Question 1

The human genome contains a unique gene for each immunoglobulin produced.

Accepted Answer

A) True 
 B)False  False

Question 2

Transposase is involved with removing the transposable element from its current location.

Accepted Answer

A) True 
 B)False  True

Question 3

All transposable elements are also autonomous elements

Accepted Answer

A) True 
 B)False  False

Question 4

High numbers of LINEs and SINEs may be due to transposable element activity.

Accepted Answer

A) True 
 B)False

Question 5

The process of recombination occurs during metaphase I of meiosis.

Accepted Answer

A) True 
 B)False

Question 6

Which of the following is an application of transposon tagging?

Accepted Answer

A)  To test if a transposon is replicative 
B)  As a tool to clone novel genes 
C)  To track the movement of transposons between species 
D)  To inactivate transposons in a genome 
A)  To test if a transposon is replicative 
B)  As a tool to clone novel genes 
C)  To track the movement of transposons between species 
D)  To inactivate transposons in a genome

Question 7

Long-terminal repeats are unique to which group of transposons?

Accepted Answer

A)  Composite transposon 
B)  Non-viral retro element 
C)  Viral-like retro element 
D)  Replicative transposon 
E)  Insertion sequence 
A)  Composite transposon 
B)  Non-viral retro element 
C)  Viral-like retro element 
D)  Replicative transposon 
E)  Insertion sequence

Question 8

Which of the following may account for the process of gene conversion?

Accepted Answer

A)  DNA mismatch repair 
B)  Retrotransposition 
C)  Photolyase activity 
D)  Nucleotide excision repair 
A)  DNA mismatch repair 
B)  Retrotransposition 
C)  Photolyase activity 
D)  Nucleotide excision repair

Question 9

RAG1 and RAG2 proteins are associated with which of the following?

Accepted Answer

A)  Recombination during prophase I of meiosis 
B)  Nucleotide excision repair 
C)  Transposition 
D)  Integration of a bacteriophage into the host genome 
E)  Site-specific recombination in antibody genes 
A)  Recombination during prophase I of meiosis 
B)  Nucleotide excision repair 
C)  Transposition 
D)  Integration of a bacteriophage into the host genome 
E)  Site-specific recombination in antibody genes

Question 10

A heteroduplex is a DNA double helix that contains mismatches.

Accepted Answer

A) True 
 B)False

Question 11

Which of the following best describes the function of the RecA protein in E. coli recombination?

Accepted Answer

A)  Promotes strand invasion and formation of the D loop 
B)  Recognizes double-stranded breaks in the DNA 
C)  Is involved in the initial formation of the Holliday junctions 
D)  Resolves Holliday junctions into separate chromosomes 
A)  Promotes strand invasion and formation of the D loop 
B)  Recognizes double-stranded breaks in the DNA 
C)  Is involved in the initial formation of the Holliday junctions 
D)  Resolves Holliday junctions into separate chromosomes

Question 12

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Accepted Answer

A)  Ds 
B)  C 
C)  Sh 
D)  Wx 
E)  All of the answers are correct 
A)  Ds 
B)  C 
C)  Sh 
D)  Wx 
E)  All of the answers are correct

Question 13

Which of the following processes accounts for the tremendous variation in antibody structure?

Accepted Answer

A)  RNA editing 
B)  Site-specific recombination 
C)  Integrase activity 
D)  Physiological adaptation 
E)  Hot spots of mutation in the immunoglobin genes 
A)  RNA editing 
B)  Site-specific recombination 
C)  Integrase activity 
D)  Physiological adaptation 
E)  Hot spots of mutation in the immunoglobin genes

Question 14

The formation of a D-loop is associated with which of the following models of recombination?

Accepted Answer

A)  Double-stranded break model 
B)  Holliday model 
C)  Single-stranded break model 
A)  Double-stranded break model 
B)  Holliday model 
C)  Single-stranded break model

Question 15

Transposons that utilize an RNA intermediate for transposition are called ________.

Accepted Answer

A)  IS elements 
B)  Retroviruses 
C)  Retrotransposons 
D)  Non-transposable elements 
A)  IS elements 
B)  Retroviruses 
C)  Retrotransposons 
D)  Non-transposable elements

Question 16

Ty is an example of a retrotransposon

Accepted Answer

A) True 
 B)False

Question 17

Direct Repeats

Accepted Answer

A)  are also called target-site duplications 
B)  are oriented in the same direction 
C)  are adjacent to both ends of any TE 
D)  all of the above are true 
A)  are also called target-site duplications 
B)  are oriented in the same direction 
C)  are adjacent to both ends of any TE 
D)  all of the above are true

Question 18

In E. coli, a mutation in the genes encoding which of the following proteins would disable the ability of the cell to recognize double-stranded breaks and conduct recombination during meiosis?

Accepted Answer

A)  RecG 
B)  RecA 
C)  RecBCD 
D)  RuvABC 
A)  RecG 
B)  RecA 
C)  RecBCD 
D)  RuvABC

Question 19

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Accepted Answer

A)  A nick in only one strand of the DNA 
B)  Double-stranded breaks in DNA 
C)  DNA gap repair synthesis 
D)  Heteroduplex formation 
A)  A nick in only one strand of the DNA 
B)  Double-stranded breaks in DNA 
C)  DNA gap repair synthesis 
D)  Heteroduplex formation

Question 20

Which of the following enzymes is required for a transposon to move?

Accepted Answer

A)  Integrase 
B)  Jumpase 
C)  Splicase 
D)  Transposase 
A)  Integrase 
B)  Jumpase 
C)  Splicase 
D)  Transposase

Exam 20: Recombination, Immunogenetics, and Transposition

The human genome contains a unique gene for each immunoglobulin produced.

Transposase is involved with removing the transposable element from its current location.

All transposable elements are also autonomous elements

High numbers of LINEs and SINEs may be due to transposable element activity.

The process of recombination occurs during metaphase I of meiosis.

Which of the following is an application of transposon tagging?

Long-terminal repeats are unique to which group of transposons?

Which of the following may account for the process of gene conversion?

RAG1 and RAG2 proteins are associated with which of the following?

A heteroduplex is a DNA double helix that contains mismatches.

Which of the following best describes the function of the RecA protein in E. coli recombination?

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Which of the following processes accounts for the tremendous variation in antibody structure?

The formation of a D-loop is associated with which of the following models of recombination?

Transposons that utilize an RNA intermediate for transposition are called ________.

Ty is an example of a retrotransposon

Direct Repeats

In E. coli, a mutation in the genes encoding which of the following proteins would disable the ability of the cell to recognize double-stranded breaks and conduct recombination during meiosis?

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Which of the following enzymes is required for a transposon to move?

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional and Translation Regulation

Gene Regulation in Eukaryotes Ii: Epigenetics

Non-Coding Rnas

Genetics of Viruses

Gene Mutation and Dna Repair

Molecular Technologies

Biotechnology

Genomics I: Analysis of Dna

Genomics Ii: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Complex and Quantitative Traits

Evolutionary Genetics

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