Question 1

A recombinant-vector virus would still be effective if the vaccinia virus is unable to express the cloned gene as an antigenic protein.

Accepted Answer

A) True 
 B)False

Question 2

All gram-negative bacteria have lipopolysaccharides in their outer membranes.

Accepted Answer

A) True 
 B)False

Question 3

TH2 cells interact directly with the pathogens.

Accepted Answer

A) True 
 B)False

Question 4

The body's non-inducible,preexisting ability to recognize and destroy pathogens or their products is called

Accepted Answer

A) adaptive immunity. 
B) innate immunity. 
C) phagocytosis. 
D) cytotoxic response. 
A) adaptive immunity. 
B) innate immunity. 
C) phagocytosis. 
D) cytotoxic response.

Question 5

Individuals with severe combined immunodeficiency syndrome (SCID)have a genetic defect that prevents proper formation and expression of immunoglobins and T cells and therefore do not have adaptive immunity.

Accepted Answer

A) True 
 B)False

Question 6

In adaptive immunity,pathogen specific receptors are produced in large numbers only after exposure to the pathogen or its products.

Accepted Answer

A) True 
 B)False

Question 7

Immunity results from the actions of cells that circulate throughout the body,primarily through the blood and lymph.

Accepted Answer

A) True 
 B)False

Question 8

Symptoms of delayed-type hypersensitivity may appear several hours to days after secondary exposure to the eliciting antigen.

Accepted Answer

A) True 
 B)False

Question 9

The inflammatory cytokines IL-1,IL-6,and TNF-α are also

Accepted Answer

A) opsonizing agents that coat foreign cells. 
B) activating cytokines that stimulate Th1 cells to replicate. 
C) capable of producing systemic fever by stimulating the release of prostaglandins in the brain. 
D) part of the complement system that results in the destruction of foreign cells. 
A) opsonizing agents that coat foreign cells. 
B) activating cytokines that stimulate Th1 cells to replicate. 
C) capable of producing systemic fever by stimulating the release of prostaglandins in the brain. 
D) part of the complement system that results in the destruction of foreign cells.

Question 10

Systemic lupus erythematosus (SLE)is an example of a disease caused by type ________ hypersensitivity.

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
A) I 
B) II 
C) III 
D) IV

Question 11

Superantigens produce a harmful immune response because

Accepted Answer

A) they activate too many T cells,causing excessive inflammation and cell damage. 
B) they initiate a type I allergic response resulting in excessive inflammation. 
C) too many phagocytes are activated and destroy host tissue. 
D) a strong immune response is necessary to protect the host from the pathogen. 
A) they activate too many T cells,causing excessive inflammation and cell damage. 
B) they initiate a type I allergic response resulting in excessive inflammation. 
C) too many phagocytes are activated and destroy host tissue. 
D) a strong immune response is necessary to protect the host from the pathogen.

Question 12

Which of the following immunogens is MOST effective as a vaccine?

Accepted Answer

A) chemically inactivated bacteria 
B) dead virus 
C) live virus 
D) toxoid 
A) chemically inactivated bacteria 
B) dead virus 
C) live virus 
D) toxoid

Question 13

Blood and lymph have the following in common EXCEPT

Accepted Answer

A) nucleated cells. 
B) proteins. 
C) red blood cells. 
D) none of these 
A) nucleated cells. 
B) proteins. 
C) red blood cells. 
D) none of these

Question 14

What are the primary chemical mediators released from mast cells during a type I hypersensitivity reaction?

Accepted Answer

A) antibodies 
B) interleukin I and tumor necrosis factor 
C) histamine and serotonin 
D) cytokines 
A) antibodies 
B) interleukin I and tumor necrosis factor 
C) histamine and serotonin 
D) cytokines

Question 15

The rapid increase in adaptive immunity after a second antigen exposure is called

Accepted Answer

A) immune memory. 
B) specificity. 
C) tolerance. 
D) immune memory,specificity,or tolerance. 
A) immune memory. 
B) specificity. 
C) tolerance. 
D) immune memory,specificity,or tolerance.

Question 16

The purposeful artificial stimulation of active immunity to a particular infectious disease is known as

Accepted Answer

A) immunodeficiency. 
B) hypersensitivity. 
C) immunization. 
D) opsonization. 
A) immunodeficiency. 
B) hypersensitivity. 
C) immunization. 
D) opsonization.

Question 17

The secondary lymphoid organs consist of the following EXCEPT

Accepted Answer

A) lymph nodes. 
B) mucosal-associated lymphoid tissue (MALT). 
C) spleen. 
D) All of these organs are secondary lymphoid organs. 
A) lymph nodes. 
B) mucosal-associated lymphoid tissue (MALT). 
C) spleen. 
D) All of these organs are secondary lymphoid organs.

Question 18

Monocytes and granulocytes are the two lineages of myeloid cells.

Accepted Answer

A) True 
 B)False

Question 19

Vaccines can be developed from synthetic peptides.

Accepted Answer

A) True 
 B)False

Question 20

Why are secondary or "booster" reimmunizations given?

Accepted Answer

A) Secondary immunizations are necessary for an innate immune response. 
B) Secondary reimmunizations produce a secondary immune response and boost antibody titers. 
C) Secondary reimmunizations produce a phagocytic immune response that is longer lasting than the primary immune response. 
D) Frequent secondary reimmunizations are needed because the immune system doesn't remember antigens for more than a few years. 
A) Secondary immunizations are necessary for an innate immune response. 
B) Secondary reimmunizations produce a secondary immune response and boost antibody titers. 
C) Secondary reimmunizations produce a phagocytic immune response that is longer lasting than the primary immune response. 
D) Frequent secondary reimmunizations are needed because the immune system doesn't remember antigens for more than a few years.

Exam 24: Immunity and Host Defense

A recombinant-vector virus would still be effective if the vaccinia virus is unable to express the cloned gene as an antigenic protein.

All gram-negative bacteria have lipopolysaccharides in their outer membranes.

TH2 cells interact directly with the pathogens.

The body's non-inducible,preexisting ability to recognize and destroy pathogens or their products is called

Individuals with severe combined immunodeficiency syndrome (SCID)have a genetic defect that prevents proper formation and expression of immunoglobins and T cells and therefore do not have adaptive immunity.

In adaptive immunity,pathogen specific receptors are produced in large numbers only after exposure to the pathogen or its products.

Immunity results from the actions of cells that circulate throughout the body,primarily through the blood and lymph.

Symptoms of delayed-type hypersensitivity may appear several hours to days after secondary exposure to the eliciting antigen.

The inflammatory cytokines IL-1,IL-6,and TNF-α are also

Systemic lupus erythematosus (SLE)is an example of a disease caused by type ________ hypersensitivity.

Superantigens produce a harmful immune response because

Which of the following immunogens is MOST effective as a vaccine?

Blood and lymph have the following in common EXCEPT

What are the primary chemical mediators released from mast cells during a type I hypersensitivity reaction?

The rapid increase in adaptive immunity after a second antigen exposure is called

The purposeful artificial stimulation of active immunity to a particular infectious disease is known as

The secondary lymphoid organs consist of the following EXCEPT

Monocytes and granulocytes are the two lineages of myeloid cells.

Vaccines can be developed from synthetic peptides.

Why are secondary or "booster" reimmunizations given?

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