Question 1

A mutation that changes a GC base pair to AT is a(n):

Accepted Answer

A) transition. 
B) transversion. 
C) induced mutation. 
D) missense mutation. 
E) synonymous mutation. 
A) transition. 
B) transversion. 
C) induced mutation. 
D) missense mutation. 
E) synonymous mutation.

Question 2

To determine whether human exposure to radiation results in an increase in recessive mutations in the germ line, scientists can examine the sex ratio of children born to parents exposed to higher than normal radiation levels.Explain how and why the sex ratio might be affected by radiation exposure.

Accepted Answer

The important mutations here are those i

Question 3

Explain how an individual with a suppressor mutation can be a double mutant but express a near normal phenotype.

Accepted Answer

A suppressor mutation is a mutation that

Question 4

How do insertion sequences and composite transposons differ?

Accepted Answer

(1)Insertion sequences contain genes req

Question 5

In a eukaryotic cell, two different transposable elements, each containing an intron, excise and insert in different locations within the genome.After transposition, the transposable elements are sequenced at their new sites.Explain the following sequencing results.
a.Neither of the translocated transposable elements contains any intron sequences.
b.One of the transposable elements contains the intron, but the other transposable elements do not.

Accepted Answer

a.The transposition process itself must

Question 6

How will the result of strand slippage on the newly synthesized strand differ from the result of strand slippage on the template strand?

Accepted Answer

Slippage on the newly synthesi

Question 7

What are the differences between neutral mutations and silent mutations?

Accepted Answer

Neutral mutations are changes in DNA seq

Question 8

Which of the following mutagens is MOST likely to cause a frameshift mutation?

Accepted Answer

A) Base analog 
B) Alkylating agent 
C) Intercalating agent 
D) Ionizing radiation 
E) UV light 
A) Base analog 
B) Alkylating agent 
C) Intercalating agent 
D) Ionizing radiation 
E) UV light

Question 9

Reversions, or reverse mutations (i.e., mutations that restore the wild-type phenotype initially lost by an earlier mutation), can be either of two types: back mutations or suppressor mutations.How you could distinguish between these two different types of reversions?

Accepted Answer

If the reversion is a back mut

Question 10

Which of the following is the MOST common transposable element in humans?

Accepted Answer

A) copia 
B) Alu 
C) Ac 
D) Ty 
E) P 
A) copia 
B) Alu 
C) Ac 
D) Ty 
E) P

Question 11

The type of mutation that reverses the effects of a frameshift mutation without changing the frameshift and occurs with the same gene as the frameshift is called a(n)_____ mutation.

Accepted Answer

A) intergenic suppressor 
B) nonsense 
C) missense 
D) intragenic suppressor 
E) silent 
A) intergenic suppressor 
B) nonsense 
C) missense 
D) intragenic suppressor 
E) silent

Question 12

A nonreplicative transposon does not leave a copy at its original site upon transposition.In contrast, a replicative transposon:

Accepted Answer

A) leaves two copies at the original site. 
B) creates an original copy and a new one in the genome. 
C) leaves two copies at the new insertion site. 
D) replicates itself at the original site but does not create a new copy in the genome. 
E) leaves a deletion at the original site. 
A) leaves two copies at the original site. 
B) creates an original copy and a new one in the genome. 
C) leaves two copies at the new insertion site. 
D) replicates itself at the original site but does not create a new copy in the genome. 
E) leaves a deletion at the original site.

Question 13

Some mutations cause new alleles that are helpful in a population, whereas some mutations can be deleterious, such as those that cause:

Accepted Answer

A) altered gene expression. 
B) new protein forms. 
C) gene duplications. 
D) genetic disease. 
E) new phenotypes. 
A) altered gene expression. 
B) new protein forms. 
C) gene duplications. 
D) genetic disease. 
E) new phenotypes.

Question 14

Which of the following kinds of mutations is MOST likely to be a null loss-of-function?

