Question 1

Homologous genes within a species are called paralogs.

Accepted Answer

A) True 
 B)False  True

Question 2

A loss of an internal piece of a chromosome is called a __________.

Accepted Answer

A) reciprocal translocation 
B) terminal deficiency 
C) interstitial deletion 
D) gene duplication 
A) reciprocal translocation 
B) terminal deficiency 
C) interstitial deletion 
D) gene duplication C

Question 3

The majority of autosomal aneuploid conditions are lethal, but sex chromosome aneuploids are usually not lethal.

Accepted Answer

A) True 
 B)False  True

Question 4

_______ is a drug that is used to experimentally produce polyploidy in organisms.

Accepted Answer

A)  Penicillin 
B)  Colchicine 
C)  Polymosca 
D)  Karyocine 
A)  Penicillin 
B)  Colchicine 
C)  Polymosca 
D)  Karyocine

Question 5

An inversion heterozygote contains

Accepted Answer

A) two homologous chromosomes with inversions. 
B) two normal chromosomes. 
C) one normal chromosome and one chromosome with an inversion. 
D) None of the answers are correct 
A) two homologous chromosomes with inversions. 
B) two normal chromosomes. 
C) one normal chromosome and one chromosome with an inversion. 
D) None of the answers are correct

Question 6

Klinefelter and Turner syndromes are examples of

Accepted Answer

A) sex chromosome aneuploidy. 
B) autosomal aneuploidy. 
C) reciprocal translocations. 
D) paracentric inversions. 
A) sex chromosome aneuploidy. 
B) autosomal aneuploidy. 
C) reciprocal translocations. 
D) paracentric inversions.

Question 7

Which of the following is not an example of euploidy?

Accepted Answer

A) Tetraploid 
B) Polyploid 
C) Triploid 
D) Diploid 
E) Aneuploid 
A) Tetraploid 
B) Polyploid 
C) Triploid 
D) Diploid 
E) Aneuploid

Question 8

The effects of a deficiency on an organism is dependent on the size of the deletion and the importance of the missing genetic material to the organism.

Accepted Answer

A) True 
 B)False

Question 9

Given the following sequence of genes on a chromosome, determine what change in chromosome structure occurred. (the * indicates the centromere) before A B C D * E F G H
After A C D * E F G H

Accepted Answer

A)  Terminal deletion 
B)  Interstitial deletion 
C)  Inversion 
D)  Gene duplication 
A)  Terminal deletion 
B)  Interstitial deletion 
C)  Inversion 
D)  Gene duplication

Question 10

A diploid organism has a total of 36 chromosomes. Assuming all possible chromosome combinations are viable, if a mutant tetraploid version of this organism was created how many chromosomes would it have? If a mutant version of this organism was monosomic for chromosome 9 how many chomosomes would it have?

Accepted Answer

A) 144; 35 
B) 72; 35 
C) 144; 37 
D) 72; 37 
A) 144; 35 
B) 72; 35 
C) 144; 37 
D) 72; 37

Question 11

A _______ translocation represents when a piece of one chromosome is attached to another chromosome.

Accepted Answer

A)  simple 
B)  complex 
C)  reciprocal 
D)  balanced 
A)  simple 
B)  complex 
C)  reciprocal 
D)  balanced

Question 12

The production of gene families, such as the globin genes is the result of ________.

Accepted Answer

A) inversions 
B) deficiencies 
C) gene duplications 
D) simple translocations 
E) None of the answers are correct 
A) inversions 
B) deficiencies 
C) gene duplications 
D) simple translocations 
E) None of the answers are correct

Question 13

Edward and Patau syndromes are examples of __________.

Accepted Answer

A) aneuploidy 
B) allopolyploidy 
C) autopolyploidy 
D) translocations 
A) aneuploidy 
B) allopolyploidy 
C) autopolyploidy 
D) translocations

Question 14

Given the following sequence of genes on a chromosome, determine what change in chromosome structure occurred. (the * indicates the centromere) before A B C D * E F G H
After A B C D * E F E F G H

Accepted Answer

A) Terminal deficiency 
B) Interstitial deficiency 
C) Inversion 
D) Gene duplication 
A) Terminal deficiency 
B) Interstitial deficiency 
C) Inversion 
D) Gene duplication

Question 15

A wholphin is a rare hybrid animal born from mating a female bottlenose dolphin with a male false killer whale. Wholphins are diploid. Interestingly, wholphins are fertile. What can you conclude from the fact that wholphins are fertile?

