Question 1

The preferred method for detection of T.gondii is:

Accepted Answer

A)  culture. 
B)  ELISA. 
C)  IFA. 
D)  PCR. 
A)  culture. 
B)  ELISA. 
C)  IFA. 
D)  PCR. B

Question 2

Symptoms of acquired T.gondii infection can:

Accepted Answer

A)  be mild. 
B)  resemble infectious mononucleosis. 
C)  cause a urinary tract infection. 
D)  both a and b 
A)  be mild. 
B)  resemble infectious mononucleosis. 
C)  cause a urinary tract infection. 
D)  both a and b D

Question 3

After IgM-positive sera undergo confirmatory testing,the results are interpreted as a(n):

Accepted Answer

A)  recently acquired infection. 
B)  infection acquired in the past. 
C)  false-positive test result. 
D)  all of the above. 
A)  recently acquired infection. 
B)  infection acquired in the past. 
C)  false-positive test result. 
D)  all of the above. D

Question 4

The PCR assay for T.gondii can be performed on:

Accepted Answer

A)  serum or plasma. 
B)  fresh or frozen biopsy tissue. 
C)  cerebrospinal fluid. 
D)  all of the above. 
A)  serum or plasma. 
B)  fresh or frozen biopsy tissue. 
C)  cerebrospinal fluid. 
D)  all of the above.

Question 5

The Centers for Disease Control and Prevention (CDC)suggests that any confirmed equivocal or ____________ test results for toxoplasmosis should be retested using a different assay.

Accepted Answer

A)  positive 
B)  negative 
C)  questionable 
D)  prenatal 
A)  positive 
B)  negative 
C)  questionable 
D)  prenatal

Question 6

Major sources of increasing human infection with T.gondii include all the following except:

Accepted Answer

A)  fecal contamination of food with the T.gondii organism. 
B)  infected meat. 
C)  bloody body fluids. 
D)  raw infected milk. 
A)  fecal contamination of food with the T.gondii organism. 
B)  infected meat. 
C)  bloody body fluids. 
D)  raw infected milk.

Question 7

The best evidence of toxoplasmosis infection is a significant change in:

Accepted Answer

A)  two appropriately timed specimens. 
B)  acute and convalescent specimens. 
C)  two appropriate specimens analyzed at the same time in the laboratory. 
D)  all of the above. 
A)  two appropriately timed specimens. 
B)  acute and convalescent specimens. 
C)  two appropriate specimens analyzed at the same time in the laboratory. 
D)  all of the above.

Question 8

Toxoplasma-infected mothers who are not treated can give birth to a(n):

Accepted Answer

A)  less than term infant. 
B)  underweight infant. 
C)  congenitally infected infant. 
D)  normal,healthy infant. 
A)  less than term infant. 
B)  underweight infant. 
C)  congenitally infected infant. 
D)  normal,healthy infant.

Question 9

IgM antibodies to T.gondii in an adult are an indication of:

Accepted Answer

A)  current or recent infection. 
B)  chronic infection. 
C)  past infection. 
D)  antibody transmitted from another person. 
A)  current or recent infection. 
B)  chronic infection. 
C)  past infection. 
D)  antibody transmitted from another person.

Question 10

The avidity result is determined using:

Accepted Answer

A)  ratios of antibody titration curves of urea-treated and untreated sera. 
B)  titers of antibody in preinfection and postinfection specimens. 
C)  amniotic fluid versus serum. 
D)  both b and c 
A)  ratios of antibody titration curves of urea-treated and untreated sera. 
B)  titers of antibody in preinfection and postinfection specimens. 
C)  amniotic fluid versus serum. 
D)  both b and c

Question 11

All mammals can transmit T.gondii by:

Accepted Answer

A)  casual contact. 
B)  transplacental transmission. 
C)  sexual contact. 
D)  none of the above. 
A)  casual contact. 
B)  transplacental transmission. 
C)  sexual contact. 
D)  none of the above.

Question 12

The definitive host of Toxoplasma gondii is the:

Accepted Answer

A)  dog. 
B)  house cat. 
C)  chicken. 
D)  rodent class. 
A)  dog. 
B)  house cat. 
C)  chicken. 
D)  rodent class.

Question 13

Toxoplasma gondii antibody assay can demonstrate antibodies within __________ after infection.

Accepted Answer

A)  2 days 
B)  1 week 
C)  2 weeks 
D)  1 month 
A)  2 days 
B)  1 week 
C)  2 weeks 
D)  1 month

Question 14

Transfusion-transmitted toxoplasmosis is associated with:

Accepted Answer

A)  packed red blood cells. 
B)  platelet concentrates. 
C)  leukocyte concentrates. 
D)  either b or c 
A)  packed red blood cells. 
B)  platelet concentrates. 
C)  leukocyte concentrates. 
D)  either b or c

Question 15

Any positive result in a pregnant patient confirmed as positive by a second reference laboratory should be evaluated by:

Accepted Answer

A)  amniocentesis testing by PCR for T.gondii. 
B)  IgM,IgA,and IgE ELISAs. 
C)  Sabin-Feldman dye test (IgG). 
D)  IgE immunosorbent agglutination assay. 
A)  amniocentesis testing by PCR for T.gondii. 
B)  IgM,IgA,and IgE ELISAs. 
C)  Sabin-Feldman dye test (IgG). 
D)  IgE immunosorbent agglutination assay.

Question 16

Congenital toxoplasmosis can result in:

Accepted Answer

A)  central nervous system (CNS)malformation. 
B)  prenatal mortality. 
C)  congenital heart defects. 
D)  both a and b 
A)  central nervous system (CNS)malformation. 
B)  prenatal mortality. 
C)  congenital heart defects. 
D)  both a and b

Exam 20: Toxoplasmosis

The preferred method for detection of T.gondii is:

Symptoms of acquired T.gondii infection can:

After IgM-positive sera undergo confirmatory testing,the results are interpreted as a(n):

The PCR assay for T.gondii can be performed on:

The Centers for Disease Control and Prevention (CDC)suggests that any confirmed equivocal or ____________ test results for toxoplasmosis should be retested using a different assay.

Major sources of increasing human infection with T.gondii include all the following except:

The best evidence of toxoplasmosis infection is a significant change in:

Toxoplasma-infected mothers who are not treated can give birth to a(n):

IgM antibodies to T.gondii in an adult are an indication of:

The avidity result is determined using:

All mammals can transmit T.gondii by:

The definitive host of Toxoplasma gondii is the:

Toxoplasma gondii antibody assay can demonstrate antibodies within __________ after infection.

Transfusion-transmitted toxoplasmosis is associated with:

Any positive result in a pregnant patient confirmed as positive by a second reference laboratory should be evaluated by:

Congenital toxoplasmosis can result in:

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Hypersensitivity Reactions

Immunoproliferative Disorders

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Tumor Immunology

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