Exam 12: Adaptive Immunity

Consider a genetic mutation which causes T helper cells to be unable to respond to stimulation by the cytokines which lead to TH₂ differentiation. This mutation would cause a patient to be deficient in which activity?

Which statement is not true about MHC II?

The two- signal activation process for T cells includes

Both the light and the heavy chains of an antibody are involved with epitope recognition and binding.

Which number on the diagram is labeling the portion of the antibody that makes it specific for the antigen is binds to?

How is the immune system able to recognize a limitless number of different antigens and epitopes?

Which lymphocyte type is shown attacking the infected cell in the figure?

The human immunodeficiency virus (HIV) selectively infects any cell which carries the CD4 surface glycoprotein. Which immune function will be impaired?

Cytotoxic T cells eliminate pathogens by

IgE antibody, which is associated with allergic responses,

The difference between T cell activation by normal antigens and T cell activation by superantigens is that superantigens

Advantages of isotype switching include

T cell subclass differentiation allows T cell clones to recognize different epitopes of the same antigen.

By which means of acquiring immunity is likely to produce the longest lasting protection?

All the following apply to T cells except

In contrast to a primary immune response, immunological memory

Graft- versus- host disease occurs when transplanted bone marrow gives rise to B and T cells that attack the recipient's tissues.

An antigen may consist of multiple epitopes, each of which recognized by different lymphocytes.

The humoral immune response can enhance phagocytosis by either direct interaction of antibodies with their antigen, or though antibody activation of the complement cascade.

A patient antibody titer which shows an increasing level of IgM but very little IgG would likely indicate that