Question 1

Why is enzyme replacement therapy with imiglucerase an effective treatment for some forms of Gaucher's disease?

Accepted Answer

A)  Imiglucerase breaks down glucocerebroside. 
B)  Imiglucerase regenerates deficient myeloperoxidase. 
C)  Imiglucerase facilitates the production of active cytochromes. 
D)  Imiglucerase breaks down fungi when the body is not able to. 
A)  Imiglucerase breaks down glucocerebroside. 
B)  Imiglucerase regenerates deficient myeloperoxidase. 
C)  Imiglucerase facilitates the production of active cytochromes. 
D)  Imiglucerase breaks down fungi when the body is not able to. A

Question 2

Some bacteria can avoid oxygen-dependent phagocytic killing by producing:

Accepted Answer

A)  Catalase 
B)  Defensins 
C)  Singlet oxygen 
D)  Superoxide dismutase 
A)  Catalase 
B)  Defensins 
C)  Singlet oxygen 
D)  Superoxide dismutase A

Question 3

Following phagocytic ingestion of a pathogen, which of the following occurs?

Accepted Answer

A)  Pinocytosis 
B)  Phagosome fusion with granules 
C)  Binding to antibody by Fc receptor on phagocyte 
D)  Binding to complement fragments by complement receptors 
A)  Pinocytosis 
B)  Phagosome fusion with granules 
C)  Binding to antibody by Fc receptor on phagocyte 
D)  Binding to complement fragments by complement receptors B

Question 4

Which is a key component in oxygen-independent phagocytic killing?

Accepted Answer

A)  Lysozyme 
B)  Myeloperoxidase 
C)  Hypochlorous acid 
D)  Superoxide dismutase 
A)  Lysozyme 
B)  Myeloperoxidase 
C)  Hypochlorous acid 
D)  Superoxide dismutase

Question 5

Patients with this disease are at greater risk for fungal infections than patients with other phagocytosis-related deficiencies:

Accepted Answer

A)  Gaucher's disease 
B)  Myeloperoxidase deficiency 
C)  Chronic granulomatous disease 
D)  Complement receptor deficiency 
A)  Gaucher's disease 
B)  Myeloperoxidase deficiency 
C)  Chronic granulomatous disease 
D)  Complement receptor deficiency

Question 6

What is the purpose of complement receptor binding to complement fragments during phagocytosis?

Accepted Answer

A)  Reduces production of ATP 
B)  Causes production of catalase 
C)  Triggers production of superoxide 
D)  Facilitates internalization of pathogen 
A)  Reduces production of ATP 
B)  Causes production of catalase 
C)  Triggers production of superoxide 
D)  Facilitates internalization of pathogen

Why is enzyme replacement therapy with imiglucerase an effective treatment for some forms of Gaucher's disease?

Some bacteria can avoid oxygen-dependent phagocytic killing by producing:

Following phagocytic ingestion of a pathogen, which of the following occurs?

Which is a key component in oxygen-independent phagocytic killing?

Patients with this disease are at greater risk for fungal infections than patients with other phagocytosis-related deficiencies:

What is the purpose of complement receptor binding to complement fragments during phagocytosis?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Complement

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

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Exam 12: Phagocytosis and Intracellular Killing

Why is enzyme replacement therapy with imiglucerase an effective treatment for some forms of Gaucher's disease?

Some bacteria can avoid oxygen-dependent phagocytic killing by producing:

Following phagocytic ingestion of a pathogen, which of the following occurs?

Which is a key component in oxygen-independent phagocytic killing?

Patients with this disease are at greater risk for fungal infections than patients with other phagocytosis-related deficiencies:

What is the purpose of complement receptor binding to complement fragments during phagocytosis?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Complement

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters