Question 1

Describe the structure and function of the histone octamer.

Accepted Answer

The winding of DNA around a core of eigh

Question 2

Which of the following elements is found in the active site of the Argonaute-miRNA complex?

Accepted Answer

A)  magnesium 
B)  calcium 
C)  zinc 
D)  iron 
E)  copper 
A)  magnesium 
B)  calcium 
C)  zinc 
D)  iron 
E)  copper

Question 3

What phenomenon allows for the generation of multiple distinct cell types?

Accepted Answer

A)  combinatorial control 
B)  enhancer control 
C)  promoter control 
D)  epigenetic control 
E)  None of the answers is correct. 
A)  combinatorial control 
B)  enhancer control 
C)  promoter control 
D)  epigenetic control 
E)  None of the answers is correct.

Question 4

How does a coactivator function in gene expression?

Accepted Answer

The binding of ligand to the receptor in

Question 5

Describe the arrangement of histones and associated DNA in a nucleosome.

Accepted Answer

Two copies of each of the four histone p

Question 6

Seventy percent of the cytosines in human DNA are modified by methylation specifically in _______________ sequences.

Accepted Answer

The answer of Seventy percent of the cytosines in human...

Question 7

Histone binding and wrapping of DNA reduces the DNA length by

Accepted Answer

A)  2-fold. 
B)  7-fold. 
C)  20-fold. 
D)  100-fold. 
E)  1000-fold. 
A)  2-fold. 
B)  7-fold. 
C)  20-fold. 
D)  100-fold. 
E)  1000-fold.

Question 8

What are binding sites,present on DNA,that bind regulatory proteins,resulting in an increased level of transcription for a gene that is distant from the binding site?

Accepted Answer

A)  promoter 
B)  enhancer 
C)  augmenter 
D)  amplifier 
E)  enlarger 
A)  promoter 
B)  enhancer 
C)  augmenter 
D)  amplifier 
E)  enlarger

Question 9

What are the requirements for binding of the bromodomain to the transcriptional machinery?

Accepted Answer

The bromodomain is also known as the ace

Question 10

Which of the following are ways in which eukaryotic gene expression is more complex than prokaryotic gene expression?

Accepted Answer

A)  different cell types that express only a subset of the genes in the genome 
B)  the lack of DNA binding proteins to direct gene expression 
C)  the inaccessibility of the DNA in chromatin 
D)  A and B are correct. 
E)  A and C are correct. 
A)  different cell types that express only a subset of the genes in the genome 
B)  the lack of DNA binding proteins to direct gene expression 
C)  the inaccessibility of the DNA in chromatin 
D)  A and B are correct. 
E)  A and C are correct.

Exam 32: The Control of Gene Expression in Eukaryotes

Describe the structure and function of the histone octamer.

Which of the following elements is found in the active site of the Argonaute-miRNA complex?

What phenomenon allows for the generation of multiple distinct cell types?

How does a coactivator function in gene expression?

Describe the arrangement of histones and associated DNA in a nucleosome.

Seventy percent of the cytosines in human DNA are modified by methylation specifically in _______________ sequences.

Histone binding and wrapping of DNA reduces the DNA length by

What are binding sites,present on DNA,that bind regulatory proteins,resulting in an increased level of transcription for a gene that is distant from the binding site?

What are the requirements for binding of the bromodomain to the transcriptional machinery?

Which of the following are ways in which eukaryotic gene expression is more complex than prokaryotic gene expression?

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, repair, and Recombination

RNA Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

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