Question 1

11.Many genetic diseases are caused by mutations that affect RNA __________.

Accepted Answer

splicing

Question 2

The carboxyl-terminal domain (CTD)of RNA polymerase II is involved in

Accepted Answer

A)  binding to promoter regions of DNA. 
B)  formation of the transcription bubble. 
C)  coordinating post-transcriptional processing events. 
D)  recognition of the termination signal. 
E)  None of the answers is correct. 
A)  binding to promoter regions of DNA. 
B)  formation of the transcription bubble. 
C)  coordinating post-transcriptional processing events. 
D)  recognition of the termination signal. 
E)  None of the answers is correct. C

Question 3

13.A _______________ sequence is determined by an alignment of multiple DNA base sequences and is a recurring pattern or motif.

Accepted Answer

consensus

Question 4

17.The rate of RNA synthesis in E.coli is approximately _______________ nucleotides per second.

Accepted Answer

The answer of 17.The rate of RNA synthesis in E.coli...

Question 5

Where are enhancer sequences found in the gene?

Accepted Answer

Enhancers can be found upstrea

Question 6

Functions of RNA polymerase include

Accepted Answer

A)  searching for promoter sites. 
B)  unwinding short stretches of DNA. 
C)  detecting termination signals. 
D)  All the answers are correct. 
E)  searching for promoter sites and detecting termination signals. 
A)  searching for promoter sites. 
B)  unwinding short stretches of DNA. 
C)  detecting termination signals. 
D)  All the answers are correct. 
E)  searching for promoter sites and detecting termination signals.

Question 7

What name is given to the region of RNA synthesis that contains the DNA,RNA,and RNA polymerase?

Accepted Answer

A)  transcription fork 
B)  replicon 
C)  transcriptosome 
D)  transcription bubble 
E)  transcription complex 
A)  transcription fork 
B)  replicon 
C)  transcriptosome 
D)  transcription bubble 
E)  transcription complex

Question 8

Describe some of the significant differences between eukaryotic and prokaryotic transcription and translation.

Accepted Answer

In eukaryotes,the two processes are sepa

Question 9

tRNA and rRNA modification in prokaryotes includes

Accepted Answer

A)  cleavage and modification of nascent RNA. 
B)  addition of nucleotides. 
C)  spliceosome-mediated splicing of the nascent RNA. 
D)  All the answers are correct. 
E)  cleavage and modification of nascent RNA and addition of nucleotides. 
A)  cleavage and modification of nascent RNA. 
B)  addition of nucleotides. 
C)  spliceosome-mediated splicing of the nascent RNA. 
D)  All the answers are correct. 
E)  cleavage and modification of nascent RNA and addition of nucleotides.

Question 10

12.There are approximately _______________ promoter sites found in the E.coli genome.

Accepted Answer

The answer of 12.There are approximately _______________ promoter sites found...

Question 11

How does RNA polymerase find the proper binding site?

Accepted Answer

The RNA polymerase b

Question 12

What is a common feature of both protein-dependent and protein-independent termination signals in transcription?

Accepted Answer

The signals that mediate termi

Question 13

The first event in eukaryotic transcriptional activation is binding of

Accepted Answer

A)  the TATA-box-binding protein (TBP) to the TATA box. 
B)  the SP-1 protein to the CAAT box. 
C)  the RNA polymerase 500 base pairs upstream of the CAAT and TATA boxes. 
D)  rho protein to DNA. 
E)  None of the answers is correct. 
A)  the TATA-box-binding protein (TBP) to the TATA box. 
B)  the SP-1 protein to the CAAT box. 
C)  the RNA polymerase 500 base pairs upstream of the CAAT and TATA boxes. 
D)  rho protein to DNA. 
E)  None of the answers is correct.

Question 14

Approximately how many mRNA transcripts in higher eukaryotes undergo processing?

Accepted Answer

Nearly all mRNA prec

Question 15

What are the two types of self-splicing introns?

Accepted Answer

They are divided into group I and group

Question 16

Which of the following is a mechanism of splicing that allows diversity in the proteins generated from a particular gene?

Accepted Answer

A)  crossover 
B)  mRNA recombination 
C)  recombinase-assisted splicing 
D)  translocation 
E)  alternative splicing 
A)  crossover 
B)  mRNA recombination 
C)  recombinase-assisted splicing 
D)  translocation 
E)  alternative splicing

Question 17

What is the significance of the $\sigma$subunit?

Accepted Answer

The @#LAT-DLM& subunit contributes to initiation i

Question 18

A disease caused by mutations in pre-mRNA or in the splicing factors is

Accepted Answer

A)  Burkitt lymphoma. 
B)  thalassemia. 
C)  retinitis pigmentosa. 
D)  sickle-cell anemia. 
E)  None of the answers is correct. 
A)  Burkitt lymphoma. 
B)  thalassemia. 
C)  retinitis pigmentosa. 
D)  sickle-cell anemia. 
E)  None of the answers is correct.

Question 19

What term is used to describe the synthesis of RNA?

Accepted Answer

A)  replication 
B)  splicing 
C)  translation 
D)  transcription 
E)  None of the answers is correct. 
A)  replication 
B)  splicing 
C)  translation 
D)  transcription 
E)  None of the answers is correct.

Question 20

20.RNA self-splicing demonstrates the role of RNA as a __________________.

Accepted Answer

The answer of 20.RNA self-splicing demonstrates the role of RNA...

Exam 29: RNA Synthesis and Processing

11.Many genetic diseases are caused by mutations that affect RNA __________.

The carboxyl-terminal domain (CTD)of RNA polymerase II is involved in

13.A _______________ sequence is determined by an alignment of multiple DNA base sequences and is a recurring pattern or motif.

17.The rate of RNA synthesis in E.coli is approximately _______________ nucleotides per second.

Where are enhancer sequences found in the gene?

Functions of RNA polymerase include

What name is given to the region of RNA synthesis that contains the DNA,RNA,and RNA polymerase?

Describe some of the significant differences between eukaryotic and prokaryotic transcription and translation.

tRNA and rRNA modification in prokaryotes includes

12.There are approximately _______________ promoter sites found in the E.coli genome.

How does RNA polymerase find the proper binding site?

What is a common feature of both protein-dependent and protein-independent termination signals in transcription?

The first event in eukaryotic transcriptional activation is binding of

Approximately how many mRNA transcripts in higher eukaryotes undergo processing?

What are the two types of self-splicing introns?

Which of the following is a mechanism of splicing that allows diversity in the proteins generated from a particular gene?

What is the significance of the σ\sigmaσ subunit?

A disease caused by mutations in pre-mRNA or in the splicing factors is

What term is used to describe the synthesis of RNA?

20.RNA self-splicing demonstrates the role of RNA as a __________________.

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, repair, and Recombination

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters

What is the significance of the $\sigma$ subunit?