Question 1

What GTP-binding protein is associated with the formation of the COPI coat on COPI-coated vesicles?

Accepted Answer

A) Sar1 
B) Arf Arf 
C) ARF1 (adenosylation ribose factor) 
D) Ras 
E) Src 
A) Sar1 
B) Arf Arf 
C) ARF1 (adenosylation ribose factor) 
D) Ras 
E) Src

Question 2

What sugar is usually removed from the N-linked core oligosaccharide chains on proteins in the Golgi complex as opposed to the glucose residues trimmed off in the ER?

Accepted Answer

A) glucose 
B) galactose 
C) mannose 
D) sialic acid 
E) fucose 
A) glucose 
B) galactose 
C) mannose 
D) sialic acid 
E) fucose

Question 3

Which list below names the compartments into which chloroplast proteins must be imported?

Accepted Answer

A) inner and outer chloroplast membranes,the intermembrane space,the stroma,thylakoid membranes,thylakoid lumen 
B) inner and outer chloroplast membranes,the intercristal space,the stroma,thylakoid membranes,thylakoid lumen 
C) inner and outer chloroplast membranes,the intermembrane space,the cytoplasm,thylakoid membranes,thylakoid lumen 
D) inner and medial chloroplast membranes,the intermembrane space,the stroma,thylakoid membranes,thylakoid lumen 
E) inner and outer chloroplast membranes,the intermembrane space,the stroma,cristae membranes,thylakoid lumen 
A) inner and outer chloroplast membranes,the intermembrane space,the stroma,thylakoid membranes,thylakoid lumen 
B) inner and outer chloroplast membranes,the intercristal space,the stroma,thylakoid membranes,thylakoid lumen 
C) inner and outer chloroplast membranes,the intermembrane space,the cytoplasm,thylakoid membranes,thylakoid lumen 
D) inner and medial chloroplast membranes,the intermembrane space,the stroma,thylakoid membranes,thylakoid lumen 
E) inner and outer chloroplast membranes,the intermembrane space,the stroma,cristae membranes,thylakoid lumen

Question 4

Which protein(s)below is(are)recruited to the COPII coat by Sar1-GTP?

Accepted Answer

A) ARF1 
B) Sec23 
C) Sec32 
D) Sec24 
E) both Sec23 and Sec24 
A) ARF1 
B) Sec23 
C) Sec32 
D) Sec24 
E) both Sec23 and Sec24

Question 5

Why does glucocerebrosidase taken into macrophages by receptor-mediated endocytosis end up in lysosomes?

Accepted Answer

A) The enzyme travels through the cytoplasm to get to lysosomes. 
B) The enzyme denatures and then goes through a channel into lysosomes. 
C) Lysosomes are the natural target of enzymes taken into macrophages by endocytosis. 
D) Lysosomes adsorb glucocerebrosidase to their surfaces. 
E) Lysosomes pick up the enzyme from mitochondria. 
A) The enzyme travels through the cytoplasm to get to lysosomes. 
B) The enzyme denatures and then goes through a channel into lysosomes. 
C) Lysosomes are the natural target of enzymes taken into macrophages by endocytosis. 
D) Lysosomes adsorb glucocerebrosidase to their surfaces. 
E) Lysosomes pick up the enzyme from mitochondria.

Question 6

What recognizes ubiquitinated signaling receptors and sorts them into the membranes that give rise to the internal vesicles of the late endosomes?

Accepted Answer

A) ESCRT complexes 
B) CREST complexes 
C) ESCORT complexes 
D) RESCT complexes 
E) lysosomes 
A) ESCRT complexes 
B) CREST complexes 
C) ESCORT complexes 
D) RESCT complexes 
E) lysosomes

Question 7

What determines the function of a cell's smooth endoplasmic reticulum?

Accepted Answer

A) its lipid content 
B) its polynucleotide content 
C) its carbohydrate content 
D) its protein content 
E) its age 
A) its lipid content 
B) its polynucleotide content 
C) its carbohydrate content 
D) its protein content 
E) its age

Question 8

How is the orientation of membrane proteins in the membrane thought to be accomplished?

Accepted Answer

A) After synthesis,an enzyme orients the protein properly. 
B) During synthesis,the translocon inner lining orients the nascent polypeptide so the more positive end faces the cytosol. 
C) During synthesis,the translocon inner lining orients the nascent polypeptide so the more negative end faces the cytosol. 
D) During synthesis,the translocon inner lining orients the nascent polypeptide so the more positive end faces the mitochondrial intermembrane space. 
E) After synthesis,the translocon inner lining orients the nascent polypeptide so the more positive end faces the cytosol. 
A) After synthesis,an enzyme orients the protein properly. 
B) During synthesis,the translocon inner lining orients the nascent polypeptide so the more positive end faces the cytosol. 
C) During synthesis,the translocon inner lining orients the nascent polypeptide so the more negative end faces the cytosol. 
D) During synthesis,the translocon inner lining orients the nascent polypeptide so the more positive end faces the mitochondrial intermembrane space. 
E) After synthesis,the translocon inner lining orients the nascent polypeptide so the more positive end faces the cytosol.

