Question 1

What is graft- versus- host disease?

Accepted Answer

A)  It occurs when tissue from an isograft is rejected. 
B)  It occurs when tissue from an allograft is rejected. 
C)  Immune system cells of the host attack the newly transplanted bone marrow and reject it. 
D)  Immune system cells in transplanted bone marrow attack the body of its new host. 
E)  It occurs when tissue from a xenograft is rejected. 
A)  It occurs when tissue from an isograft is rejected. 
B)  It occurs when tissue from an allograft is rejected. 
C)  Immune system cells of the host attack the newly transplanted bone marrow and reject it. 
D)  Immune system cells in transplanted bone marrow attack the body of its new host. 
E)  It occurs when tissue from a xenograft is rejected. D

Question 2

Health care providers determine the specific allergen that is generating symptoms by using a blood test to look at _ _ levels.

Accepted Answer

A)  IgD 
B)  IgA 
C)  IgE 
D)  IgM 
E)  IgG 
A)  IgD 
B)  IgA 
C)  IgE 
D)  IgM 
E)  IgG C

Question 3

The blood type AB+ is referred to as the universal donor.

Accepted Answer

A) True 
 B)False  False

Question 4

What two types of patients help demonstrate that cancer can be considered a failure of the immune system?

Accepted Answer

A)  rheumatoid arthritis patients and multiple sclerosis patients 
B)  nervous system complication patients and pulmonary system complication patients 
C)  transplant patients and HIV/AIDS patients 
D)  hepatitis C infected patients and human papilloma viruses infected patients 
E)  migraine patients and digestive issue patients 
A)  rheumatoid arthritis patients and multiple sclerosis patients 
B)  nervous system complication patients and pulmonary system complication patients 
C)  transplant patients and HIV/AIDS patients 
D)  hepatitis C infected patients and human papilloma viruses infected patients 
E)  migraine patients and digestive issue patients

Question 5

Localized anaphylaxis tends to feature isolated symptoms such as

Accepted Answer

A)  fainting, chest pain, or vomiting. 
B)  anxiety, nausea, or swelling. 
C)  decreased blood pressure, shortness of breath, or abdominal pain. 
D)  confusion, hives, or hoarseness. 
E)  watery eyes, a runny nose, or a confined rash. 
A)  fainting, chest pain, or vomiting. 
B)  anxiety, nausea, or swelling. 
C)  decreased blood pressure, shortness of breath, or abdominal pain. 
D)  confusion, hives, or hoarseness. 
E)  watery eyes, a runny nose, or a confined rash.

Question 6

An allergen is any antigen that triggers IgE production and leads to a scenario where the immune system fights off a perceived threat that would otherwise be harmless.

Accepted Answer

A) True 
 B)False

Question 7

Allografts are

Accepted Answer

A)  transplants that are made in an immune- privileged site in the body are the least likely to be rejected. 
B)  transplants from self, like a self- skin graft from one part of the body to another location. 
C)  transplanted tissue from an identical twin. 
D)  interspecies transplants. 
E)  similar to the host, but not genetically identical. 
A)  transplants that are made in an immune- privileged site in the body are the least likely to be rejected. 
B)  transplants from self, like a self- skin graft from one part of the body to another location. 
C)  transplanted tissue from an identical twin. 
D)  interspecies transplants. 
E)  similar to the host, but not genetically identical.

Question 8

Immune complex reactions belong to which class of hypersensitivity reactions?

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  type V 
A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  type V

Question 9

In desensitization immunotherapy, an antigen is used to stimulate cell 2, which can then stimulate cell 3 and cause the production of item 4. Identify cell 2, cell 3 and item 4.

Accepted Answer

A)  T helper 1 cell, T helper 2 cell, and IgG antibodies 
B)  mast cell, T helper 2 cell, and IgE antibodies 
C)  T regulatory cell, T helper 2 cell, and IgE antibodies 
D)  T regulatory cell, T helper 1 cell, and IgG antibodies 
E)  T regulatory cell, mast cell, and IgD antibodies 
A)  T helper 1 cell, T helper 2 cell, and IgG antibodies 
B)  mast cell, T helper 2 cell, and IgE antibodies 
C)  T regulatory cell, T helper 2 cell, and IgE antibodies 
D)  T regulatory cell, T helper 1 cell, and IgG antibodies 
E)  T regulatory cell, mast cell, and IgD antibodies

Question 10

Why are type IV hypersensitivities called delayed hypersensitivity reactions?

Accepted Answer

A)  Drugs to counteract type IV reactions are large and slow to be absorbed by the affected cells causing the patient to tolerate a lengthy symptomatic phase before recovery is complete. 
B)  Although type IV reactions can cause skin lesions, watery eyes, and a runny nose, treatment for those symptoms needs to be delayed due to the rapid drop in blood pressure which soon follows and needs to be dealt with first. 
C)  Type IV reactions affect nerve cells and cause nerve impulses to slow resulting in visibly slower movements from the patient. 
D)  Type IV reactions manifest slowly over 12- 72 hours after the stimulating antigen is encountered. 
E)  Type IV reactions only occur in underdeveloped countries and medical attention often needs to be delayed until the patient can be brought to a hospital. 
A)  Drugs to counteract type IV reactions are large and slow to be absorbed by the affected cells causing the patient to tolerate a lengthy symptomatic phase before recovery is complete. 
B)  Although type IV reactions can cause skin lesions, watery eyes, and a runny nose, treatment for those symptoms needs to be delayed due to the rapid drop in blood pressure which soon follows and needs to be dealt with first. 
C)  Type IV reactions affect nerve cells and cause nerve impulses to slow resulting in visibly slower movements from the patient. 
D)  Type IV reactions manifest slowly over 12- 72 hours after the stimulating antigen is encountered. 
E)  Type IV reactions only occur in underdeveloped countries and medical attention often needs to be delayed until the patient can be brought to a hospital.

