Exam 15: Gene Regulation in Eukaryotes I: Transcriptional Regulation

Which of the following is the most likely location of an insulator sequence?

DNA methylation usually activates gene expression.

The exons of a gene are always expressed in a functional protein.

Prior to hormone binding, receptors for steroid hormones are usually found in the nucleus of the cell.

A repressor protein would enhance the ability of TFIID to bind to the TATA box of the promoter.

Activator proteins bind to silencer sequences and repressor proteins bind to enhancer sequences.

Nucleosome location may be changed by a process called ATP-dependent chromatin remodeling.

Histone acetyltransferases are directly involved in which of the following?

In ChIP-Seq, the DNA fragments to be sequenced are around 150 bp in length. What does this size of DNA represent?

Transcription factors are proteins that influence the ability of the RNA polymerase to transcribe a gene.

What basal transcription factor is most often affected by regulatory transcription factors?

Which of the following is a major finding from the ENCODE project?

Insulators exert their effects on gene expression through histone acetyltransferase, histone deacetylase, and RNA polymerase.

CpG islands are associated with which of the following?

What activates CREB?

Steroid hormomes are an example of an effector which regulates regulatory transcription factor activity.

Methylation of DNA bases is one way that regulatory transcription factors may influence gene expression.

Housekeeping genes are unmethylated and active in most cells.

For which of the following histones has variant forms not yet been identified?