Question 1

Radiolabeled antibodies to CD20, including tositumomab labeled with iodine-131, are frequently used to treat which disorder?

Accepted Answer

A)  Multiple myeloma 
B)  Rheumatoid arthritis 
C)  Non-Hodgkin's lymphoma 
D)  Human immunodeficiency virus (HIV) 
A)  Multiple myeloma 
B)  Rheumatoid arthritis 
C)  Non-Hodgkin's lymphoma 
D)  Human immunodeficiency virus (HIV) C

Question 2

The main pathological target for autoantibodies found in patients with Kawasaki disease is:

Accepted Answer

A)  Skin 
B)  Kidneys 
C)  Platelets 
D)  Vascular endothelial cells 
A)  Skin 
B)  Kidneys 
C)  Platelets 
D)  Vascular endothelial cells D

Question 3

A monoclonal antibody used as a drug has a name that ends in what suffix?

Accepted Answer

A)  U 
B)  Ab 
C)  Mab 
D)  Imm 
A)  U 
B)  Ab 
C)  Mab 
D)  Imm C

Question 4

Anti-Rh antibodies are used to treat:

Accepted Answer

A)  Serum sickness 
B)  Kawasaki disease 
C)  Erythroblastosis fetalis 
D)  Idiopathic thrombocytopenic purpura (ITP) 
A)  Serum sickness 
B)  Kawasaki disease 
C)  Erythroblastosis fetalis 
D)  Idiopathic thrombocytopenic purpura (ITP)

Question 5

A serious potential side effect of using antiserum therapy is the development of immune complexes that can lead to serious damage in the:

Accepted Answer

A)  Brain 
B)  Lungs 
C)  Muscles 
D)  Kidneys 
A)  Brain 
B)  Lungs 
C)  Muscles 
D)  Kidneys

Question 6

Chimeric antibodies are a combination of:

Accepted Answer

A)  Murine and yeast genes 
B)  Human and yeast genes 
C)  Human and murine genes 
D)  Murine genes from two different sources 
A)  Murine and yeast genes 
B)  Human and yeast genes 
C)  Human and murine genes 
D)  Murine genes from two different sources

Question 7

Low platelet count and antibodies to platelets are signs of:

Accepted Answer

A)  Serum sickness 
B)  Kawasaki disease 
C)  Erythroblastosis fetalis 
D)  Idiopathic thrombocytopenic purpura (ITP) 
A)  Serum sickness 
B)  Kawasaki disease 
C)  Erythroblastosis fetalis 
D)  Idiopathic thrombocytopenic purpura (ITP)

Question 8

Hybridomas are fusion cells composed of:

Accepted Answer

A)  B cells and T cells 
B)  Two different myeloma cells 
C)  Splenic B cells and myeloma cells 
D)  Lymph node B cells and splenic B cells 
A)  B cells and T cells 
B)  Two different myeloma cells 
C)  Splenic B cells and myeloma cells 
D)  Lymph node B cells and splenic B cells

Question 9

Bispecific antibodies can react with:

Accepted Answer

A)  Two different antigens 
B)  Two of the same antigen 
C)  Antigen and T cell or NK cell 
D)  Four different antigens on the same cell 
A)  Two different antigens 
B)  Two of the same antigen 
C)  Antigen and T cell or NK cell 
D)  Four different antigens on the same cell

Question 10

Which of the following is an example of active immunity?

Accepted Answer

A)  Antibody used therapeutically to treat lymphoma 
B)  Immunity to pneumococcal infection after exposure to the organism 
C)  Immunity acquired in a child by passage of antibodies from the mother's milk 
D)  Administration of pooled immunoglobulins from patients that had recovered from cytomegalovirus (CMV) to patients that currently have the disease 
A)  Antibody used therapeutically to treat lymphoma 
B)  Immunity to pneumococcal infection after exposure to the organism 
C)  Immunity acquired in a child by passage of antibodies from the mother's milk 
D)  Administration of pooled immunoglobulins from patients that had recovered from cytomegalovirus (CMV) to patients that currently have the disease

Radiolabeled antibodies to CD20, including tositumomab labeled with iodine-131, are frequently used to treat which disorder?

The main pathological target for autoantibodies found in patients with Kawasaki disease is:

A monoclonal antibody used as a drug has a name that ends in what suffix?

Anti-Rh antibodies are used to treat:

A serious potential side effect of using antiserum therapy is the development of immune complexes that can lead to serious damage in the:

Chimeric antibodies are a combination of:

Low platelet count and antibodies to platelets are signs of:

Hybridomas are fusion cells composed of:

Bispecific antibodies can react with:

Which of the following is an example of active immunity?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Complement

Phagocytosis and Intracellular Killing

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

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Exam 13: Antibodies and in Vivo Therapy

Radiolabeled antibodies to CD20, including tositumomab labeled with iodine-131, are frequently used to treat which disorder?

The main pathological target for autoantibodies found in patients with Kawasaki disease is:

A monoclonal antibody used as a drug has a name that ends in what suffix?

Anti-Rh antibodies are used to treat:

A serious potential side effect of using antiserum therapy is the development of immune complexes that can lead to serious damage in the:

Chimeric antibodies are a combination of:

Low platelet count and antibodies to platelets are signs of:

Hybridomas are fusion cells composed of:

Bispecific antibodies can react with:

Which of the following is an example of active immunity?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Complement

Phagocytosis and Intracellular Killing

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters