Exam 22: Nucleotide Metabolism

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Show the reaction of allopurinol with xanthine dehydrogenase and explain how this molecule functions as an inhibitor of the enzyme. Show the reaction of allopurinol with xanthine dehydrogenase and explain how this molecule functions as an inhibitor of the enzyme.

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The ten enzyme activities that convert PRPP to inosinic acid are part of a multienzyme complex known as the _________.

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During the conversion of IMP to GMP and AMP,__________ serves as the nitrogen source for GMP,while _________ serves as the nitrogen source for AMP.

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Given the structure of GMP,indicate the source for all carbons and nitrogens in the guanine base. Given the structure of GMP,indicate the source for all carbons and nitrogens in the guanine base.

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