Question 1

In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can begin during meiosis.

Accepted Answer

A) True 
 B)False  False

Question 2

The integrase enzyme is responsible for inserting bacteriophage $\lambda$ into the host genome.

Accepted Answer

A) True 
 B)False  True

Question 3

Transposons that utilize an RNA intermediate for transposition are called _____.

Accepted Answer

A) IS elements 
B) Retroviruses 
C) Retrotransposons 
D) Non-transposable elements 
A) IS elements 
B) Retroviruses 
C) Retrotransposons 
D) Non-transposable elements C

Question 4

The human genome contains a unique gene for each immunoglobulin produced.

Accepted Answer

A) True 
 B)False

Question 5

Site-specific recombination occurs between homologous sequences of DNA.

Accepted Answer

A) True 
 B)False

Question 6

Recombination between sister chromatids produces new combinations of alleles that may be beneficial to the species.

Accepted Answer

A) True 
 B)False

Question 7

Which enzyme is unique to the retro elements?

Accepted Answer

A) Reverse transcriptase 
B) Reverse resolvase 
C) Transposase 
D) Integrase 
E) Reverse integrase 
A) Reverse transcriptase 
B) Reverse resolvase 
C) Transposase 
D) Integrase 
E) Reverse integrase

Question 8

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Accepted Answer

A) Ds 
B) C 
C) Sh 
D) Wx 
E) All of the answers are correct 
A) Ds 
B) C 
C) Sh 
D) Wx 
E) All of the answers are correct

Question 9

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Accepted Answer

A) A nick in only one strand of the DNA 
B) Double-stranded breaks in DNA 
C) DNA gap repair synthesis 
D) Heteroduplex formation 
A) A nick in only one strand of the DNA 
B) Double-stranded breaks in DNA 
C) DNA gap repair synthesis 
D) Heteroduplex formation

Question 10

What is the selfish DNA theory?

Accepted Answer

A) A theory that explains how DNA point mutations are repaired within the genome. 
B) A theory that explains how transposable elements are repaired within the genome. 
C) A theory that attempts to explain the proliferation of transposable elements in a genome by comparing it to the action of a parasite. 
D) A theory that attempts to explain how the proliferation of transposons improves the evolutionary advantage of the host organism. 
A) A theory that explains how DNA point mutations are repaired within the genome. 
B) A theory that explains how transposable elements are repaired within the genome. 
C) A theory that attempts to explain the proliferation of transposable elements in a genome by comparing it to the action of a parasite. 
D) A theory that attempts to explain how the proliferation of transposons improves the evolutionary advantage of the host organism.

Question 11

Long-terminal repeats are unique to which group of transposons?

Accepted Answer

A) Composite transposon 
B) Non-viral retro element 
C) Viral-like retro element 
D) Replicative transposon 
E) Insertion sequence 
A) Composite transposon 
B) Non-viral retro element 
C) Viral-like retro element 
D) Replicative transposon 
E) Insertion sequence

Question 12

The process of recombination occurs during metaphase I of meiosis.

Accepted Answer

A) True 
 B)False

Question 13

The formation of a D-loop is associated with which of the following models of recombination?

Accepted Answer

A) Double-stranded break model 
B) Holliday model 
C) Single-stranded break model 
A) Double-stranded break model 
B) Holliday model 
C) Single-stranded break model

Question 14

To date, there are not any indications that transposable elements offer a selective advantage to a species.

Accepted Answer

A) True 
 B)False

Question 15

Transposable elements in bacteria are commonly called insertion sequences.

Accepted Answer

A) True 
 B)False

Question 16

Which of the following may account for the process of gene conversion?

Accepted Answer

A) DNA mismatch repair 
B) DNA gap repair 
C) Photolyase activity 
D) Nucleotide excision repair 
A) DNA mismatch repair 
B) DNA gap repair 
C) Photolyase activity 
D) Nucleotide excision repair

Question 17

A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

Accepted Answer

A) True 
 B)False

Question 18

A heteroduplex is a DNA double helix that contains mismatches.

Accepted Answer

A) True 
 B)False

Question 19

Which of the following enzymes is required for a transposon to move?

Accepted Answer

A) Integrase 
B) Jumpase 
C) Splicase 
D) Transposase 
A) Integrase 
B) Jumpase 
C) Splicase 
D) Transposase

Question 20

Which of the following best describes the function of the RecA protein in

Accepted Answer

A) Promotes strand invasion and formation of the D loop 
B) Recognizes double-stranded breaks in the DNA 
C) Is involved in the initial formation of the Holliday junctions 
D) Resolves Holliday junctions into separate chromosomes 
E) coli recombination? 
A) Promotes strand invasion and formation of the D loop 
B) Recognizes double-stranded breaks in the DNA 
C) Is involved in the initial formation of the Holliday junctions 
D) Resolves Holliday junctions into separate chromosomes 
E) coli recombination?

Exam 19: Recombination and Transposition at the Molecular Level

In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can begin during meiosis.

The integrase enzyme is responsible for inserting bacteriophage λ\lambdaλ into the host genome.

Transposons that utilize an RNA intermediate for transposition are called _____.

The human genome contains a unique gene for each immunoglobulin produced.

Site-specific recombination occurs between homologous sequences of DNA.

Recombination between sister chromatids produces new combinations of alleles that may be beneficial to the species.

Which enzyme is unique to the retro elements?

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

What is the selfish DNA theory?

Long-terminal repeats are unique to which group of transposons?

The process of recombination occurs during metaphase I of meiosis.

The formation of a D-loop is associated with which of the following models of recombination?

To date, there are not any indications that transposable elements offer a selective advantage to a species.

Transposable elements in bacteria are commonly called insertion sequences.

Which of the following may account for the process of gene conversion?

A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

A heteroduplex is a DNA double helix that contains mismatches.

Which of the following enzymes is required for a transposon to move?

Which of the following best describes the function of the RecA protein in

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Variation in Chromosome Structure and Number

Molecular Structure of DNA and RNA

Chromosome Organization and Molecular Structure

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

DNA Technologies

Biotechnology

Genomics I: Analysis of DNA

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

Filters

The integrase enzyme is responsible for inserting bacteriophage $\lambda$ into the host genome.