Exam 7: Metabolic Regulation

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Explain the phenomenon known as diauxic growth.Hypothesize why this type of regulation might be important for survival of a microbe in a community as well as a situation where lacking it might be advantageous.

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Quorum sensing requires a strong gradient to be reached before the signaling molecules are transported into the cytoplasm.

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Which of the following IS a characteristic of an isoenzyme?

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Attenuation is a type of regulation that can control

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The biodegradation pathway for benzoate is likely to be subject to induction rather than repression.

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Which regulatory mechanism does NOT depend on a conformational change in protein/enzyme structure to change activity?

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Once the regulatory proteins and effector molecules are made,the actual mechanisms for regulation rarely require net energy input.

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During the biotransformation of a large molecular weight compound,two major products are formed.While one of the products is catabolized,the other compounds accumulation represses the biotransformation of the large compound.Which approach is MOST likely to artificially enhance the biotransformation beyond this point in a batch culture?

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Which type of regulator(s)specifically bind to operator regions of DNA?

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In Bacteria,sensor kinases that respond to extracellular signals transfer this signal to the cytoplasmic machinery by typically phosphorylating the ________ residues.

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In considering the function of heat shock proteins,why is it not a surprise that these proteins are both highly conserved and very ancient? Provide your reasoning.

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When a Bacillus anthracis population suddenly must form spores to survive a harsh nutrient poor environment,how do the cells obtain energy?

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Transcriptional regulation is considered negative when an inducer binds to and deactivates a repressor.

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What are the primary regulator units that control endospore formation?

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Based on their abundance and location in bacterial genomes,deduce which is LEAST likely to horizontally transfer into another bacterium while maintaining its identical function and regulatory roles.

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A common structure for proteins that bind DNA is helix-turn-helix.

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Phosphorylation of ________ regulates which direction a flagellum rotates,thus controlling whether an organism runs or tumbles.

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Depending on the type of regulatory mechanism,activators and repressors can bind to operator regions which control transcription.

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The preferential use of glucose over other available carbon substrates for growth is mechanistically explained by catabolite repression.

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Regulatory proteins

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