Accepted Answer

A) Transition 
B) Transversion 
C) Frameshift 
D) Missense 
E) Induced 
A) Transition 
B) Transversion 
C) Frameshift 
D) Missense 
E) Induced

Question 15

Why don't transposable elements that move through replicative transposition eventually take over the genome completely?

Accepted Answer

Organisms have evolved mechanisms to reg

Question 16

Transposition can involve exchange of DNA sequences and recombination, which often leads to DNA:

Accepted Answer

A) acetylation. 
B) rearrangements. 
C) condensation. 
D) repair. 
E) replication. 
A) acetylation. 
B) rearrangements. 
C) condensation. 
D) repair. 
E) replication.

Question 17

Explain how UV light induces mutations in E.coli.

Accepted Answer

DNA bases absorb UV light, resulting in

Question 18

Assume that a base-pair substitution mutation converts a DNA triplet (AAT)to another DNA triplet (AAA).A second mutation now changes the AAA triplet to the GAA triplet.(UUA and CUU code for leucine, and UUU codes for phenylalanine.)This second mutation is an example of a(n):

Accepted Answer

A) transversion. 
B) intragenic suppressor. 
C) loss-of-function mutation. 
D) intergenic suppressor. 
E) frameshift. 
A) transversion. 
B) intragenic suppressor. 
C) loss-of-function mutation. 
D) intergenic suppressor. 
E) frameshift.

Question 19

Which of the following describes the possible parasitic nature of transposable elements?

Accepted Answer

A) Transposable elements can increase in number within genomes without providing an advantage to the host. 
B) Transposable elements are collected within their genomes by host organisms so that the host will benefit, but not the transposable elements. 
C) Transposable elements will provide an evolutionary advantage to host organisms by transposing as often as possible. 
D) Transposable elements will enhance their expression of transposase so that the hosts can evolve more quickly. 
E) Transposable elements will add methyl groups to their own DNA to reduce their own rate of transposition. 
A) Transposable elements can increase in number within genomes without providing an advantage to the host. 
B) Transposable elements are collected within their genomes by host organisms so that the host will benefit, but not the transposable elements. 
C) Transposable elements will provide an evolutionary advantage to host organisms by transposing as often as possible. 
D) Transposable elements will enhance their expression of transposase so that the hosts can evolve more quickly. 
E) Transposable elements will add methyl groups to their own DNA to reduce their own rate of transposition.

Question 20

Which of the following pairs of DNA-repair systems will repair pyrimidine dimers in E.coli?

Accepted Answer

A) Mismatch repair and base-excision repair 
B) Photoreactivation and mismatch repair 
C) Nucleotide-excision repair and base-excision repair 
D) SOS repair 
E) Nonhomologous end joining and nucleotide-excision repair 
A) Mismatch repair and base-excision repair 
B) Photoreactivation and mismatch repair 
C) Nucleotide-excision repair and base-excision repair 
D) SOS repair 
E) Nonhomologous end joining and nucleotide-excision repair

A mutation that changes a GC base pair to AT is a(n):

To determine whether human exposure to radiation results in an increase in recessive mutations in the germ line, scientists can examine the sex ratio of children born to parents exposed to higher than normal radiation levels.Explain how and why the sex ratio might be affected by radiation exposure.

Explain how an individual with a suppressor mutation can be a double mutant but express a near normal phenotype.

How do insertion sequences and composite transposons differ?

How will the result of strand slippage on the newly synthesized strand differ from the result of strand slippage on the template strand?

What are the differences between neutral mutations and silent mutations?

Which of the following mutagens is MOST likely to cause a frameshift mutation?

Reversions, or reverse mutations (i.e., mutations that restore the wild-type phenotype initially lost by an earlier mutation), can be either of two types: back mutations or suppressor mutations.How you could distinguish between these two different types of reversions?

Which of the following is the MOST common transposable element in humans?

The type of mutation that reverses the effects of a frameshift mutation without changing the frameshift and occurs with the same gene as the frameshift is called a(n)_____ mutation.

A nonreplicative transposon does not leave a copy at its original site upon transposition.In contrast, a replicative transposon:

Some mutations cause new alleles that are helpful in a population, whereas some mutations can be deleterious, such as those that cause:

Which of the following kinds of mutations is MOST likely to be a null loss-of-function?

