Exam 10: Genetic Linkage, Sex-Linkage, and Other Non-Mendelian Inheritance Mechanisms

Match each of the following genetic conditions with its mode of inheritance. A mode of inheritance may be used once, more than once, or not at all. -sickle cell anemia

Figure 10-5 -Which genetic condition is revealed in the karyotype display in Figure 10-5?

Which autosomal dominant genetic trait associated with a gene on human chromosome 4 leads to a type of dwarfing due to defective cartilage formation?

Which of the following best describes sex-linked genes?

Which phrase best defines what is meant by gene linkage?

If two genes are located on different chromosomes, what percentage of the offspring should have a recombinant phenotype?

Which of the following traits determines recombination frequency between two linked genes?

Figure 10-4 -In Figure 10-4, what type of change in the chromosomes is depicted?

Which term refers to an individual with extra or missing copies of some of their chromosomes?

How is the distinctive fur pattern of a calico cat produced?

In Drosophila melanogaster the allele for long wings is dominant over the allele for vestigial wings, and the allele for a grey body is dominant over the allele for a black body. A testcross was done to check for genetic linkage between the genes for these traits, with the following results for the offspring: 410 flies with long wings and a black body 105 flies with long wings and a grey body 390 flies with vestigial wings and a grey body 95 flies with vestigial wings and a black body Which of the following best represents the map distance between the genes for these two traits?

Which term refers to an expression of only one allele of a gene and the silencing of the other allele, all based on which parent contributed each allele?

If two genes on the same chromosome are located 10 map units from each other, what percentage of the offspring should have a recombinant phenotype?

Which sex chromosome combinations would you expect to find in a male calico cat?

About half of all flowering plant species, including many important crop plants, belong to which category of chromosomes?

Suppose two genes a and b are 7.4 map units from each other, and that genes b and c are 5.7 map units from each other. You do a cross to determine the map distance between a and c. Which result would indicate that c lies between a and b?

Which genes are subject to cytoplasmic inheritance?

Which of the following is the molecular mechanism responsible for genomic imprinting?

Match each of the following genetic conditions with its mode of inheritance. A mode of inheritance may be used once, more than once, or not at all. -achondroplasia

Suppose that you are a genetic counsellor, and a man and woman come to you with concerns that if they have a child together, it could have sickle cell anemia. Also suppose that genetic tests reveal that the man and woman are both carriers for sickle cell anemia. Which of the following is the best advice you could give them?