Exam 32: The Control of Gene Expression in Eukaryotes

Which of the following are ways in which eukaryotic gene expression is more complex than prokaryotic gene expression?

DNA regions that serve as binding sites for transcription factors which can act at a distance to perturb the local chromatin structure are called _________________.

One of the classes of eukaryotic DNA-binding units is called bZip proteins because it has long α-helices stabilized by the amino acid __________________.

The repeating unit formed by the DNA wrapping around the histone core is called a(n)_________________.

A zinc finger domain is stabilized by a bound zinc ion through interactions with two __________ and two ______________ residues.

Briefly describe the path of a steroid hormone in gene regulation.

Describe the mechanism by which a steroid hormone receptor antagonist can function as a drug.

In eukaryotes, DNA-binding proteins bind to DNA by which of the following DNA-binding structures?

Structural components of the nucleosome include

What eukaryotic DNA binding structure is similar to the prokaryotic helix-turn-helix?

What are significant features in the development of induced pluripotent stem cells?

What are binding sites, present on DNA, that bind regulatory proteins, resulting in an increased level of transcription for a gene that is distant from the binding site?

Histone binding and wrapping of DNA reduces the DNA length by

When a steroid hormone receptor binds its ligand, it induces a conformational change in the ligand-binding domain which allows the binding of a(n) _______________.

Molecules that bind to a receptor and trigger signaling pathways are called

A key reaction in gene repression is the deacetylation of these amino acids in histones.

How does a coactivator function in gene expression?

Posttranscriptional eukaryotic gene expression can be controlled by

What are proteins that act in a coordinated manner with hormone receptors to mediate gene expression?

Gene regulation by microRNAs involves