Exam 22: Genomics I: Analysis of DNA

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_________ involves an examination of how the proteins encoded by genes interact to produce cell and tissue types.

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A

Which of the following is the most direct benefit of high-throughput Sanger sequencing?

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D

The term that best describes how the components of a genome interact to produce an organism's traits is:

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B

Which of the following acronyms describes a technique used in chromosome painting?

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In sequencing by synthesis (SBS) methods, the sequence of a sample is directly determined as nucleotides are incorporated into a DNA strand by DNA polymerase.

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Which of the following procedures best determines the relative order, but not precise location, of a series of genes on a chromosome?

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If all members of a population have the identical DNA sequence at a given site, that site is said to be _______.

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An RFLP marker may be used to predict the likelihood that an individual carries a trait for a specific disease.

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A site that has variation within the members of the population is said to be ________.

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Map units correspond to fixed physical distances.

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Metagenomics is a common approach for studying the genes of a clonal population of bacteria in the laboratory.

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Cytogenetic mapping is accurate to within 500,000 base pairs, but not over this value.

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The process of in situ hybridization is used for which of the following ?

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A series of clones that contain overlapping pieces of a chromosome are called a _______.

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YAC stands for yeast artificial cosmid.

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Which of the following samples would NOT be suitable for a metagenomics-based approach?

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What does physical mapping provide that the other types of genetic mapping do not?

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________ uses the unique banding patterns of a chromosome to determine the general location of a gene.

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BAC stands for bacterial artificial chromosome.

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In a FISH procedure, the probe being used is labeled with a fluorescent tag.

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