Exam 4: Nucleic Acids

Draw the two forms of a phosphodiester bond that can occur under physiological pH.If the pK_a for this conversion is 6.2,what form predominates in the lysosome where the pH is about 5?

Which of the following is correctly paired with the type of tautomerization(s)that occurs?

Base stacking,or the "stacking interaction," is most likely the result of which noncovalent interaction

Which of the following techniques was used to determine the double helical structure of DNA?

Which of the following bases is found only in DNA?

While RNA is often single stranded,transfer RNA (tRNA)is usually found with some double stranded structure.Which of the following explains this?

Which of the following correctly describes the structure of a nucleotide?

Which of the following is correctly paired?

Which of the following describes the directionality seen in nucleic acids?

The following shows deoxyadenosine in the _____ conformation

Which of the following represents a palindromic sequence?

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

Where are G-quadruplexes most commonly found?

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Which of the following secondary structures is correctly identified?

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

From the following polynucleotide sequence,one would conclude which of the following? ACCAGTCG

Based on the following,which is true regarding the acid/base properties of guanine?

Which of the following is a major difference between B-DNA and A-DNA?

Which of the following is correct regarding the flow of genetic information?