Question 9

The outer and inner chloroplast membranes contain distinct translocation complexes named ________,respectively,that work together during protein import.

Accepted Answer

A) Toc and Tic complexes 
B) Tic and Toc complexes 
C) Tick and Tock complexes 
D) Tock and Tick complexes 
E) Tock and Tic complexes 
A) Toc and Tic complexes 
B) Tic and Toc complexes 
C) Tick and Tock complexes 
D) Tock and Tick complexes 
E) Tock and Tic complexes

Question 10

The three-legged assembly of protein chains that makes up a clathrin molecule and that can assemble into a network of polygons resembling a honeycomb is called a(n)_____.

Accepted Answer

A) trigeminy 
B) triskeleton 
C) trigellium 
D) triskelion 
E) triskellium 
A) trigeminy 
B) triskeleton 
C) trigellium 
D) triskelion 
E) triskellium

Question 11

What happens if misfolded proteins are generated in the ER at a faster rate than they can be exported to the cytoplasm?

Accepted Answer

A) They are degraded in the ER. 
B) They are inserted into the ER membrane. 
C) They are resynthesized in the ER. 
D) They accumulate in the ER. 
E) They accumulate in the Golgi complex. 
A) They are degraded in the ER. 
B) They are inserted into the ER membrane. 
C) They are resynthesized in the ER. 
D) They accumulate in the ER. 
E) They accumulate in the Golgi complex.

Question 12

TB 8.008 Elevated temperatures at which temperature-sensitive mutants do not work are called ________ temperatures.

Accepted Answer

A) restrictive 
B) permissive 
C) temperature-sensitive 
D) frame-shift 
E) point 
A) restrictive 
B) permissive 
C) temperature-sensitive 
D) frame-shift 
E) point

Question 13

In general,diseases that result from a deficiency of a single lysosomal enzyme are called ________.

Accepted Answer

A) lysosomal dissociation disorders 
B) Tay-Sachs Disease 
C) lysosomal storage disorders 
D) ancestral disorders 
E) ancestral lysosomal disorders 
A) lysosomal dissociation disorders 
B) Tay-Sachs Disease 
C) lysosomal storage disorders 
D) ancestral disorders 
E) ancestral lysosomal disorders

Question 14

You are studying the effects of a number of treatments on the nervous system of a particular species of lab animal.One of the treatments is able to block the process of autophagy and it can be administered with enough precision to localize the treatment to a particular portion of the brain.What effect does such a treatment have on the animal's brain and what do the results suggest?

Accepted Answer

When treated in this fashion,the specifi

Question 15

What is thought to mediate the initial contacts between a transport vesicle and its target membrane,like a Golgi cisterna? Describe the two groups of tethering proteins.

Accepted Answer

The initial contacts between a transport

Question 16

A scientist is studying the movement of vesicles between different cellular compartments.She starts by treating the cells with a number of known inhibitors of cellular activities.One of them greatly increases the number of fuzzy-coated vesicles.What is a possible explanation? The effect of the inhibitor can be reversed if intracellular GTP is added in large amounts.What might explain this?

Accepted Answer

The inhibitor could inhibit some action

Question 17

The endomembrane system when homogenized is broken up into vesicles,which are heterogeneous but similar in size.These vesicles can be purified and,after purification,often retain their biological activity.They are collectively referred to as _________.

Accepted Answer

A) endosomes 
B) microsomes 
C) ribosomes 
D) minisomes 
E) lysosomes 
A) endosomes 
B) microsomes 
C) ribosomes 
D) minisomes 
E) lysosomes

Question 18

What do studies suggest governs the "decision" to destroy a defective protein that has been unable to fold correctly and has been in the ER for an extended period of time?

Accepted Answer

A) a fast-acting ER enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
B) a slow-acting ER enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
C) a fast-acting cytoplasmic enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
D) a slow-acting nuclear enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
E) a slow-acting cytoplasmic enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
A) a fast-acting ER enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
B) a slow-acting ER enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
C) a fast-acting cytoplasmic enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
D) a slow-acting nuclear enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein 
E) a slow-acting cytoplasmic enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein

Question 19

Which of the proteins below is(are)not made on the membrane-bound ribosomes of the RER?

