Question 1

Based on the following,what can be said about the synthesis of polynucleotides?

Accepted Answer

A) polynucleotides are unstable and are rapidly degraded 
B) polynucleotide formation is made much more exergonic by the hydrolysis of pyrophosphate 
C) the hydrolysis of nucleoside triphosphates is the only driving force to make an overall irreversible reaction 
D) polynucleotides are highly resistant to hydrolysis,even in the presence of an acid catalyst 
E) none of the above 
A) polynucleotides are unstable and are rapidly degraded 
B) polynucleotide formation is made much more exergonic by the hydrolysis of pyrophosphate 
C) the hydrolysis of nucleoside triphosphates is the only driving force to make an overall irreversible reaction 
D) polynucleotides are highly resistant to hydrolysis,even in the presence of an acid catalyst 
E) none of the above

Question 2

Draw the structure of cytosine and thymine,then show the most common tautomer of each.

Accepted Answer

The answer of Draw the structure of cytosine and thymine,then...

Question 3

Replication of DNA is best considered __________.

Accepted Answer

A) conservative 
B) semiconservative 
C) dispersive 
D) complementary 
E) none of the above 
A) conservative 
B) semiconservative 
C) dispersive 
D) complementary 
E) none of the above

Question 4

In the Watson-Crick DNA model,how many base pairs are found in one turn of the helix?

Accepted Answer

A) 4 
B) 6 
C) 8 
D) 10 
E) 12 
A) 4 
B) 6 
C) 8 
D) 10 
E) 12

Question 5

Which of the following types of DNA are often supercoiled?

Accepted Answer

A) extremely long linear DNA,such as seen in human chromosomes 
B) very short linear DNA 
C) circular DNA 
D) DNA molecules that contain both circular and linear regions 
E) all of the above 
A) extremely long linear DNA,such as seen in human chromosomes 
B) very short linear DNA 
C) circular DNA 
D) DNA molecules that contain both circular and linear regions 
E) all of the above

Question 6

Which of the following best explains why the ratios of A/T and G/C are 0.77 and 1.08,respectively in bacteriophage $\phi$X174?

Accepted Answer

A) the base pairing in bacteriophages is not always A-T and C-G 
B) studies done with most bacteriophages do not use complete genomic DNA due to the inherent instability of phage DNA 
C) bacteriophage DNA often uses bases other than A,T,C and G 
D) many viruses often use single stranded DNA 
E) none of the above 
A) the base pairing in bacteriophages is not always A-T and C-G 
B) studies done with most bacteriophages do not use complete genomic DNA due to the inherent instability of phage DNA 
C) bacteriophage DNA often uses bases other than A,T,C and G 
D) many viruses often use single stranded DNA 
E) none of the above

Question 7

In a circular DNA molecule of 126 bp with 10.5 bp/turn,which of the following represents an unstrained circle? (L = linking number,T = twist and W = writhe)

Accepted Answer

A) L = 12,T = 12,W = 0 
B) L = 11,T = 11,W = 0 
C) L = 11,T = 12,W = -1 
D) L = 12,T = 11,W = +1 
E) L = 11,T = 10,W = 0 
A) L = 12,T = 12,W = 0 
B) L = 11,T = 11,W = 0 
C) L = 11,T = 12,W = -1 
D) L = 12,T = 11,W = +1 
E) L = 11,T = 10,W = 0

Based on the following,what can be said about the synthesis of polynucleotides?

Draw the structure of cytosine and thymine,then show the most common tautomer of each.

Replication of DNA is best considered __________.

In the Watson-Crick DNA model,how many base pairs are found in one turn of the helix?

Which of the following types of DNA are often supercoiled?

Which of the following best explains why the ratios of A/T and G/C are 0.77 and 1.08,respectively in bacteriophage $\phi$ X174?

In a circular DNA molecule of 126 bp with 10.5 bp/turn,which of the following represents an unstrained circle? (L = linking number,T = twist and W = writhe)

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars,saccharides,glycans

Lipids,membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, gluconeogenesis, glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids,triacylglycerols,and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, steroids, isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, utilization, and Turnover

Metabolism of Nitogenous Compounds Ii: Amino Acids, porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes,genomes and Chromosomes

Dna Replication

Dna Restructuring: Repair,recombination,rearrangement,amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

Exam 4: Nucleic Acids

Based on the following,what can be said about the synthesis of polynucleotides?

Draw the structure of cytosine and thymine,then show the most common tautomer of each.

Replication of DNA is best considered __________.

In the Watson-Crick DNA model,how many base pairs are found in one turn of the helix?

Which of the following types of DNA are often supercoiled?

Which of the following best explains why the ratios of A/T and G/C are 0.77 and 1.08,respectively in bacteriophage ϕ\phiϕ X174?

In a circular DNA molecule of 126 bp with 10.5 bp/turn,which of the following represents an unstrained circle? (L = linking number,T = twist and W = writhe)

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars,saccharides,glycans

Lipids,membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, gluconeogenesis, glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids,triacylglycerols,and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, steroids, isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, utilization, and Turnover

Metabolism of Nitogenous Compounds Ii: Amino Acids, porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes,genomes and Chromosomes

Dna Replication

Dna Restructuring: Repair,recombination,rearrangement,amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

Which of the following best explains why the ratios of A/T and G/C are 0.77 and 1.08,respectively in bacteriophage $\phi$ X174?