Question 11

Desensitization immunotherapies are least effective to treat allergies from which of the following?

Accepted Answer

A)  fire ant stings 
B)  milk 
C)  pollen 
D)  bee stings 
E)  dust mites 
A)  fire ant stings 
B)  milk 
C)  pollen 
D)  bee stings 
E)  dust mites

Question 12

Which of the following are used to treat serum sickness?

Accepted Answer

A)  anti- inflammatory drugs 
B)  sulfa drugs 
C)  antihistamines 
D)  anti- inflammatory drugs and antihistamines 
E)  anti- inflammatory drugs, antihistamines, and sulfa drugs 
A)  anti- inflammatory drugs 
B)  sulfa drugs 
C)  antihistamines 
D)  anti- inflammatory drugs and antihistamines 
E)  anti- inflammatory drugs, antihistamines, and sulfa drugs

Question 13

The erythrocyte sedimentation rate is used to monitor

Accepted Answer

A)  anemia. 
B)  inflammation. 
C)  pregnancy. 
D)  declining health in aging patients. 
E)  infectious status. 
A)  anemia. 
B)  inflammation. 
C)  pregnancy. 
D)  declining health in aging patients. 
E)  infectious status.

Question 14

Which of the following examples of type II hypersensitivities are matched incorrectly with their mediated mechanism?

Accepted Answer

A)  rheumatic heart disease: cytolytic 
B)  myasthenia gravis: noncytolytic 
C)  Graves' disease: noncytolytic 
D)  Goodpasture syndrome: noncytolytic 
E)  hemolytic disease of the newborn: cytolytic 
A)  rheumatic heart disease: cytolytic 
B)  myasthenia gravis: noncytolytic 
C)  Graves' disease: noncytolytic 
D)  Goodpasture syndrome: noncytolytic 
E)  hemolytic disease of the newborn: cytolytic

Question 15

Which of the following hypersensitivities are T cell- mediated responses against self- antigens or otherwise harmless antigens?

Accepted Answer

A)  type I hypersensitivities and type II hypersensitivities 
B)  type III hypersensitivities 
C)  type II hypersensitivities 
D)  type I hypersensitivities 
E)  type IV hypersensitivities 
A)  type I hypersensitivities and type II hypersensitivities 
B)  type III hypersensitivities 
C)  type II hypersensitivities 
D)  type I hypersensitivities 
E)  type IV hypersensitivities

Question 16

Which of the following would not cause serum sickness?

Accepted Answer

A)  anti- inflammatory drugs 
B)  penicillin 
C)  antivenom 
D)  sulfa drugs 
E)  antitoxin 
A)  anti- inflammatory drugs 
B)  penicillin 
C)  antivenom 
D)  sulfa drugs 
E)  antitoxin

Question 17

Autoimmune disorders are diagnosed using

Accepted Answer

A)  metabolic factors. 
B)  detection of autoantibodies. 
C)  family history. 
D)  a collection of tests and careful assessment of signs and symptoms. 
E)  blood tests. 
A)  metabolic factors. 
B)  detection of autoantibodies. 
C)  family history. 
D)  a collection of tests and careful assessment of signs and symptoms. 
E)  blood tests.

Question 18

An allergy is a scenario where the immune system fights off a perceived threat that would otherwise eventually cause the breakdown of skin or other localized tissue.

Accepted Answer

A) True 
 B)False

Question 19

A patient that experiences a tuberculin skin test reaction is experiencing which class of hypersensitivity reactions?

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  type V 
A)  type I 
B)  type II 
C)  type III 
D)  type IV 
E)  type V

Question 20

If the patient has an allergy to the tested allergen, then the skin develops a lesion consisting of a flattened reddened area called the wheal and a raised, inflamed area called the flare.

Accepted Answer

A) True 
 B)False

Exam 13: Immune System Disorders

What is graft- versus- host disease?

Health care providers determine the specific allergen that is generating symptoms by using a blood test to look at _ _ levels.

The blood type AB+ is referred to as the universal donor.

What two types of patients help demonstrate that cancer can be considered a failure of the immune system?

Localized anaphylaxis tends to feature isolated symptoms such as

An allergen is any antigen that triggers IgE production and leads to a scenario where the immune system fights off a perceived threat that would otherwise be harmless.

Allografts are

Immune complex reactions belong to which class of hypersensitivity reactions?

In desensitization immunotherapy, an antigen is used to stimulate cell 2, which can then stimulate cell 3 and cause the production of item 4. Identify cell 2, cell 3 and item 4.

Why are type IV hypersensitivities called delayed hypersensitivity reactions?

Desensitization immunotherapies are least effective to treat allergies from which of the following?

Which of the following are used to treat serum sickness?

The erythrocyte sedimentation rate is used to monitor

Which of the following examples of type II hypersensitivities are matched incorrectly with their mediated mechanism?

Which of the following hypersensitivities are T cell- mediated responses against self- antigens or otherwise harmless antigens?

Which of the following would not cause serum sickness?

Autoimmune disorders are diagnosed using

An allergy is a scenario where the immune system fights off a perceived threat that would otherwise eventually cause the breakdown of skin or other localized tissue.

A patient that experiences a tuberculin skin test reaction is experiencing which class of hypersensitivity reactions?

If the patient has an allergy to the tested allergen, then the skin develops a lesion consisting of a flattened reddened area called the wheal and a raised, inflamed area called the flare.

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