Exam 8: Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

What recently developed technique allows scientists to follow with their own eyes the dynamic movements of specific proteins as they occur within the living cell?

What circumstantial evidence supports the proposed role of the Rabs in recruiting cytosolic tethering proteins to specific membrane surfaces?

What effect does the binding of the SRP to the growing polypeptide chain and the ribosome have on protein synthesis?

What is thought to shield lysosomal membranes against attack by their enclosed enzymes?

Phospholipids are made by integral ER membrane enzymes whose active sites face the cytosol and they are inserted into the outer (cytoplasmic)leaflet of the ER membrane.How then do lipids destined for the luminal leaflet of the ER membrane get there?

You homogenize a liver cell and isolate from it vesicles derived from the endoplasmic reticulum.When their biochemistry is analyzed,they are found to contain oxygenases.From what type of ER are they derived?

What is it about lysosomes that initially deactivates most ingested bacteria?

Which of the following organelles imports proteins through one or more outer boundary membranes?

What types of molecules below can a cell internalize by receptor-mediated endocytosis?

When electron micrographs were first taken of the cell interior,what kinds of membranous structures were seen?

Which procedure below would lead to the visualization of the dynamic movements of specific proteins as they move through a single living cell? The proteins can be seen through the microscope eyepiece and the cells do not have to be killed for the protein to be detected.

Most proteins destined for the chloroplast are synthesized with a removable ________ called the ______.

What leads to the degradation of the contents of late endosomes by lysosomal enzymes?

How are integral membrane proteins thought to enter the lipid bilayer?

What happens to yeast cells that cannot transport proteins into the ER lumen cotranslationally?

What happened to COPI-coated vesicles within the cell when the cell was treated with GTP analogues that could not be hydrolyzed?

What appears to be the purpose of molecular chaperones like BiP?

Synaptic vesicle fusion to the presynaptic membrane in a neuron is regulated by what calcium-binding protein found in the membrane of the synaptic vesicle?

I-cell disease is typified by __________.

When cells are homogenized,the cytomembrane system is broken into fragments,the ends of which can fuse to form small membranous spheres called ________.