkB pathway.

Accepted Answer

A) True 
 B)False

Question 7

The mTORC2 complex regulates actin polymerization but the mTORC1 complex regulates protein synthesis.

Accepted Answer

A) True 
 B)False

Question 8

The BDNF-TrkB pathway is critical to two waves of protein synthesis.

Accepted Answer

A) True 
 B)False

Question 9

Rapamycin _______ the function of the mTORC1 complex.

Accepted Answer

The answer of Rapamycin _______ the function of the mTORC1...

Question 10

Disrupting either the mTORC1 or the mTORC2 complex will impair the development of long-term memory but have no influence on the formation of short-term memory.

Accepted Answer

A) True 
 B)False

Question 11

If a molecule is critical for long-term memory, it should also be critical for short-term memory.

Accepted Answer

A) True 
 B)False

Question 12

C/EBPβ is a transcription factor.

Accepted Answer

A) True 
 B)False

Question 13

_______ is critical to both the first and second waves of protein synthesis.

Accepted Answer

The answer of _______ is critical to both the first...

Question 14

The mTORC2 complex regulates processes that contribute to the regulation of _______.

Accepted Answer

The answer of The mTORC2 complex regulates processes that contribute...

Question 15

How might sleep contribute to consolidation?

Accepted Answer

The answer of How might sleep contribute to consolidation?...

Question 16

The mTORC1 complex is important to local protein synthesis.

Accepted Answer

A) True 
 B)False

Question 17

Why would one vary the interval separating training and the administration of a protein synthesis inhibitor such as anisomycin?

Accepted Answer

The answer of Why would one vary the interval separating...

Question 18

If the first wave of BDNF protein synthesis is blocked retention at both the one- and seven-day interval will be impaired.

Accepted Answer

A) True 
 B)False

Question 19

Short-term memories are more vulnerable to disruption than long-term memories.

Accepted Answer

A) True 
 B)False

Question 20

According to the text, memory consolidation _______. (Select all that apply.)

Accepted Answer

A)  depends only on the translation of new proteins 
B)  does not require post-translation processes 
C)  is over in about one hour 
D)  can depend on multiple waves of transcription and translation 
E)  None of the above 
A)  depends only on the translation of new proteins 
B)  does not require post-translation processes 
C)  is over in about one hour 
D)  can depend on multiple waves of transcription and translation 
E)  None of the above

C/EBPβ is critical to the second wave of protein synthesis.

Alberini's laboratory found that inhibiting protein synthesis (with anisomycin) a few minutes after training did not interfere with retention two days after training but did prevent retention seven and nine days later.

Which (statement)s about memory is/are false? (Select all that apply.)

If mTOR is inhibited by rapamycin five minutes after avoidance conditioning, memory retention would _______. (Select all that apply.)

C/EBPβ's primary role in the autoregulatory loop is to target _______ for transcription

The second wave of protein synthesis depends on genomic signaling initiated by the BDNF-TrkB pathway.

The mTORC2 complex regulates actin polymerization but the mTORC1 complex regulates protein synthesis.

The BDNF-TrkB pathway is critical to two waves of protein synthesis.

Rapamycin _______ the function of the mTORC1 complex.

Disrupting either the mTORC1 or the mTORC2 complex will impair the development of long-term memory but have no influence on the formation of short-term memory.

If a molecule is critical for long-term memory, it should also be critical for short-term memory.

C/EBPβ is a transcription factor.

_______ is critical to both the first and second waves of protein synthesis.

The mTORC2 complex regulates processes that contribute to the regulation of _______.

How might sleep contribute to consolidation?

The mTORC1 complex is important to local protein synthesis.

Why would one vary the interval separating training and the administration of a protein synthesis inhibitor such as anisomycin?

If the first wave of BDNF protein synthesis is blocked retention at both the one- and seven-day interval will be impaired.

Short-term memories are more vulnerable to disruption than long-term memories.

According to the text, memory consolidation _______. (Select all that apply.)

Introduction: Fundamental Concepts and Historical Foundations

Memory and the Brain: Central Concepts

Generating Long-Term Potentiation

Stabilizing Long-Term Potentiation

Consolidating Ltp: Translation and Transcription

Consolidating Ltp: Specific Mechanisms

Maintaining Long-Term Potentiation

Bringing It All Together

Making Memories: Conceptual Issues and Methodologies

Memory Formation: Early Stages

Memory Modulation Systems

The Yin and Yang of Memory: Forgetting Versus Maintenance

Hunting for Engrams

The Fate of Retrieved Memories

Memory Systems and the Hippocampus

The Hippocampus Index and Episodic Memory

When Memories Age

Actions, Habits, and the Cortico-Striatal System

Learning About Danger: the Neurobiology of Fear Memories

Filters

Exam 11: Memory Consolidation

C/EBPβ is critical to the second wave of protein synthesis.

Alberini's laboratory found that inhibiting protein synthesis (with anisomycin) a few minutes after training did not interfere with retention two days after training but did prevent retention seven and nine days later.

Which (statement)s about memory is/are false? (Select all that apply.)

If mTOR is inhibited by rapamycin five minutes after avoidance conditioning, memory retention would _______. (Select all that apply.)

C/EBPβ's primary role in the autoregulatory loop is to target _______ for transcription

The second wave of protein synthesis depends on genomic signaling initiated by the BDNF-TrkB pathway.

The mTORC2 complex regulates actin polymerization but the mTORC1 complex regulates protein synthesis.

The BDNF-TrkB pathway is critical to two waves of protein synthesis.

Rapamycin _______ the function of the mTORC1 complex.

Disrupting either the mTORC1 or the mTORC2 complex will impair the development of long-term memory but have no influence on the formation of short-term memory.

If a molecule is critical for long-term memory, it should also be critical for short-term memory.

C/EBPβ is a transcription factor.

_______ is critical to both the first and second waves of protein synthesis.

The mTORC2 complex regulates processes that contribute to the regulation of _______.

How might sleep contribute to consolidation?

The mTORC1 complex is important to local protein synthesis.

Why would one vary the interval separating training and the administration of a protein synthesis inhibitor such as anisomycin?

If the first wave of BDNF protein synthesis is blocked retention at both the one- and seven-day interval will be impaired.

Short-term memories are more vulnerable to disruption than long-term memories.

According to the text, memory consolidation _______. (Select all that apply.)

Introduction: Fundamental Concepts and Historical Foundations

Memory and the Brain: Central Concepts

Generating Long-Term Potentiation

Stabilizing Long-Term Potentiation

Consolidating Ltp: Translation and Transcription

Consolidating Ltp: Specific Mechanisms

Maintaining Long-Term Potentiation

Bringing It All Together

Making Memories: Conceptual Issues and Methodologies

Memory Formation: Early Stages

Memory Modulation Systems

The Yin and Yang of Memory: Forgetting Versus Maintenance

Hunting for Engrams

The Fate of Retrieved Memories

Memory Systems and the Hippocampus

The Hippocampus Index and Episodic Memory

When Memories Age

Actions, Habits, and the Cortico-Striatal System

Learning About Danger: the Neurobiology of Fear Memories

Filters