Question 1

Match each scientist with the appropriate immunological discovery.
-Phagocytosis

Accepted Answer

A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright 
A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright A

Question 2

Pasteur's discovery that older bacterial cultures would not cause disease in chickens but would protect them from subsequent infection with more virulent strains is an example of:

Accepted Answer

A)  attenuated vaccine. 
B)  natural immunity. 
C)  passive immunity. 
D)  cross-immunity. 
A)  attenuated vaccine. 
B)  natural immunity. 
C)  passive immunity. 
D)  cross-immunity. A

Question 3

All of the following cells are considered part of natural immunity EXCEPT:

Accepted Answer

A)  eosinophils. 
B)  B lymphocytes. 
C)  monocytes. 
D)  neutrophils. 
A)  eosinophils. 
B)  B lymphocytes. 
C)  monocytes. 
D)  neutrophils. B

Question 4

Primary lymphoid organs include which of the following?

Accepted Answer

A)  Spleen 
B)  Tonsils 
C)  Thymus 
D)  Lymph nodes 
A)  Spleen 
B)  Tonsils 
C)  Thymus 
D)  Lymph nodes

Question 5

The function of NK cells is to:

Accepted Answer

A)  produce antibody. 
B)  phagocytize bacteria. 
C)  present antigen to T cells. 
D)  kill target cells such as tumor and virally infected cells. 
A)  produce antibody. 
B)  phagocytize bacteria. 
C)  present antigen to T cells. 
D)  kill target cells such as tumor and virally infected cells.

Question 6

Eosinophils are involved in the immune response against:

Accepted Answer

A)  viruses. 
B)  intracellular bacteria. 
C)  parasites that cannot be phagocytized. 
D)  extracellular bacteria. 
A)  viruses. 
B)  intracellular bacteria. 
C)  parasites that cannot be phagocytized. 
D)  extracellular bacteria.

Question 7

The process by which leukocytes are attracted to a specific area by chemical messengers is called:

Accepted Answer

A)  diapedesis. 
B)  degranulation. 
C)  chemotaxis. 
D)  opsonization. 
A)  diapedesis. 
B)  degranulation. 
C)  chemotaxis. 
D)  opsonization.

Question 8

Acquired (adaptive)immunity can be characterized as:

Accepted Answer

A)  nonspecifically activated. 
B)  immediately responsive. 
C)  neutrophil dependent. 
D)  involving memory. 
A)  nonspecifically activated. 
B)  immediately responsive. 
C)  neutrophil dependent. 
D)  involving memory.

Question 9

B cells that are actively responding to antigen can be found in the:

Accepted Answer

A)  peripheral blood. 
B)  primary follicles. 
C)  germinal centers. 
D)  bone marrow. 
A)  peripheral blood. 
B)  primary follicles. 
C)  germinal centers. 
D)  bone marrow.

Question 10

Contact with antigen and activation of B cells normally occurs in the:

Accepted Answer

A)  peripheral blood. 
B)  connective tissue. 
C)  thymus. 
D)  lymph nodes. 
A)  peripheral blood. 
B)  connective tissue. 
C)  thymus. 
D)  lymph nodes.

Question 11

The ability to resist infection through normally present body functions best characterizes:

Accepted Answer

A)  autoimmunity. 
B)  natural immunity. 
C)  acquired immunity. 
D)  alloimmunity. 
A)  autoimmunity. 
B)  natural immunity. 
C)  acquired immunity. 
D)  alloimmunity.

Question 12

Which of the following is a characteristic of natural killer cells?

Accepted Answer

A)  They mature in the thymus. 
B)  They are smaller than B and T cells. 
C)  They are a type of lymphocyte. 
D)  They are part of the adaptive immune system. 
A)  They mature in the thymus. 
B)  They are smaller than B and T cells. 
C)  They are a type of lymphocyte. 
D)  They are part of the adaptive immune system.

Question 13

T cells are mainly concentrated in which region of the lymph nodes?

Accepted Answer

A)  Primary follicles 
B)  Secondary follicles 
C)  Paracortex 
D)  Medulla 
A)  Primary follicles 
B)  Secondary follicles 
C)  Paracortex 
D)  Medulla

Question 14

All of the following are commonly found within non-lymphoid tissues EXCEPT:

Accepted Answer

A)  B cells. 
B)  macrophages. 
C)  mast cells. 
D)  dendritic cells. 
A)  B cells. 
B)  macrophages. 
C)  mast cells. 
D)  dendritic cells.

