Exam 9: Principles of Serological Testing

A new assay is used to test 120 samples from patients with a clinically confirmed diagnosis of the relevant infection and 50 samples from healthy control subjects.The test results were positive for 90 of the infected patients and positive for 10 of the healthy controls. -Calculate the assay's specificity.

Serology is the study of:

A blowout pipette would be labeled:

The probability that a person with a positive screening test actually has the disease screened for is called:

When 0.5 mL of serum is added to 1.5 mL of diluent,what dilution does this represent?

If 0.9 mL of saline is added to 0.1 mL of serum,what does the 0.9 mL represent?

A new assay is used to test 120 samples from patients with a clinically confirmed diagnosis of the relevant infection and 50 samples from healthy control subjects.The test results were positive for 90 of the infected patients and positive for 10 of the healthy controls. -What is the sensitivity of the assay?

Which series of dilutions would be best in order to make a 1:3000 dilution?

If you want to make 4 mL of a 1:20 dilution,how much serum would be needed?

An antibody titer is defined as the reciprocal of the:

A blood sample is processed,and the resulting serum is pink.This indicates:

A patient's serum must be added to a series of test tubes,but a different volume of serum must be added to each tube.If a single pipette is used,what kind is it?

The concentration of a solution is reduced by adding:

A new assay is used to test 120 samples from patients with a clinically confirmed diagnosis of the relevant infection and 50 samples from healthy control subjects.The test results were positive for 90 of the infected patients and positive for 10 of the healthy controls. -If the assay was used to test a different population consisting of 240 infected patients and 50 healthy controls,which assay parameter would increase?

What type of pipette must be blown out to deliver the exact volume of liquid?

How should a 1:50 dilution be made if the final volume needed is 10 mL?

If complement interferes with test results,the serum sample should be:

If there will be an unavoidable 4-hour delay before a serum sample can be tested,the sample should be:

On a serial dilution with the following tubes set up,1:2,1:4,1:8,1:16,1:32,and 1:64,there is no visible agglutination in the 1:64 tube.What is the titer of the antibody?

To prepare 70 ml of a 10% solution of acetic acid,how much acetic acid is needed?