Question 1

The peptides bound by a single MHC protein share a common

Accepted Answer

A) C domain. 
B) peptide motif. 
C) V domain. 
D) nucleotide sequence. 
A) C domain. 
B) peptide motif. 
C) V domain. 
D) nucleotide sequence.

Question 2

After a B cell is activated,it no longer needs T cell interactions or cytokines to make antibody.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following is/are MHC class I genes?

Accepted Answer

A) HLA-A 
B) HLA-B 
C) HLA-C 
D) HLA-A,HLA-B,and HLA-C 
A) HLA-A 
B) HLA-B 
C) HLA-C 
D) HLA-A,HLA-B,and HLA-C

Question 4

The PAMP recognized by mannose-binding lectin (MBL)is the sugar mannose,found as a repeating subunit in

Accepted Answer

A) human mucus. 
B) lymphocyte receptors. 
C) bacterial and fungal polysaccharides. 
D) bacterial peptidoglycan. 
A) human mucus. 
B) lymphocyte receptors. 
C) bacterial and fungal polysaccharides. 
D) bacterial peptidoglycan.

Question 5

The complete second signal for B cell activation requires which of the following interactions?

Accepted Answer

A) CD40-CK40L interaction 
B) cytokine-cytokine receptor interaction 
C) TH-B cell interaction 
D) All of these are necessary. 
A) CD40-CK40L interaction 
B) cytokine-cytokine receptor interaction 
C) TH-B cell interaction 
D) All of these are necessary.

Question 6

Amino acid variability is especially apparent in several ________ in the V domains of different immunoglobulins.

Accepted Answer

A) heavy chains 
B) complementarity-determining regions (CDR) 
C) peptide motifs 
D) epitopes 
A) heavy chains 
B) complementarity-determining regions (CDR) 
C) peptide motifs 
D) epitopes

Question 7

Immunoglobulins and TCRs associate with adaptor molecules that have

Accepted Answer

A) a C domain. 
B) immune-based tyrosine-activation motifs (ITAMs). 
C) pathogen recognition receptors. 
D) toll-like receptors. 
A) a C domain. 
B) immune-based tyrosine-activation motifs (ITAMs). 
C) pathogen recognition receptors. 
D) toll-like receptors.

Question 8

Some activated B cells are transformed into ________ cells that secrete antibodies,and others remain as ________ cells.

Accepted Answer

A) plasma / memory B 
B) lymphocytes / memory B 
C) immunoglobulin / plasma 
D) immunoglobulin / TH 
A) plasma / memory B 
B) lymphocytes / memory B 
C) immunoglobulin / plasma 
D) immunoglobulin / TH

Question 9

Adapter molecules associate covalently with their respective antigen receptors in the membrane.

Accepted Answer

A) True 
 B)False

Question 10

The ________ is a highly conserved amino acid sequence found in immunoglobulin,TCR,and MHC proteins.

Accepted Answer

A) heavy chain 
B) V domain 
C) C domain 
D) light chain 
A) heavy chain 
B) V domain 
C) C domain 
D) light chain

Question 11

The clonal selection theory states that each antigen-reactive B cell or T cell has a cell surface receptor for a single antigen epitope.

Accepted Answer

A) True 
 B)False

Question 12

Antibodies consist of four polypeptides,________ heavy chains,and ________ light chains.

Accepted Answer

A) one / three 
B) two / two 
C) three / one 
D) four / four 
A) one / three 
B) two / two 
C) three / one 
D) four / four

Question 13

Major histocompatibility complex (MHC)proteins,antibodies,and T cell receptors are all highly variable so that they can interact with a large number of different antigens.How is variability generated for each of these important antigen-binding proteins?

Accepted Answer

MHC proteins are polygenic.Three differe

Question 14

The C domain of antigen-binding proteins functions to

Accepted Answer

A) attach the antigen-binding domain to the cytoplasmic membrane. 
B) bind to the cytoplasmic membrane of foreign cells. 
C) complex multiple antigen-binding proteins together. 
D) bind to epitopes. 
A) attach the antigen-binding domain to the cytoplasmic membrane. 
B) bind to the cytoplasmic membrane of foreign cells. 
C) complex multiple antigen-binding proteins together. 
D) bind to epitopes.

