Question 1

In the gene that affects snail coiling, the ______ is responsible for the phenotype of the offspring.

Accepted Answer

A)  mother's phenotype 
B)  father's phenotype 
C)  mother's genotype 
D)  father's genotype 
A)  mother's phenotype 
B)  father's phenotype 
C)  mother's genotype 
D)  father's genotype C

Question 2

What is a disease associated with extra nuclear inheritance?

Accepted Answer

A) Angelman Syndrome 
B) Prader-Willi Syndrome 
C) LHON 
D) Muscular Dystrophy 
A) Angelman Syndrome 
B) Prader-Willi Syndrome 
C) LHON 
D) Muscular Dystrophy C

Question 3

If the sperm cell contributes mitochondria to the oocyte, it is called _______.

Accepted Answer

A)  paternal leakage 
B)  maternal leakage 
C)  paternal inheritance 
D)  mitochondria 
E)  imprinting 
A)  paternal leakage 
B)  maternal leakage 
C)  paternal inheritance 
D)  mitochondria 
E)  imprinting A

Question 4

What type of inheritance is observed with extranuclear DNA?

Accepted Answer

A) Mendelian inheritance 
B) Sex-linked inheritance 
C) Paternal inheritance 
D) Maternal inheritance 
E)  Maternal effect 
A) Mendelian inheritance 
B) Sex-linked inheritance 
C) Paternal inheritance 
D) Maternal inheritance 
E)  Maternal effect

Question 5

mtDNA stands for _______ and cpDNA stands for _______.

Accepted Answer

A)  extranuclear DNA, cytoplasmic DNA 
B)  maternal DNA, paternal DNA 
C)  marked DNA, copied DNA 
D)  nuclear, cytoplasmic 
E)  mitochondrial DNA, chloroplast DNA 
A)  extranuclear DNA, cytoplasmic DNA 
B)  maternal DNA, paternal DNA 
C)  marked DNA, copied DNA 
D)  nuclear, cytoplasmic 
E)  mitochondrial DNA, chloroplast DNA

Question 6

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called _______.

Accepted Answer

A) extranuclear inheritance 
B) maternal effect 
C) imprinting 
D) nuclear 
E) epigenetic 
A) extranuclear inheritance 
B) maternal effect 
C) imprinting 
D) nuclear 
E) epigenetic

Question 7

What is the molecular mechanism for imprinting a gene?

Accepted Answer

A) Acetylation 
B) Nitration 
C) Phosphorylation 
D) Methylation 
A) Acetylation 
B) Nitration 
C) Phosphorylation 
D) Methylation

Question 8

What genes appear to be controlled by the Xic?

Accepted Answer

A) Xist and Tsix 
B) Xist only 
C) Tsix only 
D) None of these 
A) Xist and Tsix 
B) Xist only 
C) Tsix only 
D) None of these

Question 9

Which diseases are associated with imprinting?

Accepted Answer

A) Angelman Syndrome 
B) LHON 
C) Alzheimer's Disease 
D) All of the answers are correct 
A) Angelman Syndrome 
B) LHON 
C) Alzheimer's Disease 
D) All of the answers are correct

Question 10

How many Barr bodies would an individual with a XXY genotype possess?

Accepted Answer

A) 0 
B) 1 
C) 2 
D) None of the answers are correct 
A) 0 
B) 1 
C) 2 
D) None of the answers are correct

Question 11

Where is extranuclear DNA located in mammalian cells?

Accepted Answer

A) Endoplasmic reticulum 
B) Mitochondria 
C) Ribosome 
D) Plasma membrane 
A) Endoplasmic reticulum 
B) Mitochondria 
C) Ribosome 
D) Plasma membrane

Question 12

In which cells do erasure and re-establishment of imprinting marks typically NOT occur?

Accepted Answer

A) Nurse cells 
B) Sperm cells 
C) Oocytes 
D) Somatic cells 
A) Nurse cells 
B) Sperm cells 
C) Oocytes 
D) Somatic cells

Question 13

Dosage compensation offsets the problems associated with differences in the number of _______ chromosomes in many species.

