Question 1

What is the common strategy by which catalysis occurs?

Accepted Answer

A)  increasing the probability of product formation 
B)  shifting the reaction equilibrium 
C)  stabilization of transition state 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  increasing the probability of product formation 
B)  shifting the reaction equilibrium 
C)  stabilization of transition state 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 2

When the kcat / KM ratio is at its upper limit,it is referred to as

Accepted Answer

A)  Circe limits. 
B)  Michaelis rate. 
C)  kinetic perfection. 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  Circe limits. 
B)  Michaelis rate. 
C)  kinetic perfection. 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 3

Which of the following is true under the following conditions: the enzyme concentration is 5 nM,the substrate concentration is 5 mM,and the KM is 5 $\mu$M?

Accepted Answer

A)  The enzyme is saturated with substrate. 
B)  Most of the enzyme does not have substrate bound. 
C)  There is more enzyme than substrate. 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  The enzyme is saturated with substrate. 
B)  Most of the enzyme does not have substrate bound. 
C)  There is more enzyme than substrate. 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 4

.What is the upper limit of kcat / KM?

Accepted Answer

The diffusion-controlled interaction of

Question 5

What are transition-state analogs?

Accepted Answer

These potent inhibitors mimic the struct

Question 6

Allosteric enzymes can be identified because the plot of initial velocity,V0,versus substrate concentration,S,is not hyperbolic but __________________ -shaped.

Accepted Answer

Question 7

Multiple substrate enzyme reactions are divided into two classes which are called

Accepted Answer

A)  sequential displacement and double displacement. 
B)  double displacement and concerted displacement. 
C)  sequential displacement and concerted displacement. 
D)  sequential displacement and double as well as sequential displacement and concerted displacement are correct. 
E)  None of the answers is correct. 
A)  sequential displacement and double displacement. 
B)  double displacement and concerted displacement. 
C)  sequential displacement and concerted displacement. 
D)  sequential displacement and double as well as sequential displacement and concerted displacement are correct. 
E)  None of the answers is correct.

Question 8

When substrate concentration is much greater than KM,the rate of catalysis is almost equal to

Accepted Answer

A)  Kd. 
B)  kcat / KM.  
C)  Vmax. 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  Kd. 
B)  kcat / KM.  
C)  Vmax. 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 9

What type(s)of inhibition can be reversed?

Accepted Answer

A)  competitive 
B)  noncompetitive 
C)  mixed 
D)  All of the answers are correct. 
E)  None of the answers is correct. 
A)  competitive 
B)  noncompetitive 
C)  mixed 
D)  All of the answers are correct. 
E)  None of the answers is correct.

Question 10

In an enzymatic reaction in a test tube,the reaction will eventually reach equilibrium.Why does this not happen in living organisms?

Accepted Answer

In a cell,the product may be u

Exam 8: Enzymes: Basic Concepts and Kinetics

What is the common strategy by which catalysis occurs?

When the kcat / KM ratio is at its upper limit,it is referred to as

Which of the following is true under the following conditions: the enzyme concentration is 5 nM,the substrate concentration is 5 mM,and the KM is 5 μ\muμ M?

.What is the upper limit of kcat / KM?

What are transition-state analogs?

Allosteric enzymes can be identified because the plot of initial velocity,V0,versus substrate concentration,S,is not hyperbolic but __________________ -shaped.

Multiple substrate enzyme reactions are divided into two classes which are called

When substrate concentration is much greater than KM,the rate of catalysis is almost equal to

What type(s)of inhibition can be reversed?

In an enzymatic reaction in a test tube,the reaction will eventually reach equilibrium.Why does this not happen in living organisms?

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, repair, and Recombination

RNA Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

Filters

When the k_cat / K_M ratio is at its upper limit,it is referred to as

Which of the following is true under the following conditions: the enzyme concentration is 5 nM,the substrate concentration is 5 mM,and the K_M is 5 $\mu$ M?

.What is the upper limit of k_cat / K_M?

Allosteric enzymes can be identified because the plot of initial velocity,V₀,versus substrate concentration,S,is not hyperbolic but __________________ -shaped.

When substrate concentration is much greater than K_M,the rate of catalysis is almost equal to