Why don't transposable elements that move through replicative transposition eventually take over the genome completely?

Transposition can involve exchange of DNA sequences and recombination, which often leads to DNA:

Explain how UV light induces mutations in E.coli.

Assume that a base-pair substitution mutation converts a DNA triplet (AAT)to another DNA triplet (AAA).A second mutation now changes the AAA triplet to the GAA triplet.(UUA and CUU code for leucine, and UUU codes for phenylalanine.)This second mutation is an example of a(n):

Which of the following describes the possible parasitic nature of transposable elements?

Which of the following pairs of DNA-repair systems will repair pyrimidine dimers in E.coli?

Introduction to Genetics

Chromosomes and Cellular Reproduction

Basic Principles of Heredity

Sex Determination and Sex-Linked Characteristics

Linkage, Recombination, and Eukaryotic Gene Mapping

Chromosome Variation

Bacterial and Viral Genetic Systems

DNA- the Chemical Nature of the Gene

DNA Replication and Recombination

From DNA to Proteins- Transcription and Rna Processing

From DNA to Protein- Translation

Control of Gene Expression

Molecular Genetic Analysis and Biotechnology

Genomics and Proteomics

Cancer Genetics

Quantitative Genetics

Population and Evolutionary Genetics

Filters

Exam 13: Gene Mutations, Transposable Elements, and Dna Repair

A mutation that changes a GC base pair to AT is a(n):

To determine whether human exposure to radiation results in an increase in recessive mutations in the germ line, scientists can examine the sex ratio of children born to parents exposed to higher than normal radiation levels.Explain how and why the sex ratio might be affected by radiation exposure.

Explain how an individual with a suppressor mutation can be a double mutant but express a near normal phenotype.

How do insertion sequences and composite transposons differ?

How will the result of strand slippage on the newly synthesized strand differ from the result of strand slippage on the template strand?

What are the differences between neutral mutations and silent mutations?

Which of the following mutagens is MOST likely to cause a frameshift mutation?

Reversions, or reverse mutations (i.e., mutations that restore the wild-type phenotype initially lost by an earlier mutation), can be either of two types: back mutations or suppressor mutations.How you could distinguish between these two different types of reversions?

Which of the following is the MOST common transposable element in humans?

The type of mutation that reverses the effects of a frameshift mutation without changing the frameshift and occurs with the same gene as the frameshift is called a(n)_____ mutation.

A nonreplicative transposon does not leave a copy at its original site upon transposition.In contrast, a replicative transposon:

Some mutations cause new alleles that are helpful in a population, whereas some mutations can be deleterious, such as those that cause:

Which of the following kinds of mutations is MOST likely to be a null loss-of-function?

Why don't transposable elements that move through replicative transposition eventually take over the genome completely?

Transposition can involve exchange of DNA sequences and recombination, which often leads to DNA:

Explain how UV light induces mutations in E.coli.

Assume that a base-pair substitution mutation converts a DNA triplet (AAT)to another DNA triplet (AAA).A second mutation now changes the AAA triplet to the GAA triplet.(UUA and CUU code for leucine, and UUU codes for phenylalanine.)This second mutation is an example of a(n):

Which of the following describes the possible parasitic nature of transposable elements?

Which of the following pairs of DNA-repair systems will repair pyrimidine dimers in E.coli?

Introduction to Genetics

Chromosomes and Cellular Reproduction

Basic Principles of Heredity

Sex Determination and Sex-Linked Characteristics

Linkage, Recombination, and Eukaryotic Gene Mapping

Chromosome Variation

Bacterial and Viral Genetic Systems

DNA- the Chemical Nature of the Gene

DNA Replication and Recombination

From DNA to Proteins- Transcription and Rna Processing

From DNA to Protein- Translation

Control of Gene Expression

Molecular Genetic Analysis and Biotechnology

Genomics and Proteomics

Cancer Genetics

Quantitative Genetics

Population and Evolutionary Genetics

Filters