Exam 12: The Endomembrane System

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead.Which of the following represents the most likely pathway for the protein after it has been completely synthesized?

Comparing cells synthesizing secretory proteins and cells secreting steroid hormones,the cells synthesizing the steroid hormones have

The ________ is the organelle that fuses with endosomes and supplies hydrolytic enzymes necessary for the digestion of the materials.

Exocytosis is stimulated by regional increases in cytoplasmic ________ concentration.

In a lysosomal storage disease,newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes.What is one possible mechanism for this result?

Each of the following is part of the core oligosaccharide side chain in the ER except

Which of the following statements is false regarding phagocytosis?

Using genetic engineering techniques,which of the following would you do to a protein that normally is constitutively secreted to make it accumulate in the ER?

A COPII-coated vesicle has all of the following except

Design an experiment that will allow you to follow a protein from its synthesis to constitutive secretion from the cell.Where would you expect to find the protein at different times during the process? How would the pathway differ if the protein obtained a mannose-6-phosphate modification during transit?

________ is the organelle associated with the functions of steroid biosynthesis,carbohydrate metabolism,and drug detoxification.

Each of the following is an endoplasmic reticulum function except

The plant cell organelle most analogous to animal cell lysosomes is the

In animal cells,oxidation of very long fatty acids occurs in

Each of the following organelles is part of the endomembrane system except

Peroxisomes and the smooth endoplasmic reticulum are both associated with detoxification of harmful substances.How do these two organelles differ with regard to this process?

On which of the following intracellular locations does clathrin organize a coat and form vesicles?

V- and t-________ mediate final docking between vesicle and target membranes.

Each of the following is a lysosomal storage disease caused by a deficiency in lysosomal enzymes except

Pancreatic acinar cells produce and store hydrolytic enzymes in zymogen granules until hormones signal the cell to release the enzymes in a process known as