Question 1

What are the three aromatic amino acids?

Accepted Answer

phenylalan

Question 2

The ________________________ β-sheet structure occurs when the two strands are oriented in the same directions (N →C).

Accepted Answer

The answer of The ________________________ β-sheet structure occurs when the...

Question 3

A term that describes a molecule that contains both positive and negative charges but overall has a neutral charge is _____.

Accepted Answer

A)  enantiomer 
B)  amino acid 
C)  racemate 
D)  zwitterion 
E)  amphipath 
A)  enantiomer 
B)  amino acid 
C)  racemate 
D)  zwitterion 
E)  amphipath

Question 4

Formation of a peptide bond produces _____ as a byproduct.

Accepted Answer

A)  ammonia 
B)  carbon dioxide 
C)  water 
D)  H+ 
E)  OH- 
A)  ammonia 
B)  carbon dioxide 
C)  water 
D)  H+ 
E)  OH-

Question 5

What level of protein structure is composed of $\alpha$ helices, $\beta$ sheets, and turns?

Accepted Answer

A)  primary 
B)  secondary 
C)  tertiary 
D)  quaternary 
E)  both secondary and tertiary 
A)  primary 
B)  secondary 
C)  tertiary 
D)  quaternary 
E)  both secondary and tertiary

Question 6

The overall three-dimensional structure of a single polypeptide is referred to as _____.

Accepted Answer

A)  primary structure 
B)  secondary structure 
C)  tertiary structure 
D)  quaternary structure 
E)  both secondary structure and tertiary structure 
A)  primary structure 
B)  secondary structure 
C)  tertiary structure 
D)  quaternary structure 
E)  both secondary structure and tertiary structure

Question 7

Why is the peptide bond planar?

Accepted Answer

A)  Bulky side chains prevent free rotation around the bond. 
B)  It contains partial double-bond character, preventing rotation. 
C)  Hydrogen bonding between the NH and C=O groups limits movement. 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  Bulky side chains prevent free rotation around the bond. 
B)  It contains partial double-bond character, preventing rotation. 
C)  Hydrogen bonding between the NH and C=O groups limits movement. 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 8

______________________ is the major fibrous protein present in skin, bone, tendon, cartilage, and teeth.

Accepted Answer

The answer of ______________________ is the major fibrous protein present...

Question 9

Disulfide bonds in proteins can be reduced to free sulfhydryl groups by reagents such as _____________________.

Accepted Answer

The answer of Disulfide bonds in proteins can be reduced...

Question 10

What structure(s) did Pauling and Corey predict in 1951?

Accepted Answer

A)  α helix 
B)  β sheet 
C)  β turns 
D)  Pauling and Corey predicted all three of these structures. 
E)  α helix and β sheet 
A)  α helix 
B)  β sheet 
C)  β turns 
D)  Pauling and Corey predicted all three of these structures. 
E)  α helix and β sheet

Question 11

Which of the following amino acid residues would most likely be buried in the interior of a water-soluble, globular protein?

Accepted Answer

A)  Asp 
B)  Ser 
C)  Phe 
D)  Lys 
E)  Gln 
A)  Asp 
B)  Ser 
C)  Phe 
D)  Lys 
E)  Gln

Question 12

The term "quaternary" with respect to protein structure means

Accepted Answer

A)  a repeating structure stabilized by intrachain hydrogen bonds. 
B)  the ability to form all four kinds of noncovalent bonds. 
C)  a multisubunit structure. 
D)  a linear sequence of four amino acids. 
E)  None of the answers is correct. 
A)  a repeating structure stabilized by intrachain hydrogen bonds. 
B)  the ability to form all four kinds of noncovalent bonds. 
C)  a multisubunit structure. 
D)  a linear sequence of four amino acids. 
E)  None of the answers is correct.

Question 13

What is the advantage of having certain areas of partially correct folded regions?

Accepted Answer

If some regions interact prefe

Question 14

What type of plot allows one to investigate the likely phi and psi angles of the peptide backbone?

