Question 1

Which of the following are methods by which the C3 complement component can be cleaved? 
I. Factor D
II. C3 convertase
III. Spontaneous cleavage

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III D

Question 2

Which of the following complement components acts as a chemoattractant?

Accepted Answer

A)  C2a 
B)  C3a 
C)  C4b 
D)  C5b 
A)  C2a 
B)  C3a 
C)  C4b 
D)  C5b B

Question 3

Patients with paroxysmal nocturnal hemoglobinuria lack which complement regulatory components on the host cell surfaces?

Accepted Answer

A)  Factor H and Factor I 
B)  Decay accelerating factor (DAF) and CD59 
C)  Membrane cofactor protein (MCP) and C1INH 
D)  Homologous restriction factor (HRF) and properdin 
A)  Factor H and Factor I 
B)  Decay accelerating factor (DAF) and CD59 
C)  Membrane cofactor protein (MCP) and C1INH 
D)  Homologous restriction factor (HRF) and properdin B

Question 4

In the alternative pathway, C3b can bind to which of the following? 
I. To C3bBb
II. To factor B
III. The microbe cell surface

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III

Question 5

The role that C3d plays in the immune response to pathogens is:

Accepted Answer

A)  Activation of B cells 
B)  Activation of CD4 and CD8 T cells 
C)  Activation of the alternative pathway 
D)  Activation of inhibitory factors of the complement pathways 
A)  Activation of B cells 
B)  Activation of CD4 and CD8 T cells 
C)  Activation of the alternative pathway 
D)  Activation of inhibitory factors of the complement pathways

Question 6

Which of the complement pathways requires antibodies for activation? 
I. Lectin pathway
II. Alternative pathway
III. Classical pathway

Accepted Answer

A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III 
A)  I only 
B)  III only 
C)  I and II 
D)  II and III 
E)  I, II, and III

Question 7

Which component is common to all three complement pathways?

Accepted Answer

A)  C1 
B)  C2 
C)  C3 
D)  C4 
A)  C1 
B)  C2 
C)  C3 
D)  C4

Question 8

What is the role of C9 in the complement pathways?

Accepted Answer

A)  Creates pore 
B)  C3 convertase 
C)  C5 convertase 
D)  Binds to antibodies on microbe surface 
A)  Creates pore 
B)  C3 convertase 
C)  C5 convertase 
D)  Binds to antibodies on microbe surface

Question 9

The role that C3bBb3b plays in the complement pathway is to:

Accepted Answer

A)  Cleave C2 to C2a and C2b 
B)  Cleave C3 to C3a and C3b 
C)  Cleave C4 to C4a and C4b 
D)  Cleave C5 to C5a and C5b 
A)  Cleave C2 to C2a and C2b 
B)  Cleave C3 to C3a and C3b 
C)  Cleave C4 to C4a and C4b 
D)  Cleave C5 to C5a and C5b

Question 10

Which of the following components can act as an opsonin?

Accepted Answer

A)  C1q 
B)  C3b 
C)  C4a 
D)  C5b 
A)  C1q 
B)  C3b 
C)  C4a 
D)  C5b

Which of the following are methods by which the C3 complement component can be cleaved? I. Factor D II. C3 convertase III. Spontaneous cleavage

Which of the following complement components acts as a chemoattractant?

Patients with paroxysmal nocturnal hemoglobinuria lack which complement regulatory components on the host cell surfaces?

In the alternative pathway, C3b can bind to which of the following? I. To C3bBb II. To factor B III. The microbe cell surface

The role that C3d plays in the immune response to pathogens is:

Which of the complement pathways requires antibodies for activation? I. Lectin pathway II. Alternative pathway III. Classical pathway

Which component is common to all three complement pathways?

What is the role of C9 in the complement pathways?

The role that C3bBb3b plays in the complement pathway is to:

Which of the following components can act as an opsonin?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Phagocytosis and Intracellular Killing

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

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Exam 11: Complement

Which of the following are methods by which the C3 complement component can be cleaved? I. Factor D II. C3 convertase III. Spontaneous cleavage

Which of the following complement components acts as a chemoattractant?

Patients with paroxysmal nocturnal hemoglobinuria lack which complement regulatory components on the host cell surfaces?

In the alternative pathway, C3b can bind to which of the following? I. To C3bBb II. To factor B III. The microbe cell surface

The role that C3d plays in the immune response to pathogens is:

Which of the complement pathways requires antibodies for activation? I. Lectin pathway II. Alternative pathway III. Classical pathway

Which component is common to all three complement pathways?

What is the role of C9 in the complement pathways?

The role that C3bBb3b plays in the complement pathway is to:

Which of the following components can act as an opsonin?

Cells and Organs of the Immune System

Innate Immunity

Immunogenicity and Antigenicity

Antigen Presenting Molecules

Antigen Presenting Cells

Surface Interactions Between T Cells and Antigen-Presenting Cells

Intracellular Signaling and T Cell Activation

B Cell Activation and Signaling

Antibodies

Antibody Diversity

Phagocytosis and Intracellular Killing

Antibodies and in Vivo Therapy

Antibodies and in Vitro Research and Diagnostic Assays

Immediate Allergic Reactions

Autoimmunity

Transplantation

Antigen Presentation for Cell-Mediated Response

Delayed Type Hypersensitivity Reactions

Cytotoxic T Cells

Natural Killer Cells

Factors That Influence the Immune Response

Cytokines and Biological Modifiers

Vaccines in Theory and Practice

Vaccine-Preventable Diseases

Acquired Immune Deficiency Syndrome

Filters