Accepted Answer

A)  cytoplasmic 
B)  autosome 
C)  sex 
D)  extranuclear 
E)  mitochondrial 
A)  cytoplasmic 
B)  autosome 
C)  sex 
D)  extranuclear 
E)  mitochondrial

Question 14

In the Igf2 gene, which allele is imprinted? Which is expressed?

Accepted Answer

A) Paternal, paternal 
B) Paternal, maternal 
C) Maternal, paternal 
D) Maternal, maternal 
A) Paternal, paternal 
B) Paternal, maternal 
C) Maternal, paternal 
D) Maternal, maternal

Question 15

Heteroplasmy is associated with inheritance patterns involving

Accepted Answer

A)  nuclear. 
B)  paternal DNA. 
C)  chloroplasts. 
D)  ribosomes. 
E)  imprinted. 
A)  nuclear. 
B)  paternal DNA. 
C)  chloroplasts. 
D)  ribosomes. 
E)  imprinted.

Question 16

What encodes the toxin paramecin in Paramecia aurelia?

Accepted Answer

A) mtDNA 
B) cpDNA 
C) Nuclear DNA 
D) Kappa particles 
A) mtDNA 
B) cpDNA 
C) Nuclear DNA 
D) Kappa particles

Question 17

Which of the following is primarily responsible for the maternal effect?

Accepted Answer

A) Sperm cells 
B) Oocytes 
C) Nurse cells 
D) Placenta 
A) Sperm cells 
B) Oocytes 
C) Nurse cells 
D) Placenta

Question 18

What gene is most responsible for X-inactivation?

Accepted Answer

A) Xic 
B) Xist 
C) Tsix 
D) Xce 
A) Xic 
B) Xist 
C) Tsix 
D) Xce

Question 19

Most imprinted genes are silenced. What is one exception to this rule?

Accepted Answer

A) H19 
B) Igf2 
C) UBE3A 
D) SNRPN 
A) H19 
B) Igf2 
C) UBE3A 
D) SNRPN

Question 20

Which of the following is false regarding mtDNA?

Accepted Answer

A)  It is around 17,000 bp in length 
B)  It is a linear chromosome 
C)  Multiple copies exist in each mitochondria 
D)  It mostly contains rRNA and tRNA genes 
A)  It is around 17,000 bp in length 
B)  It is a linear chromosome 
C)  Multiple copies exist in each mitochondria 
D)  It mostly contains rRNA and tRNA genes

Exam 5: Non-Mendelian Inheritance

In the gene that affects snail coiling, the ______ is responsible for the phenotype of the offspring.

What is a disease associated with extra nuclear inheritance?

If the sperm cell contributes mitochondria to the oocyte, it is called _______.

What type of inheritance is observed with extranuclear DNA?

mtDNA stands for _______ and cpDNA stands for _______.

The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called _______.

What is the molecular mechanism for imprinting a gene?

What genes appear to be controlled by the Xic?

Which diseases are associated with imprinting?

How many Barr bodies would an individual with a XXY genotype possess?

Where is extranuclear DNA located in mammalian cells?

In which cells do erasure and re-establishment of imprinting marks typically NOT occur?

Dosage compensation offsets the problems associated with differences in the number of _______ chromosomes in many species.

In the Igf2 gene, which allele is imprinted? Which is expressed?

Heteroplasmy is associated with inheritance patterns involving

What encodes the toxin paramecin in Paramecia aurelia?

Which of the following is primarily responsible for the maternal effect?

What gene is most responsible for X-inactivation?

Most imprinted genes are silenced. What is one exception to this rule?

Which of the following is false regarding mtDNA?

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and Bacteriophages

Variation in Chromosome Structure and Number

Molecular Structure of DNA and RNA

Chromosome Organization and Molecular Structure

DNA Replication

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional Regulation

Gene Regulation in Eukaryotes II: Epigenetics and Regulation at the RNA Level

Genetics of Viruses

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular Level

DNA Technologies

Biotechnology

Genomics I: Analysis of DNA

Genomics II: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

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mtDNA stands for _ and cpDNA stands for _.