Question 1

The cytosolic side, or β subunit, of the insulin receptor is a ________________ kinase.

Accepted Answer

The answer of The cytosolic side, or β subunit, of...

Question 2

What enzyme becomes active when bound to Ca2+ and diacylglycerol?

Accepted Answer

A)  calmodulin 
B)  protein kinase A 
C)  protein kinase C 
D)  phospholipase C 
E)  adenylate cyclase 
A)  calmodulin 
B)  protein kinase A 
C)  protein kinase C 
D)  phospholipase C 
E)  adenylate cyclase

Question 3

Most signal molecules

Accepted Answer

A)  easily diffuse through the membrane and bind to a receptor in the cytoplasm. 
B)  bind to membrane receptors and transmit information across a membrane without traversing the membrane. 
C)  carry out functions in the nucleus after binding to a receptor in the cell membrane. 
D)  easily diffuse through the membrane and bind to a receptor in the nucleus. 
E)  None of the answers is correct. 
A)  easily diffuse through the membrane and bind to a receptor in the cytoplasm. 
B)  bind to membrane receptors and transmit information across a membrane without traversing the membrane. 
C)  carry out functions in the nucleus after binding to a receptor in the cell membrane. 
D)  easily diffuse through the membrane and bind to a receptor in the nucleus. 
E)  None of the answers is correct.

Question 4

Which of the following is a common example of a mechanism by which a signaling process might be terminated?

Accepted Answer

A)  change in temperature 
B)  aggregation of all protein subunits 
C)  protein dephosphorylation by phosphatases 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  change in temperature 
B)  aggregation of all protein subunits 
C)  protein dephosphorylation by phosphatases 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 5

What eukaryotic protein serves as an intracellular Ca2+ sensor by binding to four calcium ions?

Accepted Answer

A)  calmodulin 
B)  phospholipase C 
C)  protein kinase C 
D)  vitamin D-dependent calcium binding protein 
E)  calcitonin 
A)  calmodulin 
B)  phospholipase C 
C)  protein kinase C 
D)  vitamin D-dependent calcium binding protein 
E)  calcitonin

Question 6

Common elements that occur in many signal transduction pathways include which of the following?

Accepted Answer

A)  Specialized domains mediate specific interactions in the pathway. 
B)  Second messengers may participate. 
C)  Cell division is usually the result. 
D)  A and B 
E)  All of the answers are correct. 
A)  Specialized domains mediate specific interactions in the pathway. 
B)  Second messengers may participate. 
C)  Cell division is usually the result. 
D)  A and B 
E)  All of the answers are correct.

Question 7

Examples of second messengers include

Accepted Answer

A)  cAMP. 
B)  calcium. 
C)  inositol 1,4,5-trisphosphate. 
D)  cGMP. 
E)  All of the answers are correct. 
A)  cAMP. 
B)  calcium. 
C)  inositol 1,4,5-trisphosphate. 
D)  cGMP. 
E)  All of the answers are correct.

Question 8

What is meant by an EF hand? Draw or describe the structure.

Accepted Answer

The EF hand is a protein that binds calc

Question 9

______________ may be effective anti-cancer drugs.

Accepted Answer

A)  Monoclonal antibodies against offending receptors 
B)  EGF mimics 
C)  Protein kinase inhibitors 
D)  All of the answers are correct. 
E)  Both monoclonal antibodies against offending receptors and protein kinase inhibitors 
A)  Monoclonal antibodies against offending receptors 
B)  EGF mimics 
C)  Protein kinase inhibitors 
D)  All of the answers are correct. 
E)  Both monoclonal antibodies against offending receptors and protein kinase inhibitors

Exam 14: Signal-Transduction Pathways

The cytosolic side, or β subunit, of the insulin receptor is a ________________ kinase.

What enzyme becomes active when bound to Ca2+ and diacylglycerol?

Most signal molecules

Which of the following is a common example of a mechanism by which a signaling process might be terminated?

What eukaryotic protein serves as an intracellular Ca2+ sensor by binding to four calcium ions?

Common elements that occur in many signal transduction pathways include which of the following?

Examples of second messengers include

What is meant by an EF hand? Draw or describe the structure.

______________ may be effective anti-cancer drugs.

Biochemistry: an Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Oxidative Phosphorylation

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, Repair, and Recombination

Rna Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters

What enzyme becomes active when bound to Ca²⁺ and diacylglycerol?

What eukaryotic protein serves as an intracellular Ca²⁺ sensor by binding to four calcium ions?