Exam 24: Medical Genetics and Cancer

Prions can contain either DNA or RNA as their genetic material.

Dizygotic twins share _______ of their genetic information.

Haplotypes between homologs in the same individual _________; haplotypes for the same chromosome in different individuals ________.

When a scientist is attempting to use haplotype analysis to link a disease-causing allele to a molecular marker, it is important for the marker to be close to the disease-causing allele, otherwise _____ may occur.

The first acutely transforming virus to be isolated was _____.

What is p53?

The age at which a disease appears in an organism is called the _______.

In a disease that is associated with a single recessive allele, the concordance among dizygotic twins should be ____, assuming both parents are heterozygous carriers.

A pedigree analysis is the study of family trees to establish patterns of inheritance.

In the United States, most newborns undergo a test for primary congenital hypothyroidism, a condition where people are unable to produce enough thyroid hormone. On a nationwide basis, this is an example of

In a cell culture you notice that a group of cells have begun to form a focus on a culture dish. These cells are most likely ______.

A disease that can be caused by mutations in different genes is said to have homogeneity.

An oncogene may promote cancer by keeping the cell growth pathway in the off position.

The majority of human cancers are caused by ______.

You are analyzing a human pedigree for a new disease and discover that the disease occurs with the same frequency in both sexes and that 25% of the children from two unaffected heterozygous parents have the disease. This disease is displaying ____ inheritance.

When are caspases active?

When GTP is bound to Ras, it is in the _____ form.

Programmed cell death is called genome maintenance.

Checkpoint proteins act as ________.

You are working in a lab where you are studying a disease that is known to be caused by a single nucleotide change, although the effect this change ultimately has on the protein's structure/function is unknown. You have DNA samples from multiple patients that you suspect of having this disease. What is the most efficient way to test the samples for the relevant mutation?