Question 1

Susie has an acute infection-strep throat-and her friend Zoe has a chronic illness, systemic lupus erythematosus.

Accepted Answer

A) Susie probably has an elevated CH 50 while Zoe probably has a decreased CH50. 
B) Susie probably has a decreased CH 50 while Zoe probably has an increased CH50. 
C) Both Susie and Zoe probably have an elevated CH 50. 
D) Both Susie and Zoe probably have a decreased CH 50. 
A) Susie probably has an elevated CH 50 while Zoe probably has a decreased CH50. 
B) Susie probably has a decreased CH 50 while Zoe probably has an increased CH50. 
C) Both Susie and Zoe probably have an elevated CH 50. 
D) Both Susie and Zoe probably have a decreased CH 50.

Question 2

The AH50 differs from the CH50 because the AH50

Accepted Answer

A) measures the alternative pathway and the CH50 measures the classical pathway 
B) measures the classical pathway and the CH50 measures the alternative pathway 
C) uses rabbit red blood cells and the CH50 uses sheep red blood cells with antibody 
D) measures the alternative pathway and the CH50 measures the classical pathway and uses rabbit red blood cells and the CH50 uses sheep red blood cells with antibody 
E) measures the classical pathway and the CH50 measures the alternative pathway and uses rabbit red blood cells and the CH50 uses sheep red blood cells with antibody 
A) measures the alternative pathway and the CH50 measures the classical pathway 
B) measures the classical pathway and the CH50 measures the alternative pathway 
C) uses rabbit red blood cells and the CH50 uses sheep red blood cells with antibody 
D) measures the alternative pathway and the CH50 measures the classical pathway and uses rabbit red blood cells and the CH50 uses sheep red blood cells with antibody 
E) measures the classical pathway and the CH50 measures the alternative pathway and uses rabbit red blood cells and the CH50 uses sheep red blood cells with antibody

Question 3

What molecule is needed for C1q,r and s to stay together?

Accepted Answer

A) Mg++ 
B) Ca++ and Mg++ 
C) Ca++ 
D) none of the above 
A) Mg++ 
B) Ca++ and Mg++ 
C) Ca++ 
D) none of the above

Question 4

Complement proteins are synthesized by

Accepted Answer

A) the liver 
B) monocytes 
C) macrophages 
D) epithelial cells 
E) All of the above 
A) the liver 
B) monocytes 
C) macrophages 
D) epithelial cells 
E) All of the above

Question 5

Which pathway(s) can act as a powerful amplifier of the other pathways?

Accepted Answer

A) the classical pathway 
B) the alternative pathway 
C) the lectin pathway 
D) all of the pathways can amplify each other 
A) the classical pathway 
B) the alternative pathway 
C) the lectin pathway 
D) all of the pathways can amplify each other

Question 6

Anaphylatoxins include

Accepted Answer

A) C5a 
B) C4a 
C) C3a 
D) C5a and C4a 
E) all of the above 
A) C5a 
B) C4a 
C) C3a 
D) C5a and C4a 
E) all of the above

Question 7

The difference in the three pathways is the way the C3 convertase is formed

Accepted Answer

A) in the classical pathway, the C3 convertase is C1C2; in the alternative pathway, it is C3wBb; and in the MBL pathway, the C3 convertase is C2aC4b 
B) in the classical pathway, the C3 convertase is C2aC4b' in the alternative pathway, it is C3wBb; and in the MBL pathway, the C3 convertase is C2aC4b 
C) in the classical pathway, the C3 convertase is C1C2; in the alternative pathway, it is C3wBb; and in the MBL pathway, the C3 convertase is MBL-MASP-2 
D) in the classical pathway, the C3 convertase is C2aC4b; in the alternative pathway, it is PDBb; and in the MBL pathway, the C3 convertase is C2aC4b 
A) in the classical pathway, the C3 convertase is C1C2; in the alternative pathway, it is C3wBb; and in the MBL pathway, the C3 convertase is C2aC4b 
B) in the classical pathway, the C3 convertase is C2aC4b' in the alternative pathway, it is C3wBb; and in the MBL pathway, the C3 convertase is C2aC4b 
C) in the classical pathway, the C3 convertase is C1C2; in the alternative pathway, it is C3wBb; and in the MBL pathway, the C3 convertase is MBL-MASP-2 
D) in the classical pathway, the C3 convertase is C2aC4b; in the alternative pathway, it is PDBb; and in the MBL pathway, the C3 convertase is C2aC4b

Question 8

Amplification steps in the complement pathways occur

Accepted Answer

A) in the classical pathway with C1 cleaving multiple molecules of C4 and multiple C2 for every C1 and C4; in the alternative pathway with the C3b of other pathways becoming C3 convertase; and then the C3b becoming part of a C5 convertase 
B) in all pathways with all the C3 convertases making multiple C3a +C3b 
C) with C9 polymerization 
D) all of the above 
E) A and B only 
A) in the classical pathway with C1 cleaving multiple molecules of C4 and multiple C2 for every C1 and C4; in the alternative pathway with the C3b of other pathways becoming C3 convertase; and then the C3b becoming part of a C5 convertase 
B) in all pathways with all the C3 convertases making multiple C3a +C3b 
C) with C9 polymerization 
D) all of the above 
E) A and B only