Accepted Answer

A) peripheral proteins of the inner surface of the plasma membrane 
B) soluble lysosomal proteins 
C) vacuolar enzymes 
D) proteins of the extracellular matrix 
E) All of these are correct. 
A) peripheral proteins of the inner surface of the plasma membrane 
B) soluble lysosomal proteins 
C) vacuolar enzymes 
D) proteins of the extracellular matrix 
E) All of these are correct.

Question 20

Which coated vesicles move materials in a retrograde direction from the ERGIC and Golgi stack backwards toward the ER?

Accepted Answer

A) COPII-coated vesicles 
B) COPI-coated vesicles 
C) clathrin-coated vesicles 
D) cadmium-coated vesicles 
E) both COPII-coated vesicles and COPI-coated vesicles 
A) COPII-coated vesicles 
B) COPI-coated vesicles 
C) clathrin-coated vesicles 
D) cadmium-coated vesicles 
E) both COPII-coated vesicles and COPI-coated vesicles

What GTP-binding protein is associated with the formation of the COPI coat on COPI-coated vesicles?

What sugar is usually removed from the N-linked core oligosaccharide chains on proteins in the Golgi complex as opposed to the glucose residues trimmed off in the ER?

Which list below names the compartments into which chloroplast proteins must be imported?

Which protein(s)below is(are)recruited to the COPII coat by Sar1-GTP?

Why does glucocerebrosidase taken into macrophages by receptor-mediated endocytosis end up in lysosomes?

What recognizes ubiquitinated signaling receptors and sorts them into the membranes that give rise to the internal vesicles of the late endosomes?

What determines the function of a cell's smooth endoplasmic reticulum?

How is the orientation of membrane proteins in the membrane thought to be accomplished?

The outer and inner chloroplast membranes contain distinct translocation complexes named ________,respectively,that work together during protein import.

The three-legged assembly of protein chains that makes up a clathrin molecule and that can assemble into a network of polygons resembling a honeycomb is called a(n)_____.

What happens if misfolded proteins are generated in the ER at a faster rate than they can be exported to the cytoplasm?

TB 8.008 Elevated temperatures at which temperature-sensitive mutants do not work are called ________ temperatures.

In general,diseases that result from a deficiency of a single lysosomal enzyme are called ________.

What is thought to mediate the initial contacts between a transport vesicle and its target membrane,like a Golgi cisterna? Describe the two groups of tethering proteins.

The endomembrane system when homogenized is broken up into vesicles,which are heterogeneous but similar in size.These vesicles can be purified and,after purification,often retain their biological activity.They are collectively referred to as _________.

What do studies suggest governs the "decision" to destroy a defective protein that has been unable to fold correctly and has been in the ER for an extended period of time?

Which of the proteins below is(are)not made on the membrane-bound ribosomes of the RER?

Which coated vesicles move materials in a retrograde direction from the ERGIC and Golgi stack backwards toward the ER?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Exam 8: Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

What GTP-binding protein is associated with the formation of the COPI coat on COPI-coated vesicles?

What sugar is usually removed from the N-linked core oligosaccharide chains on proteins in the Golgi complex as opposed to the glucose residues trimmed off in the ER?

Which list below names the compartments into which chloroplast proteins must be imported?

Which protein(s)below is(are)recruited to the COPII coat by Sar1-GTP?

Why does glucocerebrosidase taken into macrophages by receptor-mediated endocytosis end up in lysosomes?

What recognizes ubiquitinated signaling receptors and sorts them into the membranes that give rise to the internal vesicles of the late endosomes?

What determines the function of a cell's smooth endoplasmic reticulum?

How is the orientation of membrane proteins in the membrane thought to be accomplished?

The outer and inner chloroplast membranes contain distinct translocation complexes named ________,respectively,that work together during protein import.

The three-legged assembly of protein chains that makes up a clathrin molecule and that can assemble into a network of polygons resembling a honeycomb is called a(n)_____.

What happens if misfolded proteins are generated in the ER at a faster rate than they can be exported to the cytoplasm?

TB 8.008 Elevated temperatures at which temperature-sensitive mutants do not work are called ________ temperatures.

In general,diseases that result from a deficiency of a single lysosomal enzyme are called ________.

What is thought to mediate the initial contacts between a transport vesicle and its target membrane,like a Golgi cisterna? Describe the two groups of tethering proteins.

The endomembrane system when homogenized is broken up into vesicles,which are heterogeneous but similar in size.These vesicles can be purified and,after purification,often retain their biological activity.They are collectively referred to as _________.

What do studies suggest governs the "decision" to destroy a defective protein that has been unable to fold correctly and has been in the ER for an extended period of time?

Which of the proteins below is(are)not made on the membrane-bound ribosomes of the RER?

Which coated vesicles move materials in a retrograde direction from the ERGIC and Golgi stack backwards toward the ER?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters