Question 1

Which of the following is found at the end of a eukaryotic chromosome?

Accepted Answer

A)  Telomeres 
B)  Centromeres 
C)  Kinetochores 
D)  Origins of replication 
A)  Telomeres 
B)  Centromeres 
C)  Kinetochores 
D)  Origins of replication

Question 2

The different DNA configurations that are generated by super coiling are called topoisomers of one another.

Accepted Answer

A) True 
 B)False

Question 3

The origins of replication in eukaryotic chromosomes are spaced about every ________ base pairs.

Accepted Answer

A)  100,000 
B)  1000 
C)  100 
D)  10 
E)  500 
A)  100,000 
B)  1000 
C)  100 
D)  10 
E)  500

Question 4

A nucleosome is a combination of ________ and ________.

Accepted Answer

A)  histone proteins, scaffold proteins 
B)  RNA, transcription proteins 
C)  DNA, histone proteins 
D)  RNA, histone proteins 
E)  DNA, scaffold proteins 
A)  histone proteins, scaffold proteins 
B)  RNA, transcription proteins 
C)  DNA, histone proteins 
D)  RNA, histone proteins 
E)  DNA, scaffold proteins

Question 5

A Barr body is an example of what?

Accepted Answer

A)  Constitutive heterochromatin 
B)  Facultative heterochromatin 
C)  Constitutive euchromatin 
D)  Facultative euchromatin 
A)  Constitutive heterochromatin 
B)  Facultative heterochromatin 
C)  Constitutive euchromatin 
D)  Facultative euchromatin

Question 6

The 30 nm fiber is formed from arrays of nucleosomes.

Accepted Answer

A) True 
 B)False

Question 7

Where is the bacterial chromosome located?

Accepted Answer

A)  Nucleus 
B)  Nucleolus 
C)  Nucleoid 
D)  Nuclear envelope 
A)  Nucleus 
B)  Nucleolus 
C)  Nucleoid 
D)  Nuclear envelope

Question 8

Areas of the chromosome that remain highly condensed are called ________.

Accepted Answer

A)  Euchromatin 
B)  Facultative heterochromatin 
C)  Constitutive heterochromatin 
D)  Barr body 
A)  Euchromatin 
B)  Facultative heterochromatin 
C)  Constitutive heterochromatin 
D)  Barr body

Question 9

The DNA of a bacterial cell must be compacted about ________ fold to fit within the confines of the cell.

Accepted Answer

A)  10- 
B)  100- 
C)  150- 
D)  1000- 
E)  1,000,000- 
A)  10- 
B)  100- 
C)  150- 
D)  1000- 
E)  1,000,000-

Question 10

The majority of the nonrepetitive genes in an organism are found in which of the following?

Accepted Answer

A)  Unique sequences 
B)  Moderately repetitive sequences 
C)  Highly repetitive sequences 
D)  None of the answers are correct 
A)  Unique sequences 
B)  Moderately repetitive sequences 
C)  Highly repetitive sequences 
D)  None of the answers are correct

Question 11

Where do kinetochores attach to chromosomes?

Accepted Answer

A)  Telomeres 
B)  Specific genes on the chromosome 
C)  Centromeres 
D)  They don't attach to DNA 
A)  Telomeres 
B)  Specific genes on the chromosome 
C)  Centromeres 
D)  They don't attach to DNA

Question 12

DNA topoisomerase I does which of the following?

Accepted Answer

A)  Relax negative supercoils 
B)  Relax positive supercoils 
C)  Introduce negative supercoils 
D)  More than one of the answers are correct 
A)  Relax negative supercoils 
B)  Relax positive supercoils 
C)  Introduce negative supercoils 
D)  More than one of the answers are correct

Question 13

One would expect heterochromatic regions of DNA to be more compacted than euchromatic regions.

Accepted Answer

A) True 
 B)False

Question 14

Digesting chromatin with a high concentration of DNAse I would yield fragments of what approximate size?

Accepted Answer

A)  200 
B)  400 
C)  600 
D)  1100 
A)  200 
B)  400 
C)  600 
D)  1100

Question 15

The zig-zag and solenoid models are associated with the ________ level of DNA organization.

