Question 1

What has been learned about ATP binding and hydrolysis in the helicase mechanism through the use of the non-hydrolyzable ATP analog, AMP-PNP?

Accepted Answer

Of the six helicase subunits, only four

Question 2

Huntington's disease is caused by

Accepted Answer

A)  pyrimidine dimers. 
B)  trinucleotide expansion. 
C)  improper DNA methylation. 
D)  suppressor mutants. 
E)  None of the answers is correct. 
A)  pyrimidine dimers. 
B)  trinucleotide expansion. 
C)  improper DNA methylation. 
D)  suppressor mutants. 
E)  None of the answers is correct.

Question 3

The mechanism by which type I topoisomerase relaxes DNA includes which of the following?

Accepted Answer

A)  The OH of Tyr 723 attacks a phosphate group on one DNA strand. 
B)  When the backbone of one strand is cleaved, the DNA rotates. 
C)  ATP binds, leading to a conformation change. 
D)  All the answers are correct. 
E)  The OH of Tyr 723 attacks a phosphate group on one DNA strand, and when the backbone of one strand is cleaved, the DNA rotates. 
A)  The OH of Tyr 723 attacks a phosphate group on one DNA strand. 
B)  When the backbone of one strand is cleaved, the DNA rotates. 
C)  ATP binds, leading to a conformation change. 
D)  All the answers are correct. 
E)  The OH of Tyr 723 attacks a phosphate group on one DNA strand, and when the backbone of one strand is cleaved, the DNA rotates.

Question 4

What type of topoisomerase does NOT require ATP?

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  All topoisomerases require ATP. 
A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  All topoisomerases require ATP.

Question 5

What does the phrase "recombination of genetic material" refer to?

Accepted Answer

Two daughter molecules are for

Question 6

How is the processivity of DNA polymerase III accomplished?

Accepted Answer

The structure of the enzyme complex allo

Question 7

________________ are intermediates in recombination pathways composed of four polynucleotide chains in a cross-like structure.

Accepted Answer

The answer of ________________ are intermediates in recombination pathways composed...

Question 8

What role does the protein RecA play in recombination?

Accepted Answer

RecA promotes the formation of

Exam 28: DNA Replication, Repair, and Recombination

What has been learned about ATP binding and hydrolysis in the helicase mechanism through the use of the non-hydrolyzable ATP analog, AMP-PNP?

Huntington's disease is caused by

The mechanism by which type I topoisomerase relaxes DNA includes which of the following?

What type of topoisomerase does NOT require ATP?

What does the phrase "recombination of genetic material" refer to?

How is the processivity of DNA polymerase III accomplished?

________________ are intermediates in recombination pathways composed of four polynucleotide chains in a cross-like structure.

What role does the protein RecA play in recombination?

Biochemistry: an Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Oxidative Phosphorylation

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

Rna Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters