Exam 17: DNA Replication, repair, and Recombination

A 40-year-old patient has been diagnosed with cancer.Sequencing of cancer cell genomes reveals a high frequency of G/C to A/T base pairs conversion.The DNA repair system that is most likely deficient in this patient is the

Insertion and deletion mutations can be caused by

In DNA replication,the leading strand of DNA ________,while the other newly forming strand,called the lagging strand,________.

The type of DNA repair that fixes mistakes in nucleotide incorporation after DNA replication is known as ________ repair.

It has been observed that when plants are subjected to extreme physical stress such as drought or high salinity,the transcription and activity of transposase genes increases.Increased transposase activity may

The DNA polymerase reaction occurs in the ________ as incoming nucleotides are added to ________ end(s)of the growing DNA chain.

Which of the following DNA repair mechanisms is most prone to error?

Transposase is

Which of the following do not undergo theta replication?

Nonhomologous end joining is used to

Cells that are very sensitive to UV radiation most likely have a defect in the

Which of the following eukaryotic DNA polymerases replicates mitochondrial DNA?

DNA repair in eukaryotes and prokaryotes

A way of making multiple copies of a segment of DNA from a single template (without culturing cells)is known as ________.

DNA replication

Thymine is used in DNA despite the fact that it is energetically more expensive to synthesize than uracil because

Each of the following are associated with replicons except

The energy needed to polymerize DNA is supplied by

Small pieces of DNA synthesized on the lagging strand are called ________.

Base excision repair is used to