Question 15

Which of the following is NOT a characteristic of neutrophils?

Accepted Answer

A)  Congregate in the marginating pool in blood vessels 
B)  Capable of diapedesis 
C)  Granules that become bright orange with Wright stain 
D)  Segmented nucleus 
A)  Congregate in the marginating pool in blood vessels 
B)  Capable of diapedesis 
C)  Granules that become bright orange with Wright stain 
D)  Segmented nucleus

Question 16

All of the following are considered part of natural immunity EXCEPT:

Accepted Answer

A)  eosinophils. 
B)  lymphocytes. 
C)  acute-phase reactants. 
D)  neutrophils. 
A)  eosinophils. 
B)  lymphocytes. 
C)  acute-phase reactants. 
D)  neutrophils.

Question 17

The most effective phagocytic and antigen-presenting cell is the:

Accepted Answer

A)  neutrophil. 
B)  monocyte. 
C)  dendritic cell. 
D)  macrophage. 
A)  neutrophil. 
B)  monocyte. 
C)  dendritic cell. 
D)  macrophage.

Question 18

Antibodies are secreted by:

Accepted Answer

A)  plasma cells. 
B)  B cells. 
C)  T cells. 
D)  dendritic cells. 
A)  plasma cells. 
B)  B cells. 
C)  T cells. 
D)  dendritic cells.

Question 19

"Cluster of differentiation" refers to:

Accepted Answer

A)  a category of cell surface proteins used to identify cell types. 
B)  aggregates of differentiating stem cells. 
C)  groups of antigens that identify a cell as foreign. 
D)  the cells that congregate in germinal centers. 
A)  a category of cell surface proteins used to identify cell types. 
B)  aggregates of differentiating stem cells. 
C)  groups of antigens that identify a cell as foreign. 
D)  the cells that congregate in germinal centers.

Question 20

Which of the following is characteristic of mucosal-associated lymphoid tissue?

Accepted Answer

A)  It is one of the primary lymphoid organs. 
B)  It clears pathogens from the bloodstream. 
C)  It includes the tonsils and the appendix. 
D)  It includes the liver and spleen. 
A)  It is one of the primary lymphoid organs. 
B)  It clears pathogens from the bloodstream. 
C)  It includes the tonsils and the appendix. 
D)  It includes the liver and spleen.

Exam 1: Introduction to Immunity and the Immune System

Match each scientist with the appropriate immunological discovery. -Phagocytosis

Pasteur's discovery that older bacterial cultures would not cause disease in chickens but would protect them from subsequent infection with more virulent strains is an example of:

All of the following cells are considered part of natural immunity EXCEPT:

Primary lymphoid organs include which of the following?

The function of NK cells is to:

Eosinophils are involved in the immune response against:

The process by which leukocytes are attracted to a specific area by chemical messengers is called:

Acquired (adaptive)immunity can be characterized as:

B cells that are actively responding to antigen can be found in the:

Contact with antigen and activation of B cells normally occurs in the:

The ability to resist infection through normally present body functions best characterizes:

Which of the following is a characteristic of natural killer cells?

T cells are mainly concentrated in which region of the lymph nodes?

All of the following are commonly found within non-lymphoid tissues EXCEPT:

Which of the following is NOT a characteristic of neutrophils?

All of the following are considered part of natural immunity EXCEPT:

The most effective phagocytic and antigen-presenting cell is the:

Antibodies are secreted by:

"Cluster of differentiation" refers to:

Which of the following is characteristic of mucosal-associated lymphoid tissue?

Nature of Antigens and the Major Histocompatibility Complex

Innate Immunity

Adaptive Immunity

Antibody Structure and Function

Cytokines

Complement System

Safety and Quality Management

Principles of Serological Testing

Precipitation and Agglutination Reactions

Labeled Immunoassays

Molecular Diagnostic Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Transplantation Immunology

Tumor Immunology

Immunoproliferative Diseases

Immunodeficiency Diseases

Serological and Molecular Detection of Bacterial Infections

Spirochete Diseases

Serological and Molecular Diagnosis of Parasitic and Fungal Infections

Serology and Molecular Detection of Viral Infections

Laboratory Diagnosis of HIV Infection

Immunization and Vaccines

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