Accepted Answer

A)  Hill 
B)  Lineweaver-Burk 
C)  Hanes-Woolf 
D)  Ramachandran 
E)  Michaelis-Menten 
A)  Hill 
B)  Lineweaver-Burk 
C)  Hanes-Woolf 
D)  Ramachandran 
E)  Michaelis-Menten

Question 15

Where are Ω and β turns and loops often found?

Accepted Answer

A)  in a hydrophobic pocket 
B)  on the interior cleft 
C)  at the protein interface with ligand 
D)  on the surface of proteins 
E)  None of the answers is correct. 
A)  in a hydrophobic pocket 
B)  on the interior cleft 
C)  at the protein interface with ligand 
D)  on the surface of proteins 
E)  None of the answers is correct.

Question 16

Which of the following pairs of amino acids is positively charged at a neutral pH?

Accepted Answer

A)  Lys, Arg 
B)  Tyr, Arg 
C)  Cys, Met 
D)  Leu, Pro 
E)  Asp, Glu 
A)  Lys, Arg 
B)  Tyr, Arg 
C)  Cys, Met 
D)  Leu, Pro 
E)  Asp, Glu

Question 17

Agents such as ______________________ and guanidinium chloride denature proteins by disrupting the noncovalent interactions.

Accepted Answer

The answer of Agents such as ______________________ and guanidinium chloride...

Question 18

Which of the following is a function of proteins?

Accepted Answer

A)  energy carrying molecules 
B)  catalysts 
C)  storage of genetic information 
D)  None of the answers is correct. 
E)  All of the answers are correct. 
A)  energy carrying molecules 
B)  catalysts 
C)  storage of genetic information 
D)  None of the answers is correct. 
E)  All of the answers are correct.

Question 19

Which individual won a Nobel Prize for his (her) landmark work in sequencing the protein insulin?

Accepted Answer

A)  Pauling 
B)  McClintock 
C)  Gilbert 
D)  Maxam 
E)  Sanger 
A)  Pauling 
B)  McClintock 
C)  Gilbert 
D)  Maxam 
E)  Sanger

Question 20

The configuration of most peptide bonds in a protein is _____.

Accepted Answer

A)  cis 
B)  circular 
C)  parallel 
D)  trans 
E)  perpendicular 
A)  cis 
B)  circular 
C)  parallel 
D)  trans 
E)  perpendicular

Exam 2: Protein Composition and Structure

What are the three aromatic amino acids?

The ________________________ β-sheet structure occurs when the two strands are oriented in the same directions (N →C).

A term that describes a molecule that contains both positive and negative charges but overall has a neutral charge is _____.

Formation of a peptide bond produces _____ as a byproduct.

What level of protein structure is composed of α\alphaα helices, β\betaβ sheets, and turns?

The overall three-dimensional structure of a single polypeptide is referred to as _____.

Why is the peptide bond planar?

______________________ is the major fibrous protein present in skin, bone, tendon, cartilage, and teeth.

Disulfide bonds in proteins can be reduced to free sulfhydryl groups by reagents such as _____________________.

What structure(s) did Pauling and Corey predict in 1951?

Which of the following amino acid residues would most likely be buried in the interior of a water-soluble, globular protein?

The term "quaternary" with respect to protein structure means

What is the advantage of having certain areas of partially correct folded regions?

What type of plot allows one to investigate the likely phi and psi angles of the peptide backbone?

Where are Ω and β turns and loops often found?

Which of the following pairs of amino acids is positively charged at a neutral pH?

Agents such as ______________________ and guanidinium chloride denature proteins by disrupting the noncovalent interactions.

Which of the following is a function of proteins?

Which individual won a Nobel Prize for his (her) landmark work in sequencing the protein insulin?

The configuration of most peptide bonds in a protein is _____.

Biochemistry: an Evolving Science

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Oxidative Phosphorylation

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, Repair, and Recombination

Rna Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters

What level of protein structure is composed of $\alpha$ helices, $\beta$ sheets, and turns?