Exam 17: Non-Coding Rnas

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Consider the two key roles that have been identified for SRP RNA. You have isolated a mutant SRP RNA. This RNA is able to perform its role as a scaffold for SRP proteins, but has lost its other function. How will this affect translation of SRP-containing proteins?

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Based on what you know about cartilage-hair hypoplasia, which strategy involving ncRNAs do you anticipate would be useful in treating this disease?

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A bacterial ncRNA called OxyS regulates translation by binding to the Shine-Dalgarno sequence, which prevents ribosome binding. What is the function of this ncRNA?

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What ability, which modern eukaryotic cells also possess, did cells in an RNA world probably acquire that explains the existence of DNA?

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piRNA sequences are complimentary to

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An RNA molecule with catalytic activity is called a(n)

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What is the make up of the bacterial and eukaryotic SRP, respectively?

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