Exam 16: Mendelian Inheritance

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You are examining a human pedigree for a trait. You notice that an offspring can be affected even if neither parent is affected. This immediately tells you that the trait is:

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Consider a gene with n alleles A1, A2, ..., An. How many distinct genotypes are possible, taking into account both homozygous and heterozygous genotypes?

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Consider a gene with four alleles A1, A2, A3, and A4. How many distinct homozygous genotypes are possible?

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In genetics, the dash symbol (-) is a "wild card" that stands for either the dominant allele or the recessive allele; for example, A- means the individual has either the genotype AA or Aa. Two genes that undergo independent assortment affect coat color in the house mouse. Each gene has two alleles, one of which is dominant for coat color. Genotypes of the form A- B- have a brownish color called agouti, those of the form A- bb are black, and those of the form aa B- and aa bb are albino (white). What ratio of agouti : black : white is expected from the cross Aa Bb × Aa Bb?

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Imagine that you are standing next to Aristotle in early Greece. You both see an older, balding man with visible age spots on his skin. This man also appears to be a wounded soldier, whose left leg has been amputated. What might Aristotle say to you?

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A true-breeding black rabbit is crossed with a true-breeding white rabbit to produce an F1 generation of 15 individuals. If the black color trait is dominant, which of the following represents the expected phenotype of an F1 generation cross?

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A testcross of an organism of unknown genotype is done when the organism is crossed with an organism that is:

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What is the probability that an individual is Aa or AA if his or her parents are both heterozygous for the trait?

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Consider a gene with six alleles A1, A2, A3, A4, A5, and A6. How many distinct genotypes are possible, taking into account both homozygous and heterozygous genotypes?

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Consider a gene with four alleles A1, A2, A3, and A4. In the cross A1A2 × A3A4, how many offspring genotypes are possible?

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Which of the following represents the expected genotypes of an F2 generation consisting of 8 individuals from an initial cross of a true-breeding black (BB) rabbit and a true-breeding white (bb) rabbit?

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