Question 1

DiGeorge's syndrome is a developmental defect that prevents the maturation of the thymus.What cell type would be reduced by this condition?

Accepted Answer

A) T cells 
B) B cells 
C) macrophages 
D) lymphocytes 
A) T cells 
B) B cells 
C) macrophages 
D) lymphocytes

Question 2

In Hashimotos's disease,autoantibodies are made against ________,a product of the thyroid gland.

Accepted Answer

A) bacteria 
B) hemoglobin 
C) thyroglobulin 
D) viruses 
A) bacteria 
B) hemoglobin 
C) thyroglobulin 
D) viruses

Question 3

The life-threatening condition that may develop during a type I hypersensitivity reaction is called

Accepted Answer

A) anaphylaxis. 
B) septic shock. 
C) stroke. 
D) toxic shock. 
A) anaphylaxis. 
B) septic shock. 
C) stroke. 
D) toxic shock.

Question 4

People with aggamaglobulinemia do not make protective antibodies and suffer from recurrent,life threatening viral infections,but can develop normal immune responses to bacteria.

Accepted Answer

A) True 
 B)False

Question 5

What is the drawback of live attenuated vaccines?

Accepted Answer

A) They require more secondary reimmunizations than other vaccines. 
B) They are not effective in adults. 
C) They do NOT provide a long-lasting secondary immune response. 
D) They can cause disease in some immunocompromised individuals. 
A) They require more secondary reimmunizations than other vaccines. 
B) They are not effective in adults. 
C) They do NOT provide a long-lasting secondary immune response. 
D) They can cause disease in some immunocompromised individuals.

Question 6

Stem cells are produced and developed in the

Accepted Answer

A) bone marrow. 
B) brain. 
C) liver. 
D) stems of plants. 
A) bone marrow. 
B) brain. 
C) liver. 
D) stems of plants.

Question 7

Dendritic cells are phagocytes with antigen-presenting properties.

Accepted Answer

A) True 
 B)False

Question 8

A diagnostic test for M.tuberculosis exposure

Accepted Answer

A) utilizes an inflammatory reaction that occurs if there has been previous exposure to M.tuberculosis antigens. 
B) relies on previous tuberculin vaccination. 
C) uses an antiserum to detect antibodies in the blood that are only formed if there has been previous exposure to M.tuberculosis antigens. 
D) relies on an innate immune response that occurs only if there has been previous exposure to M.tuberculosis antigens. 
A) utilizes an inflammatory reaction that occurs if there has been previous exposure to M.tuberculosis antigens. 
B) relies on previous tuberculin vaccination. 
C) uses an antiserum to detect antibodies in the blood that are only formed if there has been previous exposure to M.tuberculosis antigens. 
D) relies on an innate immune response that occurs only if there has been previous exposure to M.tuberculosis antigens.

Question 9

Phagocytes interact speedily and effectively with pathogens because they have evolved specialized molecules called pattern recognition receptors (PRRs)that interact directly with PAMPs.

Accepted Answer

A) True 
 B)False

Question 10

Why do individuals with genetic defects that prevent neutrophil or macrophage development usually die at an early age? Be specific and detailed in your answer to demonstrate your knowledge on the role of these cells in the immune system.

Accepted Answer

Individuals with such defects cannot liv

Question 11

The essential protective role for T cell immunity is protection from

Accepted Answer

A) viruses. 
B) extracellular pathogens. 
C) bacteria. 
D) intracellular pathogens. 
A) viruses. 
B) extracellular pathogens. 
C) bacteria. 
D) intracellular pathogens.

Question 12

What is tolerance,and why must the adaptive immune system exhibit tolerance?

Accepted Answer

Tolerance is the acquired inability to m

Question 13

Blood serum contains cells and clotting proteins.

Accepted Answer

A) True 
 B)False

Question 14

T cells interact with the peptide-MHC complex using

Accepted Answer

A) cytokines. 
B) granzyme and perforin. 
C) T-cell receptors. 
D) the antibodies present on the surface of the cell. 
A) cytokines. 
B) granzyme and perforin. 
C) T-cell receptors. 
D) the antibodies present on the surface of the cell.

Question 15

Type I hypersensitivity is caused by the release of vasoactive products from mast cells coated with

Accepted Answer

A) IgA. 
B) IgE. 
C) IgG. 
D) IgM. 
A) IgA. 
B) IgE. 
C) IgG. 
D) IgM.

Question 16

Erythrocytes are the most numerous cells in human blood.

Accepted Answer

A) True 
 B)False

Question 17

An antigen must be at least ________ amino acids long to be effective in a vaccine.

Accepted Answer

A) 10 
B) 25 
C) 50 
D) 100 
A) 10 
B) 25 
C) 50 
D) 100

Question 18

The transfer of antibodies through the placenta from mother to fetus is an example of

Accepted Answer

A) natural passive immunity. 
B) innate immunity. 
C) natural active immunity. 
D) artificial active immunity. 
A) natural passive immunity. 
B) innate immunity. 
C) natural active immunity. 
D) artificial active immunity.

Question 19

Which of the following cell types has NO nucleus?

Accepted Answer

A) erythrocytes 
B) lymphocytes 
C) phagocyte 
D) All of these cells lack a nucleus. 
A) erythrocytes 
B) lymphocytes 
C) phagocyte 
D) All of these cells lack a nucleus.

Question 20

Which of the treatments listed below would be MOST effective for a patient with a genetic defect that causes severe combined immunodeficiency (SCID)?

Accepted Answer

A) intravenous antibiotics 
B) bone marrow transplant 
C) multiple immunizations 
D) repeated doses of antisera 
A) intravenous antibiotics 
B) bone marrow transplant 
C) multiple immunizations 
D) repeated doses of antisera

Exam 24: Immunity and Host Defense

DiGeorge's syndrome is a developmental defect that prevents the maturation of the thymus.What cell type would be reduced by this condition?

In Hashimotos's disease,autoantibodies are made against ________,a product of the thyroid gland.

The life-threatening condition that may develop during a type I hypersensitivity reaction is called

People with aggamaglobulinemia do not make protective antibodies and suffer from recurrent,life threatening viral infections,but can develop normal immune responses to bacteria.

What is the drawback of live attenuated vaccines?

Stem cells are produced and developed in the

Dendritic cells are phagocytes with antigen-presenting properties.

A diagnostic test for M.tuberculosis exposure

Phagocytes interact speedily and effectively with pathogens because they have evolved specialized molecules called pattern recognition receptors (PRRs)that interact directly with PAMPs.

Why do individuals with genetic defects that prevent neutrophil or macrophage development usually die at an early age? Be specific and detailed in your answer to demonstrate your knowledge on the role of these cells in the immune system.

The essential protective role for T cell immunity is protection from

What is tolerance,and why must the adaptive immune system exhibit tolerance?

Blood serum contains cells and clotting proteins.

T cells interact with the peptide-MHC complex using

Type I hypersensitivity is caused by the release of vasoactive products from mast cells coated with

Erythrocytes are the most numerous cells in human blood.

An antigen must be at least ________ amino acids long to be effective in a vaccine.

The transfer of antibodies through the placenta from mother to fetus is an example of

Which of the following cell types has NO nucleus?

Which of the treatments listed below would be MOST effective for a patient with a genetic defect that causes severe combined immunodeficiency (SCID)?

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