Exam 37: Role of the Kidneys in the Regulation of Acid-Base Balance

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A 60-year-old woman comes to the emergency department with shortness of breath.An arterial blood sample is obtained,and the following data are noted: Partial pressure of oxygen (Po2): 75 mm Hg (normal: 75 to 100 mm Hg) Pco2: 58 mm Hg (normal: 33 to 44 mm Hg) [HCO3]: 24 mEq/L (normal: 22 to 28 mEq/L) PH: 7.24 (normal: 7.35 to 7.45) What is the acid-base disorder?

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In response to metabolic acidosis,the kidneys increase the excretion of net acid.Which of the following is the most important component of this compensatory response?

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An individual with a 20-year history of smoking three packs/day who has emphysema has the following data: pH = 7.37; [HCO3] = 28 mEq/L; Pco2 = 50 mm Hg.Which acid-base disturbance is consistent with this clinical scenario and these arterial blood gas measurements?

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An individual with diabetes mellitus who forgets to take insulin has the following data: pH = 7.29; [HCO3] = 12 mEq/L; Pco2 = 26 mm Hg.Which acid-base disturbance is consistent with this clinical scenario and these arterial blood gas measurements?

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An individual with cardiopulmonary arrest has the following data: pH = 6.85; [HCO3] = 10 mEq/L; Pco2 = 60 mm Hg.Which acid-base disturbance is consistent with this clinical scenario and these arterial blood gas measurements?

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An individual with an asthma attack; has the following data: pH = 7.32; [HCO3] = 25 mEq/L; partial pressure of carbon dioxide (Pco2)= 50 mm Hg.Which acid-base disturbance is consistent with this clinical scenario and these arterial blood gas measurements?

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An individual with a gastric ulcer who ingests large quantities of antacids has the following data: pH = 7.45; [HCO3] = 30 mEq/L; Pco2 = 45 mm Hg.Which acid-base disturbance is consistent with this clinical scenario and these arterial blood gas measurements?

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A 6-year-old boy presents to the emergency department with fever,abdominal cramps,and diarrhea.Arterial blood gas measurements are as follows: pH: 7.28 (normal: 7.35 to 7.45) Pco2: 24 mm Hg (normal: 33 to 44 mm Hg) [HCO3]: 11 mEq/L (normal: 22 to 28 mEq/L) What is the acid-base disorder?

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During a 24-hour period,an individual excretes in the urine 60 mmol of NH4+,40 mmol of titratable acid,and 10 mmol of HCO3.If this individual is in acid-base balance,how much nonvolatile acid was produced from metabolism?

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