Accepted Answer

A)  histone 
B)  11nm fiber 
C)  beads-on-a-string 
D)  30 nm fiber 
E)  scaffold protein 
A)  histone 
B)  11nm fiber 
C)  beads-on-a-string 
D)  30 nm fiber 
E)  scaffold protein

Question 16

The two processes of wrapping DNA on nucleosomes and arranging them into a 30 nm fiber shorten the DNA by how much?

Accepted Answer

A)  30-fold 
B)  50 fold 
C)  1 million-fold 
D)  3 million-fold 
A)  30-fold 
B)  50 fold 
C)  1 million-fold 
D)  3 million-fold

Question 17

Chemicals such as quinolones are antibacterial. How does it kill bacteria?

Accepted Answer

A)  It inhibits DNA gyrase. 
B)  It inhibits DNA compaction. 
C)  It inhibits DNA replication. 
D)  All of the answers are correct. 
A)  It inhibits DNA gyrase. 
B)  It inhibits DNA compaction. 
C)  It inhibits DNA replication. 
D)  All of the answers are correct.

Question 18

Which of the following is not a mechanism used by bacteria to condense their DNA?

Accepted Answer

A)  Super coiling. 
B)  Packaging the DNA with histone proteins. 
C)  Looping of the DNA. 
D)  Increase or decrease the number of turns in the DNA. 
E)  Anchoring the DNA loops with DNA-binding proteins. 
A)  Super coiling. 
B)  Packaging the DNA with histone proteins. 
C)  Looping of the DNA. 
D)  Increase or decrease the number of turns in the DNA. 
E)  Anchoring the DNA loops with DNA-binding proteins.

Question 19

Why do amphibians have so much more DNA than humans?

Accepted Answer

A)  Amphibians have more repetitive sequences than do humans. 
B)  Amphibians are more biologically complex than mammals. 
C)  Amphibians have more genes than do humans. 
D)  Amphibians are tetraploid, while humans are diploid. 
A)  Amphibians have more repetitive sequences than do humans. 
B)  Amphibians are more biologically complex than mammals. 
C)  Amphibians have more genes than do humans. 
D)  Amphibians are tetraploid, while humans are diploid.

Question 20

The DNA-protein complex in eukaryotic chromosomes is called the genome.

Accepted Answer

A) True 
 B)False

Exam 10: Chromosome Organization and Molecular Structure

Which of the following is found at the end of a eukaryotic chromosome?

The different DNA configurations that are generated by super coiling are called topoisomers of one another.

The origins of replication in eukaryotic chromosomes are spaced about every ________ base pairs.

A nucleosome is a combination of ________ and ________.

A Barr body is an example of what?

The 30 nm fiber is formed from arrays of nucleosomes.

Where is the bacterial chromosome located?

Areas of the chromosome that remain highly condensed are called ________.

The DNA of a bacterial cell must be compacted about ________ fold to fit within the confines of the cell.

The majority of the nonrepetitive genes in an organism are found in which of the following?

Where do kinetochores attach to chromosomes?

DNA topoisomerase I does which of the following?

One would expect heterochromatic regions of DNA to be more compacted than euchromatic regions.

Digesting chromatin with a high concentration of DNAse I would yield fragments of what approximate size?

The zig-zag and solenoid models are associated with the ________ level of DNA organization.

The two processes of wrapping DNA on nucleosomes and arranging them into a 30 nm fiber shorten the DNA by how much?

Chemicals such as quinolones are antibacterial. How does it kill bacteria?

Which of the following is not a mechanism used by bacteria to condense their DNA?

Why do amphibians have so much more DNA than humans?

The DNA-protein complex in eukaryotic chromosomes is called the genome.

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional and Translation Regulation

Gene Regulation in Eukaryotes Ii: Epigenetics

Non-Coding Rnas

Genetics of Viruses

Gene Mutation and Dna Repair

Recombination, Immunogenetics, and Transposition

Molecular Technologies

Biotechnology

Genomics I: Analysis of Dna

Genomics Ii: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Complex and Quantitative Traits

Evolutionary Genetics

Filters

A nucleosome is a combination of and .