Exam 24: Immunity and Host Defense

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If you were given a new necklace and developed reddening,swelling,and itching of your skin around your neck 24 hours after putting on the necklace,what reason would you give to this phenomenon? What immune cells are involved?

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This is a case of delayed-type hypersensitivity (DTH)or type IV hypersensitivity.Chemical constituents of the jewelry are covalently binding to your skin proteins and creating new antigens to elicit a DTH response known as contact dermatitis.The immune cells involved are the TH cells.These cells produce an inflammatory response that causes localized tissue damage,pain,blistering,and itching.

What is the drawback of live attenuated vaccines?

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D

An example of pathogen-associated molecular patterns (PAMP)is

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C

A recombinant-vector virus would still be effective if the vaccinia virus is unable to express the cloned gene as an antigenic protein.

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Which is an example of acquisition of natural passive immunity?

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TH₂ cells interact directly with the pathogens.

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All gram-negative bacteria have lipopolysaccharides in their outer membranes.

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DNA vaccines are bacterial plasmids that contain cloned DNA with an antigen of interest are unlike attenuated vaccines because there is no chance of causing disease.

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After the first exposure to an antigen,a ________ stimulates growth and multiplication of antigen-reaction cells.

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In Hashimotos's disease,autoantibodies are made against ________,a product of the thyroid gland.

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Cells that can engulf foreign particles,and can ingest,kill,and digest most bacterial pathogens are called

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Compare and contrast the origin and roles of B cells and T cells.

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DiGeorge's syndrome is a developmental defect that prevents the maturation of the thymus.What cell type would be reduced by this condition?

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In adaptive immunity,pathogen specific receptors are produced in large numbers only after exposure to the pathogen or its products.

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Which of these is often used as a prophylactic measure to protect a person against future attack by a pathogen?

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A woman is being treated for systemic lupus erythematosus (SLE).She has an increased risk of opportunistic infections.Based on what you know about SLE and the treatment for it,propose why she has an increased risk of opportunistic infections.

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Which of the following is NOT an autoimmune disease?

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T cells interact with the peptide-MHC complex using

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Infants acquire natural passive immunity from maternal antibodies transferred across the placenta or in breast milk.

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The inflammatory cytokines IL-1,IL-6,and TNF-α are also

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