Question 15

More than ________ % of all T cell precursors that enter the thymus do NOT survive the selection process.

Accepted Answer

A) 15 
B) 25 
C) 45 
D) 95 
A) 15 
B) 25 
C) 45 
D) 95

Question 16

In clonal selection,cells that have not interacted with antigen do not proliferate.

Accepted Answer

A) True 
 B)False

Question 17

The major histocompatibility complex is also called the

Accepted Answer

A) human leukocyte antigen (HL
A) . 
B) T cell receptor. 
C) toll-like receptor complex. 
D) T cell receptor or toll-like receptor. 
A) human leukocyte antigen (HL
A) . 
B) T cell receptor. 
C) toll-like receptor complex. 
D) T cell receptor or toll-like receptor.

Question 18

An epitope is ________ amino acids long.

Accepted Answer

A) 3-5 
B) 10-15 
C) 50-60 
D) 700 
A) 3-5 
B) 10-15 
C) 50-60 
D) 700

Question 19

The antigen-binding site of an antibody accommodates a small portion of the antigen called a(n)

Accepted Answer

A) lipopolysaccharide. 
B) epitope. 
C) peptide motif. 
D) pathogen associated molecular pattern (PAMP). 
A) lipopolysaccharide. 
B) epitope. 
C) peptide motif. 
D) pathogen associated molecular pattern (PAMP).

Question 20

TCRs are found exclusively on T cells.

Accepted Answer

A) True 
 B)False

Exam 26: Molecular Immunology

The peptides bound by a single MHC protein share a common

After a B cell is activated,it no longer needs T cell interactions or cytokines to make antibody.

Which of the following is/are MHC class I genes?

The PAMP recognized by mannose-binding lectin (MBL)is the sugar mannose,found as a repeating subunit in

The complete second signal for B cell activation requires which of the following interactions?

Amino acid variability is especially apparent in several ________ in the V domains of different immunoglobulins.

Immunoglobulins and TCRs associate with adaptor molecules that have

Some activated B cells are transformed into ________ cells that secrete antibodies,and others remain as ________ cells.

Adapter molecules associate covalently with their respective antigen receptors in the membrane.

The ________ is a highly conserved amino acid sequence found in immunoglobulin,TCR,and MHC proteins.

The clonal selection theory states that each antigen-reactive B cell or T cell has a cell surface receptor for a single antigen epitope.

Antibodies consist of four polypeptides,________ heavy chains,and ________ light chains.

Major histocompatibility complex (MHC)proteins,antibodies,and T cell receptors are all highly variable so that they can interact with a large number of different antigens.How is variability generated for each of these important antigen-binding proteins?

The C domain of antigen-binding proteins functions to

More than ________ % of all T cell precursors that enter the thymus do NOT survive the selection process.

In clonal selection,cells that have not interacted with antigen do not proliferate.

The major histocompatibility complex is also called the

An epitope is ________ amino acids long.

The antigen-binding site of an antibody accommodates a small portion of the antigen called a(n)

TCRs are found exclusively on T cells.

Microorganisms and Microbiology

Microbial Cell Structure and Function

Microbial Metabolism

Molecular Biology

Microbial Growth and Control

Microbial Genomics

Metabolic Regulation

Viruses and Virology

Viral Genomes and Diversity

Genetics of Bacteria and Archaea

Genetic Engineering and Biotechnology

Microbial Evolution and Systematics

Metabolic Diversity of Microorganisms

Functional Diversity of Bacteria

Diversity of Bacteria

Diversity of Archaea

Diversity of Eukaryotic Microorganisms

Methods in Microbial Ecology

Microbial Ecosystems

Nutrient Cycles

Microbiology of the Built Environment

Microbial Symbioses

Microbial Interactions With Humans

Immunity and Host Defense

Immune Mechanisms

Diagnostic Microbiology

Epidemiology

Person-To-Person Bacterial and Viral Diseases

Vectorborne and Soilborne Bacterial and Viral Diseases

Water and Food As Vehicles of Bacterial Diseases

Eukaryotic Pathogens: Fungal and Parasitic Diseases

Filters

Some activated B cells are transformed into cells that secrete antibodies,and others remain as cells.

Antibodies consist of four polypeptides, heavy chains,and light chains.