Question 9

Complement

Accepted Answer

A) aids in immune complex clearance 
B) interacts with the coagulation pathway 
C) can be involved in immune memory enhancement 
D) all of the above 
E) A and C only 
A) aids in immune complex clearance 
B) interacts with the coagulation pathway 
C) can be involved in immune memory enhancement 
D) all of the above 
E) A and C only

Question 10

Collectin is

Accepted Answer

A) another name for the mannose-binding lectin 
B) a name for the collective processes involved in all complement pathways 
C) a receptor for C3b 
D) a receptor for C1q 
A) another name for the mannose-binding lectin 
B) a name for the collective processes involved in all complement pathways 
C) a receptor for C3b 
D) a receptor for C1q

Question 11

Complement

Accepted Answer

A) causes lysis of gram-positive cells and has no effect on gram-negative cells 
B) causes lysis of gram-negative cells and has no effect on gram-positive cells 
C) causes lysis of gram-positive cells and increases the amount of phagocytosis of gram-negative cells 
D) causes lysis of gram-negative cells and increases the amount of phagocytosis of gram-positive cells 
A) causes lysis of gram-positive cells and has no effect on gram-negative cells 
B) causes lysis of gram-negative cells and has no effect on gram-positive cells 
C) causes lysis of gram-positive cells and increases the amount of phagocytosis of gram-negative cells 
D) causes lysis of gram-negative cells and increases the amount of phagocytosis of gram-positive cells

Question 12

Sometimes a microorganism can directly activate complement through

Accepted Answer

A) the alternative pathway only 
B) the lectin pathway only 
C) the alternative and the lectin pathway 
D) usually the alternative and the lectin pathways, but with some microorganisms, also the classical pathway 
A) the alternative pathway only 
B) the lectin pathway only 
C) the alternative and the lectin pathway 
D) usually the alternative and the lectin pathways, but with some microorganisms, also the classical pathway

Question 13

MBL binds

Accepted Answer

A) mannose and MASP-2 become associated and cleave C2 and C4 
B) mannose and MASP-1 become associated and cleave C4 
C) ficolin and MASP-2 become associated and cleave C2 and C4 
D) membranes and MASP-1 become associated and cleave C2 and C4 
A) mannose and MASP-2 become associated and cleave C2 and C4 
B) mannose and MASP-1 become associated and cleave C4 
C) ficolin and MASP-2 become associated and cleave C2 and C4 
D) membranes and MASP-1 become associated and cleave C2 and C4

Question 14

Which of the following is an active C3 convertase?

Accepted Answer

A) C4bC2a 
B) C3bC5b 
C) C4bC2a. 
D) BbDd 
A) C4bC2a 
B) C3bC5b 
C) C4bC2a. 
D) BbDd

Susie has an acute infection-strep throat-and her friend Zoe has a chronic illness, systemic lupus erythematosus.

The AH50 differs from the CH50 because the AH50

What molecule is needed for C1q,r and s to stay together?

Complement proteins are synthesized by

Which pathway(s) can act as a powerful amplifier of the other pathways?

Anaphylatoxins include

The difference in the three pathways is the way the C3 convertase is formed

Amplification steps in the complement pathways occur

Complement

Collectin is

Complement

Sometimes a microorganism can directly activate complement through

MBL binds

Which of the following is an active C3 convertase?

Introduction to Immunology

Antibody

Antigens-Epitopes and Immunogenicity

Cellular Immunity

Agglutination and Precipitation Reactions: the Unlabeled Immunoassays

Labeled Immunoassays

Serology Laboratory Math

Hypersensitivity Reactions

Autoimmunitysystemic

Autoimmunityorgan or Tissue Specific

Tumor Immunology

Hematopoeitc Malignancies

Immunology of Transplantation

Primary Immunodeficiency Diseases

Acquired Immunodeficiency Including Hiv and Aids

Hepatitis

Serology and Viruses Herpesviridae Family and Other Serologically

Bacterial Serology

Fungal Serology Parasitic Serology

Forensic Serology

Safety

Molecular Biology

Filters

Exam 5: Complement Pathways

Susie has an acute infection-strep throat-and her friend Zoe has a chronic illness, systemic lupus erythematosus.

The AH50 differs from the CH50 because the AH50

What molecule is needed for C1q,r and s to stay together?

Complement proteins are synthesized by

Which pathway(s) can act as a powerful amplifier of the other pathways?

Anaphylatoxins include

The difference in the three pathways is the way the C3 convertase is formed

Amplification steps in the complement pathways occur

Complement

Collectin is

Complement

Sometimes a microorganism can directly activate complement through

MBL binds

Which of the following is an active C3 convertase?

Introduction to Immunology

Antibody

Antigens-Epitopes and Immunogenicity

Cellular Immunity

Agglutination and Precipitation Reactions: the Unlabeled Immunoassays

Labeled Immunoassays

Serology Laboratory Math

Hypersensitivity Reactions

Autoimmunitysystemic

Autoimmunityorgan or Tissue Specific

Tumor Immunology

Hematopoeitc Malignancies

Immunology of Transplantation

Primary Immunodeficiency Diseases

Acquired Immunodeficiency Including Hiv and Aids

Hepatitis

Serology and Viruses Herpesviridae Family and Other Serologically

Bacterial Serology

Fungal Serology Parasitic Serology

Forensic Serology

Safety

Molecular Biology

Filters