Exam 10: Cell and Tissue Architecture: Cytoskeleton, Cell Junctions, and Extracellular Matrix

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Dynamic instability of microtubules:

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Suppose there is a mutation in a laminin-binding integrin gene that causes a loss of function in the cytoplasmic domains of the integrin. Which of the following would you expect to observe as a result of this mutation?

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Which one of the following statements about intracellular transport is TRUE?

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Where would you find a cell adhesion molecule?

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Could an isolated melanin granule move along an actin microfilament?

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The property of dynamic instability implies that the individual protein subunits of microtubules are held together by:

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Which one of the following statements about intracellular transport is TRUE?

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Metastatic cancer cells:

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Which of the following cytoskeletal elements contribute to the structural integrity and strength of epithelial tissues in animals?

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Which of the following is a component of the extracellular matrix produced by an animal cell?

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A decrease in cell adhesion, by the introduction of an experimental substance to a tissue, compromises the structural integrity of the tissue. Which cell junction would MOST likely be affected by this treatment causing a decrease in the strength of the tissue?

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Which is the correct order of cytoskeletal filaments in DECREASING filament diameter?

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Which one of the following statements about intracellular transport is TRUE?

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Which type of cellular junction(s) allow(s) for the movement of proteins and transfer RNA molecules?

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Why are the ends of microfilaments and microtubules called "plus ends" and "minus ends"?

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What would happen in a cell if its a-tubulin was mutated and unable to bind to its b tubulin?

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The extracellular matrix is a network of:

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Cell junctions composed of cadherins organized as points of adhesion between adjacent cells and that connect to intermediate filaments are referred to as _____.

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An epithelial tissue is defined as a:

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What is the BEST characterization of the minus end of a dynamic filament?

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