Exam 6: Microbial Genomics

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Chromosomal islands are presumed to have a "foreign" origin based upon three observations.What are these observations and how do they indicate that chromosomal islands are "foreign" in origin?

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The presence of a sequence flanked by inverted repeats suggests transposition brought in the sequence.An island is also likely "foreign" when there is a dissimilar composition of bases (GC%)or a different codon bias.Lastly,chromosomal islands typically contain genes that are related in function,such as virulence or biodegradation.

Heterotrophs need only a few more genes than autotrophs.

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Genes for DNA replication and transcription make up only a small fraction of the typical prokaryotic genome.

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Most mobile DNA consists of

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Compounds such as pyruvate,acetyl-CoA,fructose-6-phosphate,oxaloacetate,and other small organic compounds could be part of a(n)

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Summarize the evolution of sequencing technology beginning with the Sanger method.

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When compared with Bacteria,species of Archaea seem to devote a higher percentage of their genomes to genes encoding proteins involved in

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What process allows evolution to "experiment" with genes to create novel functions? How is this manifested in extant genes (presently existing)and their relationships to each other?

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Microorganisms that grow in extreme environments typically contain larger genomes when compared to microbes that grow in non-extreme environments.

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The 140 kbp genome containing many short repeats,ribosomal RNA genes,one RNA polymerase gene (rpo)and one RubisCO gene (rbcL)is most likely from a(n)

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The evolutionary origin of mitochondria is demonstrated by which of the following key genomic characteristics?

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Genomic analysis led to the discovery that pathogenic organisms often lack genes for amino acid biosynthesis.

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Codon usage and even the genetic code itself varies from one organism to the next.

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The pan genome of a species is the genomic content that is

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Explain horizontal gene transfer and demonstrate how this phenomenon has complicated evolutionary studies using a diagram that illustrates phylogenetic relationships between organisms and genes.

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Comparative genomics helps us to understand evolutionary relationships between organisms.

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Mobile DNA elements are more common in the genomes of

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Explain how codon bias and GC content can be used to detect horizontal gene transfer within a genome.

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Genes from different sources that are related in sequence due to shared evolutionary ancestry are called ________ genes,and groups of such genes are known as ________.

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Transcriptome analysis is useful in relation to genome analysis because

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