Accepted Answer

A) Wholphins are allotetraploid. 
B) Dolphins and false killer whales likely have the same number of chromosomes. 
C) Dolphins and false killer whales are actually the same species. 
D) One of the parents must have been aneuploid. 
A) Wholphins are allotetraploid. 
B) Dolphins and false killer whales likely have the same number of chromosomes. 
C) Dolphins and false killer whales are actually the same species. 
D) One of the parents must have been aneuploid.

Question 16

Hemophilia A is an X-linked blood clotting disorder. A normal man and a woman with hemophilia A have a child with Turner Syndrome. This child does not have hemophilia. In whom did non-disjunction occur? In meiosis I or meiosis II?

Accepted Answer

A) Woman; meiosis I 
B) Woman; meiosis II 
C) Man; meiosis I 
D) Man; meiosis II 
E)  Woman; there is not enough information to tell if the nondisjunction happened in meiosis I or II. 
A) Woman; meiosis I 
B) Woman; meiosis II 
C) Man; meiosis I 
D) Man; meiosis II 
E)  Woman; there is not enough information to tell if the nondisjunction happened in meiosis I or II.

Question 17

Translocations and inversions represent a change in the total genetic material of a chromosome.

Accepted Answer

A) True 
 B)False

Question 18

A translocation cross may occur in an individual that has a(n)

Accepted Answer

A) reciprocal translocation. 
B) unbalanced translocation. 
C) simple translocation. 
D) All of the answers are correct 
A) reciprocal translocation. 
B) unbalanced translocation. 
C) simple translocation. 
D) All of the answers are correct

Question 19

Human genetic diseases such a Cri-du-chat, Angelman syndrome and Prader-Willi syndrome are the result of which type of chromosomal change?

Accepted Answer

A) Translocations 
B) Duplications 
C) Deletions 
D) Inversions 
A) Translocations 
B) Duplications 
C) Deletions 
D) Inversions

Question 20

Which algebraic expression would be used to denote a trisomic organism?

Accepted Answer

A) 3n 
B) 2n - 1 
C) 2n + 1 
D) 2n + 2 
A) 3n 
B) 2n - 1 
C) 2n + 1 
D) 2n + 2

Exam 8: Variation in Chromosome Structure and Number

Homologous genes within a species are called paralogs.

A loss of an internal piece of a chromosome is called a __________.

The majority of autosomal aneuploid conditions are lethal, but sex chromosome aneuploids are usually not lethal.

_______ is a drug that is used to experimentally produce polyploidy in organisms.

An inversion heterozygote contains

Klinefelter and Turner syndromes are examples of

Which of the following is not an example of euploidy?

The effects of a deficiency on an organism is dependent on the size of the deletion and the importance of the missing genetic material to the organism.

Given the following sequence of genes on a chromosome, determine what change in chromosome structure occurred. (the * indicates the centromere) before A B C D * E F G H After A C D * E F G H

A _______ translocation represents when a piece of one chromosome is attached to another chromosome.

The production of gene families, such as the globin genes is the result of ________.

Edward and Patau syndromes are examples of __________.

Given the following sequence of genes on a chromosome, determine what change in chromosome structure occurred. (the * indicates the centromere) before A B C D * E F G H After A B C D * E F E F G H

A wholphin is a rare hybrid animal born from mating a female bottlenose dolphin with a male false killer whale. Wholphins are diploid. Interestingly, wholphins are fertile. What can you conclude from the fact that wholphins are fertile?

Hemophilia A is an X-linked blood clotting disorder. A normal man and a woman with hemophilia A have a child with Turner Syndrome. This child does not have hemophilia. In whom did non-disjunction occur? In meiosis I or meiosis II?

Translocations and inversions represent a change in the total genetic material of a chromosome.

A translocation cross may occur in an individual that has a(n)

Human genetic diseases such a Cri-du-chat, Angelman syndrome and Prader-Willi syndrome are the result of which type of chromosomal change?

Which algebraic expression would be used to denote a trisomic organism?

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Molecular Structure of DNA and RNA

Chromosome Organization and Molecular Structure

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular Level

DNA Technologies

Biotechnology

Genomics I: Analysis of DNA

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

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