Question 1

An IgG2 subclass response is important for proper immunization with the meningococcal vaccine because:

Accepted Answer

A)  IgG2 responds better to protein antigens 
B)  IgG2 responds better to carbohydrate antigens 
C)  Other IgG subclasses do not activate complement as efficiently 
D)  Other IgG subclasses are not always induced following vaccination 
A)  IgG2 responds better to protein antigens 
B)  IgG2 responds better to carbohydrate antigens 
C)  Other IgG subclasses do not activate complement as efficiently 
D)  Other IgG subclasses are not always induced following vaccination B

Question 2

Which region of the antibody is important for physical flexibility of the antigen binding region?

Accepted Answer

A)  J chain 
B)  Hinge region 
C)  Secretory piece 
D)  Variable regions 
A)  J chain 
B)  Hinge region 
C)  Secretory piece 
D)  Variable regions B

Question 3

A patient has numerous skin lesions, including boils and abscesses, and has Staphylococcus aureus-induced lung disease. The patient also has coarse facial features and skeletal abnormalities. The patient exhibits high levels of IgE in the serum. The patient is most likely suffering from:

Accepted Answer

A)  Job syndrome 
B)  Multiple myeloma 
C)  Waldenstrom's macroglobulinemia 
D)  Common variable immunodeficiency (CVI
D)  
A)  Job syndrome 
B)  Multiple myeloma 
C)  Waldenstrom's macroglobulinemia 
D)  Common variable immunodeficiency (CVI
D)  A

Question 4

Antibodies with high affinity will be able to:

Accepted Answer

A)  Tightly bind lower concentrations of antigen and quickly eliminate infection 
B)  Tightly bind higher concentrations of antigen and quickly eliminate infection 
C)  Loosely bind to lower concentrations of antigen and slowly eliminate infection 
D)  Loosely bind to higher concentrations of antigen and slowly eliminate infection 
A)  Tightly bind lower concentrations of antigen and quickly eliminate infection 
B)  Tightly bind higher concentrations of antigen and quickly eliminate infection 
C)  Loosely bind to lower concentrations of antigen and slowly eliminate infection 
D)  Loosely bind to higher concentrations of antigen and slowly eliminate infection

Question 5

During the anamnestic response, IgM-producing plasma cells switch to producing which type of antibody?

Accepted Answer

A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG

Question 6

The monomeric form of this antibody inserted into the B cell membrane serves as the B cell receptor (BCR):

Accepted Answer

A)  IgA 
B)  IgE 
C)  IgG 
D)  IgM 
A)  IgA 
B)  IgE 
C)  IgG 
D)  IgM

Question 7

A patient has bone pain, high calcium levels, high immunoglobulin levels, and Bence Jones proteins in their urine. The most likely diagnosis for this patient is:

Accepted Answer

A)  Job syndrome 
B)  Multiple myeloma 
C)  Waldenstrom's macroglobulinemia 
D)  Common variable immunodeficiency (CVI
D)  
A)  Job syndrome 
B)  Multiple myeloma 
C)  Waldenstrom's macroglobulinemia 
D)  Common variable immunodeficiency (CVI
D)

Question 8

Fab fragments can be used clinically to treat:

Accepted Answer

A)  Job syndrome 
B)  Digoxin overdose 
C)  Multiple myeloma 
D)  Common variable immunodeficiency (CVI
D)  
A)  Job syndrome 
B)  Digoxin overdose 
C)  Multiple myeloma 
D)  Common variable immunodeficiency (CVI
D)

Question 9

Which of the following antibody regions is involved in antigen binding? 
I. Light chain variable region
II. Heavy chain variable region
III. Heavy chain constant region

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III

Question 10

Which class of antibody causes the release of histamine-containing granules of basophils and mast cells?

Accepted Answer

A)  IgA 
B)  IgE 
C)  IgG 
D)  IgM 
A)  IgA 
B)  IgE 
C)  IgG 
D)  IgM

An IgG2 subclass response is important for proper immunization with the meningococcal vaccine because:

Which region of the antibody is important for physical flexibility of the antigen binding region?

A patient has numerous skin lesions, including boils and abscesses, and has Staphylococcus aureus-induced lung disease. The patient also has coarse facial features and skeletal abnormalities. The patient exhibits high levels of IgE in the serum. The patient is most likely suffering from:

Antibodies with high affinity will be able to:

During the anamnestic response, IgM-producing plasma cells switch to producing which type of antibody?

The monomeric form of this antibody inserted into the B cell membrane serves as the B cell receptor (BCR):

A patient has bone pain, high calcium levels, high immunoglobulin levels, and Bence Jones proteins in their urine. The most likely diagnosis for this patient is:

Fab fragments can be used clinically to treat:

Which of the following antibody regions is involved in antigen binding? I. Light chain variable region II. Heavy chain variable region III. Heavy chain constant region

Which class of antibody causes the release of histamine-containing granules of basophils and mast cells?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibody Diversity

Complement

Phagocytosis and Intracellular Killing

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters

Exam 9: Antibodies

An IgG2 subclass response is important for proper immunization with the meningococcal vaccine because:

Which region of the antibody is important for physical flexibility of the antigen binding region?

A patient has numerous skin lesions, including boils and abscesses, and has Staphylococcus aureus-induced lung disease. The patient also has coarse facial features and skeletal abnormalities. The patient exhibits high levels of IgE in the serum. The patient is most likely suffering from:

Antibodies with high affinity will be able to:

During the anamnestic response, IgM-producing plasma cells switch to producing which type of antibody?

The monomeric form of this antibody inserted into the B cell membrane serves as the B cell receptor (BCR):

A patient has bone pain, high calcium levels, high immunoglobulin levels, and Bence Jones proteins in their urine. The most likely diagnosis for this patient is:

Fab fragments can be used clinically to treat:

Which of the following antibody regions is involved in antigen binding? I. Light chain variable region II. Heavy chain variable region III. Heavy chain constant region

Which class of antibody causes the release of histamine-containing granules of basophils and mast cells?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibody Diversity

Complement

Phagocytosis and Intracellular Killing

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters